Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Norbert Volkmar"'
Autor:
Yuming Jiang, Devasahayam Arokia Balaya Rex, Dina Schuster, Benjamin A. Neely, Germán L. Rosano, Norbert Volkmar, Amanda Momenzadeh, Trenton M. Peters-Clarke, Susan B. Egbert, Simion Kreimer, Emma H. Doud, Oliver M. Crook, Amit Kumar Yadav, Muralidharan Vanuopadath, Adrian D. Hegeman, Martín L. Mayta, Anna G. Duboff, Nicholas M. Riley, Robert L. Moritz, Jesse G. Meyer
Publikováno v:
ACS Measurement Science Au, Vol 4, Iss 4, Pp 338-417 (2024)
Externí odkaz:
https://doaj.org/article/77b50bdc366d4ecc8281c0455ca0c0c7
Autor:
Anna S. Dickson, Tekle Pauzaite, Esther Arnaiz, Brian M. Ortmann, James A. West, Norbert Volkmar, Anthony W. Martinelli, Zhaoqi Li, Niek Wit, Dennis Vitkup, Arthur Kaser, Paul J. Lehner, James A. Nathan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Cholesterol biosynthesis is a highly regulated, oxygen-dependent pathway, vital for cell membrane integrity and growth. In fungi, the dependency on oxygen for sterol production has resulted in a shared transcriptional response, resembling pr
Externí odkaz:
https://doaj.org/article/c87d491caba847fcaeae18fb670de9f1
Autor:
Anna S. Dickson, Tekle Pauzaite, Esther Arnaiz, Brian M. Ortmann, James A. West, Norbert Volkmar, Anthony W. Martinelli, Zhaoqi Li, Niek Wit, Dennis Vitkup, Arthur Kaser, Paul J. Lehner, James A. Nathan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/1e8df5e5952f458ba4cea0c1b5668fea
Autor:
Anna S. Dickson, Tekle Pauzaite, Esther Arnaiz, Brian M. Ortmann, James A. West, Norbert Volkmar, Anthony W. Martinelli, Zhaoqi Li, Niek Wit, Dennis Vitkup, Arthur Kaser, Paul J. Lehner, James A. Nathan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/2599fb5071604775b7eff4fa0c444bd5
Autor:
Sam A Menzies, Norbert Volkmar, Dick JH van den Boomen, Richard T Timms, Anna S Dickson, James A Nathan, Paul J Lehner
Publikováno v:
eLife, Vol 7 (2018)
Mammalian HMG-CoA reductase (HMGCR), the rate-limiting enzyme of the cholesterol biosynthetic pathway and the therapeutic target of statins, is post-transcriptionally regulated by sterol-accelerated degradation. Under cholesterol-replete conditions,
Externí odkaz:
https://doaj.org/article/f84da21acd8c46149f6d640a9199b032
Autor:
Anna Pagotto, Otavia L Caballero, Norbert Volkmar, Sylvie Devalle, Andrew J G Simpson, Xin Lu, John C Christianson
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83212 (2013)
The Cancer/Testis (CT) antigen family of genes are transcriptionally repressed in most human tissues but are atypically re-expressed in many malignant tumour types. Their restricted expression profile makes CT antigens ideal targets for cancer immuno
Externí odkaz:
https://doaj.org/article/79f3c41ea5c74f1a919cb98eb44a6c04
Autor:
Anna Dickson, Tekle Pauzaite, Esther Arnaiz, Brian Ortmann, James West, Norbert Volkmar, Anthony Martinelli, Zhaoqi Li, Niek Wit, Dennis Vitkup, Arthur Kaser, Paul Lehner, James Nathan
Cholesterol biosynthesis is a highly regulated, oxygen-dependent pathway, vital for cell membrane integrity and growth. In fungi, the dependency on oxygen for sterol production has resulted in a shared transcriptional response, resembling prolyl hydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa9ec80cc62ffca30e87333f4867a204
https://doi.org/10.21203/rs.3.rs-2579549/v1
https://doi.org/10.21203/rs.3.rs-2579549/v1
Autor:
Norbert Volkmar, Christian M Gawden‐Bone, James C Williamson, Jonathon Nixon‐Abell, James A West, Peter H St George‐Hyslop, Arthur Kaser, Paul J Lehner
Publikováno v:
The EMBO Journal. 41
The regulation of membrane lipid composition is critical for cellular homeostasis. Cells are particularly sensitive to phospholipid saturation, with increased saturation causing membrane rigidification and lipotoxicity. How mammalian cells sense memb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::225531fb739db0584e23c6de3aed0bb5
https://doi.org/10.15252/embj.2022110777
https://doi.org/10.15252/embj.2022110777
Publikováno v:
Current Opinion in Cell Biology. 65:103-111
Cholesterol is an essential component of mammalian membranes, and its homeostasis is strictly regulated, with imbalances causing atherosclerosis, Niemann Pick disease, and familial hypercholesterolemia. Cellular cholesterol supply is mediated by LDL-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b241f5871b5fe27af964aff0bf8b8b5
https://doi.org/10.1016/j.ceb.2020.04.010
https://doi.org/10.1016/j.ceb.2020.04.010