Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Norberto Ariel Gandini"'
Autor:
Julian Naipauer, Martín Carlos Abba, Edith C. Kordon, Norberto Ariel Gandini, Maria Marta Facchinetti, Romina Canzoneri, A. Rodriguez Peña, Micaela Nadia Stedile, Ezequiel Lacunza, Alejandro Carlos Curino, Omar A. Coso
Publikováno v:
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
Universidad Nacional de La Plata
instacron:UNLP
It has been established that ZFP36 (also known as Tristetraprolin or TTP) promotes mRNA degradation of proteins involved in inflammation, proliferation and tumor invasiveness. In mammary epithelial cells ZFP36 expression is induced by STAT5 activatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc013df10613f3f2f0f3135b235db8c5
https://pubmed.ncbi.nlm.nih.gov/32248342/
https://pubmed.ncbi.nlm.nih.gov/32248342/
Autor:
Georgina Pamela Coló, Marilina Mascaró, Maria Marta Facchinetti, Martín Carlos Abba, Norberto Ariel Gandini, María Eugenia Fermento, María Julia Ferronato, Eliana Noelia Alonso, Julián Arévalo, Myriam Nuñez, Pamela Pichel, Alejandro Carlos Curino, Josefina Alejandra Guevara
Publikováno v:
Antioxidants & Redox Signaling. 30
Aims:Heme oxygenase-1 (HO-1) is an enzyme involved in cellular responses to oxidative stress and has alsobeen shown to regulate processes related to cancer progression. In this regard, HO-1 has been shown to displaya dual effect with either antitumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d79e1ed0f653b56423852754b5f6278
https://doi.org/10.1089/ars.2018.7554
https://doi.org/10.1089/ars.2018.7554
Autor:
María Belén Novoa Díaz, Claudia Gentili, Exequiel Alonso, María José Torres, Natalia Calvo, Héctor R. Contreras, Alexander Herrera, Fernanda López-Moncada, Pedro Carriere, Norberto Ariel Gandini, Graciela Gigola
Publikováno v:
Molecular and Cellular Endocrinology. 530:111253
Parathyroid hormone-related peptide (PTHrP) exerts its effects on cells derived from colorectal cancer (CRC) and tumor microenvironment and is involved in processes requiring the epithelial-mesenchymal transition (EMT). Here, we report that PTHrP mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::958c6ec95bb49c00f78ebe63585dae98
https://doi.org/10.1016/j.mce.2021.111253
https://doi.org/10.1016/j.mce.2021.111253
Antitumoral and antimetastatic activity of Maitake D-Fraction in triple-negative breast cancer cells
Autor:
María Julia Ferronato, Alejandro López Romero, Josefina Alejandra Guevara, Norberto Ariel Gandini, Maria Marta Facchinetti, María Eugenia Fermento, Alejandro Carlos Curino, Eliana Noelia Alonso
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Oncotarget
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Oncotarget
Triple-negative breast cancer (TNBC) is associated with poor prognosis, high local recurrence rate and high rate of metastasis compared with other breast cancer subtypes. In addition, TNBC lacks a targeted therapy. This scenario highlights the need f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdece524e05e26008b0e310f5470e6ad
http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path[]=25174&path[]=78890
http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path[]=25174&path[]=78890
Autor:
Alejandro Carlos Curino, Norberto Ariel Gandini, Maria Marta Facchinetti, Yagamare Fall, Marcos L. Rivadulla, Generosa Gómez, Alejandro López Romero, María Eugenia Fermento, María Julia Ferronato, Débora Gisele Salomón, Manuel Pérez, Xenxo Pérez-García
Publikováno v:
Archiv der Pharmazie. 348:315-329
The active form of vitamin D3, 1α,25(OH)2D3, plays a major role in maintaining calcium/phosphate homeostasis. In addition, it is a potent antiproliferative and pro-differentiating agent. Unfortunately, it usually causes hypercalcemia in vivo when ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4870222a27f2e501ec038bf7df0be06
