Zobrazeno 1 - 10
of 359
pro vyhledávání: '"Norberto, Ortego Centeno"'
Autor:
Ángel Luís Castaño-Núñez, Marco-Antonio Montes-Cano, José-Raúl García-Lozano, Norberto Ortego-Centeno, Francisco José García-Hernández, Gerard Espinosa, Genaro Graña-Gil, Juan Sánchez-Bursón, María Rosa Juliá, Roser Solans, Ricardo Blanco, Ana-Celia Barnosi-Marín, Ricardo Gómez de la Torre, Patricia Fanlo, Mónica Rodríguez-Carballeira, Luis Rodríguez-Rodríguez, Teresa Camps, Santos Castañeda, Juan-Jose Alegre-Sancho, Javier Martín, María Francisca González-Escribano
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe knowledge of the aetiology of Behçet disease (BD), an immune-mediated vasculitis, is limited. HLA-B, mainly HLA-B51, and HLA-A molecules are associated with disease, but the ultimate cause of this association remains obscure. There i
Externí odkaz:
https://doaj.org/article/79971d0e6149449ab809dbe2149f9a0a
Autor:
Alfredo Guillén-Del-Castillo, Manuel López Meseguer, Vicent Fonollosa-Pla, Berta Sáez Giménez, Dolores Colunga-Argüelles, Eva Revilla-López, Manuel Rubio-Rivas, Maria Jose Cristo Ropero, Ana Argibay, Joan Albert Barberá Mir, Xavier Pla Salas, Amaya Martínez Meñaca, Ana Belén Madroñero Vuelta, Antonio Lara Padrón, Luis Sáez Comet, Juan Antonio Domingo Morera, Cristina González-Echávarri, Teresa Mombiela, Norberto Ortego-Centeno, Manuela Marín González, Carles Tolosa-Vilella, Isabel Blanco, Pilar Escribano Subías, Carmen Pilar Simeón-Aznar, RESCLE Consortium, REHAP Consortium
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract To assess severity markers and outcomes of patients with systemic sclerosis (SSc) with or without pulmonary arterial hypertension (PAH-SSc/non-PAH-SSc), and the impact of interstitial lung disease (ILD) on PAH-SSc. Non-PAH-SSc patients from
Externí odkaz:
https://doaj.org/article/dbfcb5791dff4a5388fa75db31fa8f36
Autor:
Diana Prieto-Peña, Sara Remuzgo-Martínez, Fernanda Genre, Verónica Pulito-Cueto, Belén Atienza-Mateo, Javier Llorca, Belén Sevilla-Pérez, Norberto Ortego-Centeno, Ana Marquez, Leticia Lera-Gómez, María Teresa Leonardo, Ana Peñalba, Javier Narváez, Luis Martín-Penagos, Emilio Rodrigo, José A. Miranda-Filloy, Luis Caminal-Montero, Paz Collado, Javier Sánchez Pérez, Diego de Argila, Esteban Rubio, Manuel León Luque, Juan María Blanco-Madrigal, Eva Galíndez-Agirregoikoa, Oreste Gualillo, Javier Martín, Santos Castañeda, Ricardo Blanco, Miguel A. González-Gay, Raquel López-Mejías
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Cytokines signalling pathway genes are crucial factors of the genetic network underlying the pathogenesis of Immunoglobulin-A vasculitis (IgAV), an inflammatory vascular condition. An influence of the interleukin (IL)33- IL1 receptor like (I
Externí odkaz:
https://doaj.org/article/4e5c12cf144c4687a3cac75fff04094d
Autor:
Diana Prieto-Peña, Fernanda Genre, Sara Remuzgo-Martínez, Verónica Pulito-Cueto, Belén Atienza-Mateo, Javier Llorca, Belén Sevilla-Pérez, Norberto Ortego-Centeno, Leticia Lera-Gómez, María Teresa Leonardo, Ana Peñalba, Javier Narváez, Luis Martín-Penagos, Emilio Rodrigo, José A. Miranda-Filloy, Luis Caminal-Montero, Paz Collado, Javier Sánchez Pérez, Diego de Argila, Esteban Rubio, Manuel León Luque, Juan María Blanco-Madrigal, Eva Galíndez-Agirregoikoa, Oreste Gualillo, Javier Martín, Santos Castañeda, Ricardo Blanco, Miguel A. González-Gay, Raquel López-Mejías
