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of 30
pro vyhledávání: '"Norbert Kolassa"'
Autor:
Norbert Kolassa
Publikováno v:
Regulatory Toxicology and Pharmacology. 65:115-118
The European Medicines Agency concluded that there is a risk of suppositories containing terpenic derivatives, which are used to treat coughs and colds, inducing neurological disorders, especially convulsions, in infants and small children. Terpenic
Autor:
Rodolfo Testa, Karl Sanders, Rainer Boer, Norbert Kolassa, Wolf-Rüdiger Ulrich, Peter Hein, Manfrid Eltze, Martin C. Michel
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 363:649-662
We have investigated the pharmacological properties of B8805-033 [(+/-)- 1,3,5-trimethyl-6-[[3-[4-((2,3-dihydro-2-hydroxymethyl)-1,4-benzodioxin-5-yl)-1-piperazinyl]propyl] amino]-2,4(1H,3H)-pyrimidinedione], a new alpha1A-adrenoceptor (AR) selective
Publikováno v:
Journal of Cardiovascular Pharmacology. 15:S86-S93
Autor:
Manfred Göthert, Norbert Kolassa
Publikováno v:
Journal of Cardiovascular Pharmacology. 15:i-v
Publikováno v:
European journal of pharmacology. 202(1)
The vasodilator mechanism of the putative serotonin 1A (5-HT) receptor agonists, urapidil, 5-methyl-urapidil, ipsapirone. flesinoxan and 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) was investigated in constant-pressure perfused rat kidneys. Th
Publikováno v:
The American Journal of Cardiology. 64:D7-D10
Stimulation of serotonin-1A (5-hydroxytryptamine) (5-HT1A) receptors in the brain stem has been suggested to contribute to the antihypertensive action of the alpha 1-adrenoceptor antagonist urapidil. This hypothesis was tested by analyzing the influe
Publikováno v:
European Journal of Biochemistry. 92:349-359
Phosphorylation of the calcium-transport ATPase of skeletal muscle sarcoplasmic reticulum by inorganic phosphate was investigated in the presence or absence of a calcium gradient. The maximum phosphoprotein formation in the presence of a calcium grad
Publikováno v:
Pfl�gers Archiv European Journal of Physiology. 365:197-202
In isolated K+ (16.2 mM)-arrested cat hearts perfused at constant pressure adenosine infusions (0.8 mumoles - min-1 - 100 g-1 for 10 min) caused an increase in myocardial 14C-glucose uptake and release of 14CO2 + H14CO3- AND 14C-lactate simultaneousl
Autor:
Alan R. P. Paterson, Norbert Kolassa
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 60:167-173
Mouse livers were perfused at 22 °C with an oxygenated salts medium containing [5−3H]cytidine and [carboxyl-14C]inulin. The cellular uptake of cytidine was determined from the 3H content of liver samples less that present in the extracellular (inu
Publikováno v:
The American Journal of Cardiology. 63:C36-C39
Current knowledge about the role of serotonin (5-HT) in central cardiovascular regulation is reviewed. Results from experiments with the 5-HT 1A receptor agonist 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT) suggest that activation of somatoden