https://doi.org/10.1002/ardp.201400448
https://doi.org/10.1002/ardp.201400448
Autor:
Evangelina Mascaró, Alejandro Carlos Curino, Norberto Ariel Gandini, Eliana Noelia Alonso, Cristian Vitale, María Julia Ferronato, Maria Marta Facchinetti, Yagamare Fall, María Eugenia Fermento, Débora Gisele Salomón, Mario Alfredo Quevedo
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 178
Glioblastoma multiforme (GBM) is the worst and most common brain tumor, characterized by high proliferation and invasion rates. The current standard treatment is mainly based on chemoradiotherapy and this approach has slightly improved patient surviv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84f0dab7dbfe3d7475ae9af1d86f93b8
https://pubmed.ncbi.nlm.nih.gov/29102624
https://pubmed.ncbi.nlm.nih.gov/29102624
Autor:
Maria Marta Facchinetti, María Eugenia Fermento, Jean C. Zenklusen, Débora Gisele Salomón, Norberto Ariel Gandini, María Julia Ferronato, Julián Arévalo, Jorge Alejandro Blasco, Alejandro Carlos Curino, Nancy Carolina Andrés
Publikováno v:
Journal of Neuro-Oncology. 118:49-60
Vitamin D and its analogs have been shown to display anti-proliferative effects in a wide variety of cancer types including glioblastoma multiforme (GBM). These anticancer effects are mediated by its active metabolite, 1α, 25-dihydroxyvitamin D3 (ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa2a80ed560894f76b231be9fbf4dd1
https://doi.org/10.1007/s11060-014-1416-3
https://doi.org/10.1007/s11060-014-1416-3
Autor:
Maria Marta Facchinetti, Norberto Ariel Gandini, María Julia Ferronato, Julián Arévalo, Eliana Noelia Alonso, María Emilia Villegas, Alejandro López Romero, Diego Javier Obiol, María Eugenia Fermento, Alejandro Carlos Curino
Publikováno v:
Nutrition and cancer. 69(1)
D-Fraction is protein-bound β-1,6 and β-1,3 glucans (proteoglucan) extracted from the edible and medicinal mushroom Grifola frondosa (Maitake). The antitumoral effect of D-Fraction has long been exclusively attributed to their immunostimulatory cap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c41acaa9dd8a554555ce210fbabbd3
https://pubmed.ncbi.nlm.nih.gov/27892708
https://pubmed.ncbi.nlm.nih.gov/27892708
Autor:
Yagamare Fall, María Eugenia Fermento, Generosa Gómez, Maria Marta Facchinetti, María Emilia Villegas, Alejandro Carlos Curino, Alejandro López Romero, María Julia Ferronato, Marcos L. Rivadulla, Julián Arévalo, Norberto Ariel Gandini, Eliana Noelia Alonso, Mario Alfredo Quevedo
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Vitamin D has been shown to display a wide variety of antitumour effects, but their therapeutic use is limited by its severe side effects. We have designed and synthesized a Gemini vitamin D analogue of calcitriol (UVB1) which has shown to display an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::226ca7f59f49951c57aee54bd9c19731
https://www.sciencedirect.com/science/article/pii/S0960076016301492
https://www.sciencedirect.com/science/article/pii/S0960076016301492
Autor:
Javier Enrique Mendizábal, Maria Marta Facchinetti, Alejandro Carlos Curino, Stephen M. Hewitt, Maria Sol Degese, Omar A. Coso, Alfredo A. Molinolo, Norberto Ariel Gandini, J. Silvio Gutkind
Publikováno v:
Lung Cancer
While changes in heme oxygenase (HO-1) in lung cancer have already been reported, conflicting results were obtained for enzyme expression in human lung cancer specimens. Therefore, the aim of this work was to study HO-1 expression in a large collecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f50c392fb931dff4d1b042c38829e50
https://doi.org/10.1016/j.lungcan.2012.02.016
https://doi.org/10.1016/j.lungcan.2012.02.016