Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Norbert Krass"'
1
Synthesis of HR 916 K: An Efficient Route to the Pure Diastereomers of the 1-(Pivaloyloxy)ethyl Esters of Cephalosporins
Autor: Norbert Krass, Dieter Isert, Rolf Horlein, Fischer Gerd, Theo Wollmann, Uwe Gerlach, Ulrich Stache, Elisabeth Defoßa, Rudolf Lattrell
Publikováno v: Liebigs Annalen. 1996:1743-1749
HR 916 K (5), the 1-(S)-(pivaloyloxy)ethyl prodrug ester of the cephalosporin cefdaloxime, exhibits a significantly higher oral bioavailability than the 1-(R) diastereomer HR 916 J. An efficient synthesis of HR 916 K was developed. The separation of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7ced9b6c375c1c441b4b7c9c015448a6
https://doi.org/10.1002/jlac.199619961107
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2
Optically active oxazolidinones as Michael donors for the short and efficient synthesis of β-amino acids containing a cyclopropane ring
Autor: Albert I. Meyers, Armin de Meijere, Norbert Krass, Corinna Gratkowski, M. Es‐Sayed
Publikováno v: Tetrahedron Letters. 34:289-292
The Michael addition of optically active 3, 4-diphenyloxazolidinone 5 to 2′-substituted 2-chloro-2-cyclopropylideneacetates yields 2′-substituted 2-cyclopropyl-1′-(2-oxo-3, 4-diphenyloxazolidin-3-yl)acetates 6-R with excellent trans-selectivity
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6479ab477258ae058535a4f0978c484b
https://doi.org/10.1016/s0040-4039(00)60569-5
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4
A New Versatile Synthesis of Ring‐Substituted 2‐Cyclopropylglycines and Related Amino Acids
Autor: Dahai Yu, Norbert Krass, Armin de Meijere, Ludger A. Wessjohann
Publikováno v: Chemische Berichte. 125:867-882
Alkyl 2-chloro-2-cyclopropylideneacetates 2 serve as universal starting materials for a new general synthesis of cyclopro-pylglycines by a simple three- to four-step methodology. 1,4-Addition of nucleophiles, substitution with azide ion, and mild cat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f8968ac8c7597ae3cf3128c1570a046a
https://doi.org/10.1002/cber.19921250418
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8
Cyclopropyl Group Containing Amino Acids From α-Chlorocyclopropylidenacetates
Autor: Norbert Krass, Dahai Yu, Ludger A. Wessjohann, Armin de Meijere
Publikováno v: Strain and Its Implications in Organic Chemistry ISBN: 9789401069076
Cyclopropane amino acids have attracted the attention of synthetically and biologically oriented chemists throughout the last decade. Most efforts have been directed towards 1-aminocyclopropane carboxyclic acid (ACC), the natural precursor of the phy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1f335e137ab26ea90588447fea6e5305
https://doi.org/10.1007/978-94-009-0929-8_42
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