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract BAFF, APRIL and BAFF-R are key proteins involved in the development of B-lymphocytes and autoimmunity. Additionally, BAFF, APRIL and BAFFR polymorphisms were associated with immune-mediated conditions, being BAFF GCTGT>A a shared insertion-d
Externí odkaz:
https://doaj.org/article/cca02dff696e45aaac327228db5c45bf
Autor:
Elena López-Isac, Marialbert Acosta-Herrera, Martin Kerick, Shervin Assassi, Ansuman T. Satpathy, Jeffrey Granja, Maxwell R. Mumbach, Lorenzo Beretta, Carmen P. Simeón, Patricia Carreira, Norberto Ortego-Centeno, Ivan Castellvi, Lara Bossini-Castillo, F. David Carmona, Gisela Orozco, Nicolas Hunzelmann, Jörg H. W. Distler, Andre Franke, Claudio Lunardi, Gianluca Moroncini, Armando Gabrielli, Jeska de Vries-Bouwstra, Cisca Wijmenga, Bobby P. C. Koeleman, Annika Nordin, Leonid Padyukov, Anna-Maria Hoffmann-Vold, Benedicte Lie, European Scleroderma Group, Susanna Proudman, Wendy Stevens, Mandana Nikpour, Australian Scleroderma Interest Group (ASIG), Timothy Vyse, Ariane L. Herrick, Jane Worthington, Christopher P. Denton, Yannick Allanore, Matthew A. Brown, Timothy R. D. J. Radstake, Carmen Fonseca, Howard Y. Chang, Maureen D. Mayes, Javier Martin
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Systemic sclerosis (SSc) is a heterogeneous chronic autoimmune disease that affects the connective tissue. Here, López-Isac et al. identify 13 new risk loci for SSc as well as loci specific for limited cutaneous and diffuse SSc and, defining credibl
Externí odkaz:
https://doaj.org/article/2c83b5b19dd94142a96da7824aa29e78
Publikováno v:
BMC Geriatrics, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Background Giant cell arteritis is a vasculitis of large and middle-sized arteries that affects patients aged over 50 years. It can show a typical clinical picture consisting of cranial manifestations but sometimes nonspecific symptoms and l
Externí odkaz:
https://doaj.org/article/68e0dfeadb1d4770bc4271d5842b7f2e
Autor:
Alfredo Guillén-Del-Castillo, Manuel López Meseguer, Vicent Fonollosa-Pla, Berta Sáez Giménez, Dolores Colunga-Argüelles, Eva Revilla-López, Manuel Rubio-Rivas, Maria Jose Cristo Ropero, Ana Argibay, Joan Albert Barberá, Xavier Pla Salas, Amaya Martínez Meñaca, Ana Belén Madroñero Vuelta, Antonio Lara Padrón, Luis Sáez Comet, Juan Antonio Domingo Morera, Cristina González-Echávarri, Teresa Mombiela, Norberto Ortego-Centeno, Manuela Marín González, Carles Tolosa-Vilella, Isabel Blanco, Pilar Escribano Subías, Carmen Pilar Simeón-Aznar, RESCLE Consortium, REHAP Consortium
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/3de8cdeae3bb458dae6e4c1c0be7576f
Autor:
Diana Prieto-Peña, Fernanda Genre, Sara Remuzgo-Martínez, Verónica Pulito-Cueto, Belén Atienza-Mateo, Javier Llorca, Belén Sevilla-Pérez, Norberto Ortego-Centeno, Leticia Lera-Gómez, María Teresa Leonardo, Ana Peñalba, Javier Narváez, Luis Martín-Penagos, Emilio Rodrigo, José A. Miranda-Filloy, Luis Caminal-Montero, Paz Collado, Javier Sánchez Pérez, Diego de Argila, Esteban Rubio, Manuel León Luque, Juan María Blanco-Madrigal, Eva Galíndez-Agirregoikoa, Oreste Gualillo, Javier Martín, Santos Castañeda, Ricardo Blanco, Miguel A. González-Gay, Raquel López-Mejías
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/90dad8174dea42aabb16bad57e7b4770
