Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Norbert P. LeClair"'
Autor:
Jordan W. Tappero, Emmanuel Arinaitwe, Melissa D. Conrad, Norbert P. LeClair, Abel Kakuru, Philip J. Rosenthal, Humphrey Wanzira, Victor Bigira, Mary K. Muhindo, Moses R. Kamya, Bryan Greenhouse, Grant Dorsey
Publikováno v:
The Journal of infectious diseases, vol 210, iss 3
(See the editorial commentary by Taylor and Juliano on pages 335–7.) Artemisinin-based combination therapies (ACTs) have shown excellent efficacy and are now recommended to treat falciparum malaria in nearly all countries [1]. ACTs include potent,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::560b8ca56224f203bb1aa08b0b2d2c4b
https://doi.org/10.1093/infdis/jiu141
https://doi.org/10.1093/infdis/jiu141
Autor:
Samuel L. Nsobya, Melissa D. Conrad, Philip J. Rosenthal, Frederick N. Baliraine, Christian Nsanzabana, Norbert P. LeClair
Publikováno v:
Journal of clinical microbiology, vol 51, iss 8
Genetic polymorphisms in the malaria parasite Plasmodium falciparum mediate alterations in sensitivity to important antimalarial drugs. Surveillance for these polymorphisms is helpful in assessing the prevalence of drug resistance and designing strat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26de7859e159038506366f68643a94ba
https://doi.org/10.1128/jcm.00904-13
https://doi.org/10.1128/jcm.00904-13
Autor:
Jason DeVoss, Wen Lu, Lawrence Fong, Norbert P. LeClair, Navdeep K. Grewal, Yafei Hou, Mark S. Anderson, Kellsey Johannes, Ting Yang, Craig Meagher, Erich C. Strauss
Publikováno v:
The Journal of Immunology. 184:4236-4246
Sjögren’s Syndrome (SS) is a human autoimmune disease characterized by immune-mediated destruction of the lacrimal and salivary glands. In this study, we show that the Aire-deficient mouse represents a new tool to investigate autoimmune dacryoaden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bd07cba5126e7bdf17cb8e536bc1c29
https://doi.org/10.4049/jimmunol.0902434
https://doi.org/10.4049/jimmunol.0902434
Autor:
Anthony K. Shum, Mark S. Anderson, Cecilia Austin, Wen Lu, Erich C. Strauss, Jason DeVoss, Anna K. Krawisz, Kellsey Johannes, Ting Yang, Peter L. Wang, Norbert P. LeClair
Publikováno v:
The Journal of Immunology. 181:4072-4079
Mutations in the Aire gene result in a clinical phenomenon known as Autoimmune Polyglandular Syndrome (APS) Type I, which classically manifests as a triad of adrenal insufficiency, hypoparathyroidism, and chronic mucocutaneous infections. In addition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2674840553a8122d4f0eda2ed91fb645
https://doi.org/10.4049/jimmunol.181.6.4072
https://doi.org/10.4049/jimmunol.181.6.4072
Autor:
Philip J. Rosenthal, Roland A. Cooper, Samuel L. Nsobya, Melissa D. Conrad, Jessica Bloome, Benjamin Kozak, Moses R. Kamya, Diane V. Havlir, Abel Kakuru, Oswald Byaruhanga, Victor Bigira, Jiri Gut, Jennifer Legac, Norbert P. LeClair, Bryan Greenhouse, James Kapisi, Jaffer Okiring, Grant Dorsey, Patrick K Tumwebaze, Andrew Walakira, Christine Nakazibwe
Publikováno v:
Antimicrobial agents and chemotherapy, vol 59, iss 6
Changing treatment practices may be selecting for changes in the drug sensitivity of malaria parasites. We characterized ex vivo drug sensitivity and parasite polymorphisms associated with sensitivity in 459 Plasmodium falciparum samples obtained fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf3079748096ea9a52ce4dd7b6b643a5
https://pubmed.ncbi.nlm.nih.gov/25753626
https://pubmed.ncbi.nlm.nih.gov/25753626
Autor:
Sheila Nankoberanyi, Jordan W. Tappero, Samuel L. Nsobya, Philip J. Rosenthal, Melissa D. Conrad, Norbert P. LeClair, George W Mbogo, Patrick K Tumwebaze, Stephen Tukwasibwe, Moses R. Kamya
Publikováno v:
Malaria Journal
Background Malaria remains a major public health problem, and its control has been hampered by drug resistance. For a number of drugs, Plasmodium falciparum single nucleotide polymorphisms (SNPs) are associated with altered drug sensitivity and can b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb6f3175a975215273c43171952cb86f
https://doi.org/10.1186/1475-2875-13-95
https://doi.org/10.1186/1475-2875-13-95