Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Norbert Kučerka"'
Autor:
Anne M. Kiirikki, Hanne S. Antila, Lara S. Bort, Pavel Buslaev, Fernando Favela-Rosales, Tiago Mendes Ferreira, Patrick F. J. Fuchs, Rebeca Garcia-Fandino, Ivan Gushchin, Batuhan Kav, Norbert Kučerka, Patrik Kula, Milla Kurki, Alexander Kuzmin, Anusha Lalitha, Fabio Lolicato, Jesper J. Madsen, Markus S. Miettinen, Cedric Mingham, Luca Monticelli, Ricky Nencini, Alexey M. Nesterenko, Thomas J. Piggot, Ángel Piñeiro, Nathalie Reuter, Suman Samantray, Fabián Suárez-Lestón, Reza Talandashti, O. H. Samuli Ollila
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Tools based on artificial intelligence (AI) are currently revolutionising many fields, yet their applications are often limited by the lack of suitable training data in programmatically accessible format. Here we propose an effective solutio
Externí odkaz:
https://doaj.org/article/acfa193917a24cbab8ffde269f7d7c0d
Autor:
Ferdinand Fandrei, Tomáš Havrišák, Lukáš Opálka, Oskar Engberg, Albert A. Smith, Petra Pullmannová, Norbert Kučerka, Veronika Ondrejčeková, Bruno Demé, Lucie Nováková, Miloš Steinhart, Kateřina Vávrová, Daniel Huster
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 5, Pp 100356- (2023)
Omega-O-acyl ceramides such as 32-linoleoyloxydotriacontanoyl sphingosine (Cer[EOS]) are essential components of the lipid skin barrier, which protects our body from excessive water loss and the penetration of unwanted substances. These ceramides dri
Externí odkaz:
https://doaj.org/article/d2014d3735294b249f6d211ee7a94412
Autor:
Oleksandr Ivankov, Tatiana N. Murugova, Elena V. Ermakova, Tomáš Kondela, Dina R. Badreeva, Pavol Hrubovčák, Dmitry Soloviov, Alexey Tsarenko, Andrey Rogachev, Alexander I. Kuklin, Norbert Kučerka
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract The amyloid-beta peptide (Aβ) is considered a key factor in Alzheimer's disease (AD) ever since the discovery of the disease. The understanding of its damaging influence has however shifted recently from large fibrils observed in the inter-
Externí odkaz:
https://doaj.org/article/adfdcfbc3380435eb0ef46ee69ca3ce8
Autor:
Sergei Kurakin, Oleksandr Ivankov, Vadim Skoi, Alexander Kuklin, Daniela Uhríková, Norbert Kučerka
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Combining small-angle neutron scattering (SANS), small-angle X-ray scattering (SAXS), and densitometric measurements, we have studied the interactions of the divalent cations Ca2+ and Mg2+ with the lipid vesicles prepared of a mixed-chain palmitoyl-o
Externí odkaz:
https://doaj.org/article/2e7c096f34fc46758a0fbe37fbb13a7e
Autor:
Petra Pullmannová, Elena Ermakova, Andrej Kováčik, Lukáš Opálka, Jaroslav Maixner, Jarmila Zbytovská, Norbert Kučerka, Kateřina Vávrová
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 5, Pp 963-971 (2019)
Membrane models of the stratum corneum (SC) lipid barrier, either healthy or affected by recessive X-linked ichthyosis, constructed from ceramide [Cer; nonhydroxyacyl sphingosine N-tetracosanoyl-d-erythro-sphingosine (CerNS24) alone or with omega-O-a
Externí odkaz:
https://doaj.org/article/ea4584eac098420fb349a0b5aa2e5013
Publikováno v:
Membranes, Vol 5, Iss 3, Pp 454-472 (2015)
We review recent developments in the rapidly growing field of membrane biophysics, with a focus on the structural properties of single lipid bilayers determined by different scattering techniques, namely neutron and X-ray scattering. The need for acc
Externí odkaz:
https://doaj.org/article/33885050cae544539051779cc871edfc
Autor:
Tomáš Kondela, Jana Gallová, Thomas Hauß, Jonathan Barnoud, Siewert-J. Marrink, Norbert Kučerka
Publikováno v:
Molecules, Vol 22, Iss 12, p 2078 (2017)
We investigate the structural changes to lipid membrane that ensue from the addition of aliphatic alcohols with various alkyl tail lengths. Small angle neutron diffraction from flat lipid bilayers that are hydrated through water vapor has been employ
Externí odkaz:
https://doaj.org/article/1386880d12db4a228432b5cff5b62b1c
Autor:
Horia I. Petrache, Stephanie Tristram-Nagle, Daniel Harries, Norbert Kučerka, John F. Nagle, V. Adrian Parsegian
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 2, Pp 302-309 (2006)
Critical to biological processes such as membrane fusion and secretion, ion-lipid interactions at the membrane-water interface still raise many unanswered questions. Using reconstituted phosphatidylcholine membranes, we confirm here that multilamella
Externí odkaz:
https://doaj.org/article/ac2493e13d24425b8745a479a34bd96d
Autor:
Clare L Armstrong, Drew Marquardt, Hannah Dies, Norbert Kučerka, Zahra Yamani, Thad A Harroun, John Katsaras, An-Chang Shi, Maikel C Rheinstädter
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66162 (2013)
Rafts, or functional domains, are transient nano- or mesoscopic structures in the exoplasmic leaflet of the plasma membrane, and are thought to be essential for many cellular processes. Using neutron diffraction and computer modelling, we present evi
Externí odkaz:
https://doaj.org/article/a2f20a1d6f384578a4ca65ca8631e683
Autor:
Matthew A Barrett, Songbo Zheng, Golnaz Roshankar, Richard J Alsop, Randy K R Belanger, Chris Huynh, Norbert Kučerka, Maikel C Rheinstädter
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34357 (2012)
We studied the interaction of Aspirin (acetylsalicylic acid) with lipid membranes using x-ray diffraction for bilayers containing up to 50 mol% of aspirin. From 2D x-ray intensity maps that cover large areas of reciprocal space we determined the posi
Externí odkaz:
https://doaj.org/article/d01dee1dcc0e442a9595ba51aa0221cf