Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Norbert W. Paul"'
Autor:
Laura Holthöfer, Stefan Diederich, Verena Haug, Lioba Lehmann, Charlotte Hewel, Norbert W. Paul, Susann Schweiger, Susanne Gerber, Matthias Linke
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-8 (2024)
Abstract Adaptive nanopore sequencing as a diagnostic method for imprinting disorders and episignature analysis revealed an intragenic duplication of Exon 6 and 7 in UBE3A (NM_000462.5) in a patient with relatively mild Angelman-like syndrome. In an
Externí odkaz:
https://doaj.org/article/3d509ae199d648309382254570d89142
Publikováno v:
BMC Medical Ethics, Vol 25, Iss 1, Pp 1-6 (2024)
Abstract Despite clinical evidence of drug superiority, therapeutic modalities, like combination immunotherapy, are mostly considered cost-ineffective due to their high costs per life year(s) gained. This paper, taking an ethical stand, reevaluates t
Externí odkaz:
https://doaj.org/article/4072fc174e1a43a5b35fa55330868e48
Autor:
Susanne Tippmann, Janine Schäfer, Christine Arnold, Julia Winter, Norbert W. Paul, Eva Mildenberger, André Kidszun
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2024)
Background and objectiveObtaining informed consent in neonatal emergency research is challenging. The aim of this study was to assess parental perceptions of informed consent following participation in a clinical trial in neonatal emergency care.Meth
Externí odkaz:
https://doaj.org/article/0b67f3f2ce564fb6bfc8d80ecb75c2e2
Publikováno v:
Humanities, Vol 5, Iss 1, p 4 (2015)
Since the second half of the 20th century, the life sciences have become one of the dominant explanatory models for almost every aspect of human life. Hand in hand with biomedical developments and technologies, the life sciences are constantly shapin
Externí odkaz:
https://doaj.org/article/2ff24dac9add4c6db4eefd64c9438203
Autor:
Hamideh Mahdiani, Norbert W Paul
Publikováno v:
Clinical Ethics. 18:148-154
Novel immune therapies are increasingly based on the molecular differentiation of disease patterns. The related clinical studies are thus more often characterized by the so-called adaptive study designs (umbrella or basket studies including platform
Publikováno v:
Trends in Pharmacological Sciences. 43:998-1000
COVID-19 has put vaccine efficacy under a spotlight. However, the reluctance of people to be vaccinated has postponed the end of the COVID-19 pandemic. Currently, opioid vaccines are being developed, which could help prevent opioid addiction, overdos
Autor:
Thomas Efferth, Norbert W Paul
Publikováno v:
The Lancet Planetary Health, Vol 1, Iss 8, Pp e301-e303 (2017)
Externí odkaz:
https://doaj.org/article/5d7241c41f7d49a2bea56f8dfb1a4182
Autor:
Riccardo Haupt, Clarisa R. Gracia, Gabriele Calaminus, Jacqueline J. Loonen, Isabelle Demeestere, Kirsi Jahnukainen, Leontien C. M. Kremer, Barbara A. Lockart, Hanneke M van Santen, Karen Burns, Wim J. E. Tissing, Richard N. Yu, Eva Maria Tinner, Louis S. Constine, Thorsten Langer, Ogechukwu A Asogwa, W. Hamish B. Wallace, Sebastian J C M M Neggers, Erik A. H. Loeffen, Marianne D. van de Wetering, Sarah E Hunter, Margreet A. Veening, Lisa B. Kenney, Julianne Byrne, Claire Berger, Joanne Frankel Kelvin, Natascia Di Iorgi, Roderick Skinner, Ans M M van Pelt, Daniel M. Green, Richard A Anderson, Holly R. Hoefgen, Marij Dinkelman-Smit, Herman Tournaye, Eveline Stutz-Grunder, Marleen van de Berg, Andreas Ranft, Chris M Verhaak, Christian Denzer, Andrica de Vries, Kenny A. Rodriguez-Wallberg, Michelle Peate, Lillian R. Meacham, Joop S.E. Laven, Renée L. Mulder, Rejin Kebudi, Cornelis B. Lambalk, Anna Font-Gonzalez, Norbert W Paul, Jennifer Levine, Rod T. Mitchell, Catharyn Stern, Eline van Dulmen-den Broeder, Tamara Diesch, James L. Klosky, Antoinette Anazodo, Armando Lorenzo, Annelies M E Bos, Desiree Grabow, Wendy van Dorp, Andreas Meissner, Uta Dirksen, Gwendolyn P. Quinn, Melissa M. Hudson, Bob Phillips, Damon R. Reed, Aleksander Giwercman, Julia Inthorn, Marry M. van den Heuvel-Eibrink, J. D. Beck, Leena Nahata, Alexandra Brownsdon, Peter Kaatsch, Anke Barnbrock, Jill P. Ginsberg
Publikováno v:
PanCareLIFE Consortium 2021, ' Communication and ethical considerations for fertility preservation for patients with childhood, adolescent, and young adult cancer : recommendations from the PanCareLIFE Consortium and the International Late Effects of Childhood Cancer Guideline Harmonization Group ', The Lancet Oncology, vol. 22, no. 2, pp. e68-e80 . https://doi.org/10.1016/S1470-2045(20)30595-7
The Lancet Oncology, 22(2), e68-e80. Lancet Publishing Group
The Lancet Oncology, 22(2), e68-e80. Lancet Publishing Group
Patients with childhood, adolescent, and young adult cancer who will be treated with gonadotoxic therapies are at increased risk for infertility. Many patients and their families desire biological children but effective communication about treatment-
Autor:
Norbert W. Paul
Publikováno v:
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
ZusammenfassungNeue Immuntherapien werden aufgrund der immer weiter reichenden molekularen Differenzierung von Erkrankungsmustern immer häufiger in sogenannten adaptiven, also fortlaufend an Ergebnisse angepassten Studiendesigns (Umbrella- oder Bask
Publikováno v:
Bioethics. 36(2)