Autor:
Sergio Burillo-Sanz, Marco-Antonio Montes-Cano, José-Raúl García-Lozano, Lourdes Ortiz-Fernández, Norberto Ortego-Centeno, Francisco-José García-Hernández, Gerard Espinosa, Genaro Graña-Gil, Juan Sánchez-Bursón, María Rosa Juliá, Roser Solans, Ricardo Blanco, Ana-Celia Barnosi-Marín, Ricardo Gómez De la Torre, Patricia Fanlo, Mónica Rodríguez-Carballeira, Luis Rodríguez-Rodríguez, Teresa Camps, Santos Castañeda, Juan-Jose Alegre-Sancho, Javier Martín, María Francisca González-Escribano
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Behçet’s disease (BD) is an immune-mediated systemic disorder with a well-established association with HLA class I and other genes. BD has clinical overlap with many autoinflammatory diseases (AIDs). The aim of this study was to investiga
Externí odkaz:
https://doaj.org/article/a17410930c33440f8760e7431d185c48
Autor:
Carl D. Langefeld, Hannah C. Ainsworth, Deborah S. Cunninghame Graham, Jennifer A. Kelly, Mary E. Comeau, Miranda C. Marion, Timothy D. Howard, Paula S. Ramos, Jennifer A. Croker, David L. Morris, Johanna K. Sandling, Jonas Carlsson Almlöf, Eduardo M. Acevedo-Vásquez, Graciela S. Alarcón, Alejandra M. Babini, Vicente Baca, Anders A. Bengtsson, Guillermo A. Berbotto, Marc Bijl, Elizabeth E. Brown, Hermine I. Brunner, Mario H. Cardiel, Luis Catoggio, Ricard Cervera, Jorge M. Cucho-Venegas, Solbritt Rantapää Dahlqvist, Sandra D’Alfonso, Berta Martins Da Silva, Iñigo de la Rúa Figueroa, Andrea Doria, Jeffrey C. Edberg, Emőke Endreffy, Jorge A. Esquivel-Valerio, Paul R. Fortin, Barry I. Freedman, Johan Frostegård, Mercedes A. García, Ignacio García de la Torre, Gary S. Gilkeson, Dafna D. Gladman, Iva Gunnarsson, Joel M. Guthridge, Jennifer L. Huggins, Judith A. James, Cees G. M. Kallenberg, Diane L. Kamen, David R. Karp, Kenneth M. Kaufman, Leah C. Kottyan, László Kovács, Helle Laustrup, Bernard R. Lauwerys, Quan-Zhen Li, Marco A. Maradiaga-Ceceña, Javier Martín, Joseph M. McCune, David R. McWilliams, Joan T. Merrill, Pedro Miranda, José F. Moctezuma, Swapan K. Nath, Timothy B. Niewold, Lorena Orozco, Norberto Ortego-Centeno, Michelle Petri, Christian A. Pineau, Bernardo A. Pons-Estel, Janet Pope, Prithvi Raj, Rosalind Ramsey-Goldman, John D. Reveille, Laurie P. Russell, José M. Sabio, Carlos A. Aguilar-Salinas, Hugo R. Scherbarth, Raffaella Scorza, Michael F. Seldin, Christopher Sjöwall, Elisabet Svenungsson, Susan D. Thompson, Sergio M. A. Toloza, Lennart Truedsson, Teresa Tusié-Luna, Carlos Vasconcelos, Luis M. Vilá, Daniel J. Wallace, Michael H. Weisman, Joan E. Wither, Tushar Bhangale, Jorge R. Oksenberg, John D. Rioux, Peter K. Gregersen, Ann-Christine Syvänen, Lars Rönnblom, Lindsey A. Criswell, Chaim O. Jacob, Kathy L. Sivils, Betty P. Tsao, Laura E. Schanberg, Timothy W. Behrens, Earl D. Silverman, Marta E. Alarcón-Riquelme, Robert P. Kimberly, John B. Harley, Edward K. Wakeland, Robert R. Graham, Patrick M. Gaffney, Timothy J. Vyse
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
Systemic lupus erythematosus (SLE) is an autoimmune disease with a strong ethnic and gender bias. In a transancestral genetic association study, Langefeldet al. identify 24 novel regions associated with risk to lupus and propose a cumulative hits hyp
Externí odkaz:
https://doaj.org/article/a68227bc3ba0457486591e4743061bf9