Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Norbert Sule"'
Autor:
Kinga Szigeti, Ivanna Ihnatovych, Emily Notari, Ryu P. Dorn, Ivan Maly, Muye He, Barbara Birkaya, Shreyas Prasad, Robin Schwartz Byrne, Dinesh C. Indurthi, Erik Nimmer, Yuna Heo, Kolos Retfalvi, Lee Chaves, Norbert Sule, Wilma A. Hofmann, Anthony Auerbach, Gregory Wilding, Yongho Bae, Jessica Reynolds
Publikováno v:
EBioMedicine, Vol 103, Iss , Pp 105093- (2024)
Summary: Background: Human restricted genes contribute to human specific traits in the immune system. CHRFAM7A, a uniquely human fusion gene, is a negative regulator of the α7 nicotinic acetylcholine receptor (α7 nAChR), the highest Ca2+ conductor
Externí odkaz:
https://doaj.org/article/253d4e81484540ca907db9935ccfbe93
Autor:
Shruti D. Shah, Bryan M. Gillard, Michelle M. Wrobel, Ellen Karasik, Michael T. Moser, Michalis Mastri, Mark D. Long, Norbert Sule, Craig M. Brackett, Wendy J. Huss, Barbara A. Foster
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionBladder cancer is a heterogenous disease and the emerging knowledge on molecular classification of bladder tumors may impact treatment decisions based on molecular subtype. Pre-clinical models representing each subtype are needed to test
Externí odkaz:
https://doaj.org/article/4ca92263d3fb4dc7be3b998b093ff868
Autor:
Kinga Szigeti, Ivanna Ihnatovych, Barbara Birkaya, Ziqiang Chen, Aya Ouf, Dinesh C. Indurthi, Jonathan E. Bard, Julien Kann, Alexandrea Adams, Lee Chaves, Norbert Sule, Joan S. Reisch, Valory Pavlik, Ralph H.B. Benedict, Anthony Auerbach, Gregory Wilding
Publikováno v:
EBioMedicine, Vol 59, Iss , Pp 102892- (2020)
Background: Cholinergic neuronal loss is one of the hallmarks of AD related neurodegeneration; however, preclinical promise of α7 nAChR drugs failed to translate into humans. CHRFAM7A, a uniquely human fusion gene, is a negative regulator of α7 nAC
Externí odkaz:
https://doaj.org/article/6f7ea999104a48eb91f60c5ad0633972
Autor:
Shruti D Shah, Bryan M Gillard, Michelle M Wrobel, Ellen Karasik, Michael T Moser, Michalis Mastri, Norbert Sule, Craig M Brackett, Wendy J Huss, Barbara A Foster
BackgroundBladder cancer is a heterogenous disease and the emerging knowledge on molecular classification of bladder tumors could have impact to drive treatment decisions based on molecular subtype. Pre-clinical models representing each subtype are n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8a504ed4d073fb5344dd75d40acf91c
https://doi.org/10.1101/2022.12.03.518865
https://doi.org/10.1101/2022.12.03.518865
Autor:
Éva Kocsmár, Tamas Beothe, Péter Nyirády, Gábor Lotz, Gábor Pajor, Márton Varga, Attila Szendrői, Norbert Sule, Attila Majoros, András Kiss, Eszter Székely, István Kenessey, Péter Riesz, Benedek Gyöngyösi, Ildikó Kocsmár
Publikováno v:
American journal of clinical pathology. 153(2)
Objectives Our aim was to predict progression of non-muscle-invasive bladder urothelial carcinomas (NMIUCs) into muscle-invasive disease by assessing cytogenetic abnormality of tumors with a new UroVysion scoring system. Methods Seventy-five bladder
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f29bcba9b227fc1eab69fa970270f308
https://pubmed.ncbi.nlm.nih.gov/31732739
https://pubmed.ncbi.nlm.nih.gov/31732739
Autor:
Anthony Auerbach, Tapan K. Nayak, Ivanna Ihnatovych, Lee D. Chaves, Kinga Szigeti, Barbara Birkaya, Norbert Sule, Aya Ouf
Publikováno v:
Translational Psychiatry, Vol 9, Iss 1, Pp 1-11 (2019)
Translational Psychiatry
Translational Psychiatry
The α7 nicotinic acetylcholine receptor (α7nAChR) has been a promising target for diseases affecting cognition and higher cortical functions; however, the effect observed in animal models failed to translate into human clinical trials identifying a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06cf93660087ee990000f7f6636fd8d4
https://doi.org/10.1038/s41398-019-0375-z
https://doi.org/10.1038/s41398-019-0375-z
Autor:
Rachel Nathan, Angie Elefante, Norbert Sule, Marcus Sikorski, Saby George, Jordan Cinquino, Dennis A. Buck, Andrew J. Fabiano, Laurie Herbst, Taha Bat
Publikováno v:
Urology. 131
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee5641d1787a1193db749c7d2599ec9f
https://pubmed.ncbi.nlm.nih.gov/31059726
https://pubmed.ncbi.nlm.nih.gov/31059726
Autor:
Christine Murekeyisoni, Gissou Azabdaftari, Norbert Sule, Kristopher Attwood, Michael Vacchio, James L. Mohler, Eric C. Kauffman, Chirag Doshi, Diana Mehedint, Khurshid A. Guru, Shervin Badkhshan
Publikováno v:
The Prostate. 76:715-721
OBJECTIVE To determine the oncologic impact of prospectively assigned tertiary pattern 4 in contemporary Gleason score (GS) 3 + 3 = 6 radical prostatectomy (RP) specimens. PATIENTS AND METHODS Oncologic outcomes were retrospectively reviewed for 720
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4789067d55f45fc380f3528110230b72
https://doi.org/10.1002/pros.23166
https://doi.org/10.1002/pros.23166
Autor:
Ivanna Ihnatovych, Gregory E. Wilding, Anthony Auerbach, Dinesh C. Indurthi, Barbara Birkaya, Alexandrea Adams, Norbert Sule, Julien Kann, Lee D. Chaves, Kinga Szigeti, Ralph H.B. Benedict, Ziqiang Chen, Valory N. Pavlik, Aya Ouf, Jonathan E. Bard, Joan S. Reisch
Publikováno v:
EBioMedicine
EBioMedicine, Vol 59, Iss, Pp 102892-(2020)
EBioMedicine, Vol 59, Iss, Pp 102892-(2020)
Background Cholinergic neuronal loss is one of the hallmarks of AD related neurodegeneration; however, preclinical promise of α7 nAChR drugs failed to translate into humans. CHRFAM7A, a uniquely human fusion gene, is a negative regulator of α7 nACh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0702750a6b0ee92d4f2e2cc92b1ef8f4
https://doi.org/10.1016/j.ebiom.2020.102892
https://doi.org/10.1016/j.ebiom.2020.102892
Autor:
Norbert Sule, Diping Wang
Publikováno v:
Archives of pathologylaboratory medicine. 143(2)
Urachal neoplasms are uncommon and represent a minor portion of bladder tumors. According to the recently updated World Health Organization classification (2016), these tumors are classified as adenomas, adenocarcinomas, nonglandular neoplasms, and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eb6fa4e6beec28973e593d570bd0dd2
https://pubmed.ncbi.nlm.nih.gov/30398914
https://pubmed.ncbi.nlm.nih.gov/30398914