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Akademický článek

Temporal Dynamics of Cardiovascular Risk in Patients with Chronic Obstructive Pulmonary Disease During Stable Disease and Exacerbations: Review of the Mechanisms and Implications

Autor: Simons SO, Heptinstall AB, Marjenberg Z, Marshall J, Mullerova H, Rogliani P, Nordon C, Hawkins NM

Publikováno v: International Journal of COPD, Vol Volume 19, Pp 2259-2271 (2024)

Sami O Simons,1,2 Amy B Heptinstall,3 Zoe Marjenberg,3 Jonathan Marshall,4 Hana Mullerova,4 Paola Rogliani,5 Clementine Nordon,4 Nathaniel M Hawkins6 1Department of Respiratory Medicine, NUTRIM Institute for Nutrition and Translational Research in Me

Externí odkaz: https://doaj.org/article/480d1f8cbd7c44a58ecd99d23810e139

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The Effect of Particle Size and Concentration on Low-Frequency Terahertz Scattering in Granular Compacts

Autor: Murphy, Keir N, Naftaly, Mira, Nordon, Alison, Markl, Daniel

Fundamental knowledge of scattering in granular compacts is essential to ensure accuracy of spectroscopic measurements and determine material characteristics such as size and shape of scattering objects. Terahertz time-domain spectroscopy (THz-TDS) w

Externí odkaz: http://arxiv.org/abs/2304.10974

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Akademický článek

Factors associated with non-fatal heart failure and atrial fibrillation or flutter within the first 30 days post COPD exacerbation: a nested case-control study

Autor: Emily L. Graul, Clementine Nordon, Kirsty Rhodes, Shruti Menon, Mahmoud Al Ammouri, Constantinos Kallis, Anne E. Ioannides, Hannah R. Whittaker, Nicholas S. Peters, Jennifer K. Quint

Publikováno v: BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-12 (2024)

Abstract Background An immediate, temporal risk of heart failure and arrhythmias after a Chronic Obstructive Pulmonary Disease (COPD) exacerbation has been demonstrated, particularly in the first month post-exacerbation. However, the clinical profile

Externí odkaz: https://doaj.org/article/5d521aa9554c49409c83e9d38dbcea4c

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Akademický článek

Elucidating the risk of cardiopulmonary consequences of an exacerbation of COPD: results of the EXACOS-CV study in Germany

Autor: Hana Müllerova, Clementine Nordon, Patrick Timpel, Kirsty Rhodes, Claus F Vogelmeier, Edeltraut Garbe, Melanie Abram, Marija Halbach, Nils Kossack, Nikolaus Kolb

Publikováno v: BMJ Open Respiratory Research, Vol 11, Iss 1 (2024)

Background Exacerbations of chronic obstructive pulmonary disease (COPD) represent a period of vulnerability. This study explored the association between time periods following an exacerbation and the risk of severe cardiovascular (CV) events or deat

Externí odkaz: https://doaj.org/article/2058ed21aab94def965644460836c9c2

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Akademický článek

Risk of Death and Cardiovascular Events Following an Exacerbation of COPD: The EXACOS-CV US Study

Autor: Daniels K, Lanes S, Tave A, Pollack MF, Mannino DM, Criner G, Neikirk A, Rhodes K, Feigler N, Nordon C

Publikováno v: International Journal of COPD, Vol Volume 19, Pp 225-241 (2024)

Kimberly Daniels,1 Stephan Lanes,1 Arlene Tave,1 Michael F Pollack,2 David M Mannino,3 Gerard Criner,4 Amanda Neikirk,1 Kirsty Rhodes,5 Norbert Feigler,2 Clementine Nordon5 1Safety and Epidemiology, Carelon Research, Wilmington, DE, USA; 2Global Medi

Externí odkaz: https://doaj.org/article/19e2cbf1da454448be72b82fda83ae57

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Akademický článek

Risk of cardiovascular events after an exacerbation of chronic obstructive pulmonary disease: results from the EXACOS-CV cohort study using the PHARMO Data Network in the Netherlands

Autor: Karin M. A. Swart, Brenda N. Baak, Louise Lemmens, Fernie J. A. Penning-van Beest, Camilla Bengtsson, Muriel Lobier, Fabian Hoti, Dina Vojinovic, Lindy van Burk, Kirsty Rhodes, Edeltraut Garbe, Ron M. C. Herings, Clementine Nordon, Sami O. Simons

Publikováno v: Respiratory Research, Vol 24, Iss 1, Pp 1-10 (2023)

Abstract Background People living with chronic obstructive pulmonary disease (COPD) have an increased risk of experiencing cardiovascular (CV) events, particularly after an exacerbation. Such CV burden is not yet known for incident COPD patients. We

Externí odkaz: https://doaj.org/article/b7f1bda75ac343adbd4dcaa1bfb633cd

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Akademický článek

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Akademický článek

History of Respiratory Events Prior to a First COPD Diagnosis and Future Exacerbations: A Longitudinal Observational Cohort Database Study in Japan

Autor: Ding B, Zaha R, Makita N, Graham S, Lambrelli D, Huse S, Müllerová H, Nordon C, Muro S

Publikováno v: International Journal of COPD, Vol Volume 18, Pp 247-258 (2023)

Bo Ding,1 Rebecca Zaha,2 Naoyuki Makita,3 Sophie Graham,4,5 Dimitra Lambrelli,4 Samuel Huse,6 Hana Müllerová,7 Clementine Nordon,7 Shigeo Muro8 1BioPharmaceuticals Medical, AstraZeneca, Gothenburg, Sweden; 2Formerly of Data Analytics, Evidera, Beth

Externí odkaz: https://doaj.org/article/d8fbf75998604e11afc704a6ad8d9d77

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Akademický článek

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Akademický článek

Testing the 'RCT augmentation' methodology: A trial simulation study to guide the broadening of trials eligibility criteria and inform on effectiveness

Autor: Clementine Nordon, Benoit Sanchez, Mei Zhang, Xiaowei Wang, Phillip Hunt, Mark Belger, Helene Karcher

Publikováno v: Contemporary Clinical Trials Communications, Vol 33, Iss , Pp 101142- (2023)

Background: Exclusion criteria that are treatment effect modifiers (TEM) decrease RCTs results generalisability and the potentials of effectiveness estimation. In “augmented RCTs”, a small proportion of otherwise-excluded patients are included to

Externí odkaz: https://doaj.org/article/cc82de7d21324183b203cdb3c23368dd

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