Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Norbert Kienzle"'
Publikováno v:
European Journal of Immunology. 46:863-873
While the functional plasticity of memory CD4(+) T cells has been studied extensively, less is known about this property in memory CD8(+) T cells. Here, we report the direct measurement of plasticity by paired daughter analysis of effector and memory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce7f774db8fbd16acfa1deed79dbde2d
https://doi.org/10.1002/eji.201545726
https://doi.org/10.1002/eji.201545726
Autor:
Stephanie H Lim, Paul de Souza, Annette Tognela, Therese M. Becker, Norbert Kienzle, Nicole J. Caixeiro, Kevin J. Spring, Kieran F. Scott
Publikováno v:
International Journal of Cancer. 134:2523-2533
Circulating tumor cells (CTCs) are now routinely isolated from blood, and measurement of CTC concentrations appears to correlate well with survival in patients with cancer. Interrogation of the molecular profile of CTCs for expression of protein biom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1331a13e258acd4624399ca4c60f3d8
https://doi.org/10.1002/ijc.28516
https://doi.org/10.1002/ijc.28516
Autor:
Adriana Baz, Penny L. Groves, Stuart D. Olver, Simon H. Apte, Anne Kelso, Norbert Kienzle, Denise L. Doolan
Publikováno v:
The Journal of Immunology. 185:998-1004
Activation of naive CD8 T cells in vitro in the presence of IL-4 induces type 2 cytokine expression, loss of CD8 expression, and reduced cytolytic potential. This represents a major shift from the canonical phenotype of effector CD8 T cells. It has n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b7daa34b4745f97021a1c8b8ef2dc23
https://doi.org/10.4049/jimmunol.0903372
https://doi.org/10.4049/jimmunol.0903372
Autor:
Anne Kelso, Michelle L. Janas, Norbert Kienzle, Stuart D. Olver, Kathy Buttigieg, Edward S. Morris, Penny Groves
Publikováno v:
Cancer Research. 66:571-580
An interleukin (IL)-4-containing tumor environment is reported to be beneficial for immune clearance of tumor cells in vivo; however, the effect of IL-4 on the effector CD8+ T cells contributing to tumor clearance is not well defined. We have used th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3ab848337440067b4ed2579662ad588
https://doi.org/10.1158/0008-5472.can-05-1362
https://doi.org/10.1158/0008-5472.can-05-1362
Publikováno v:
The Journal of Immunology. 175:8003-8010
Perforin and the serine protease granzymes are key effectors of CD8+ T cell granule-mediated cytotoxicity, but the requirements for their expression remain largely undefined. We show in this study that IL-2 increased the expression of perforin and gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::506fcc6857b207d93bc709ce7500ddea
https://doi.org/10.4049/jimmunol.175.12.8003
https://doi.org/10.4049/jimmunol.175.12.8003
Autor:
Steven A. Porcelli, Kelli P. A. MacDonald, Helen M. Bofinger, Rachel D. Kuns, Alistair L. J. Don, Dale I. Godfrey, Stuart D. Olver, Daniel G. Pellicci, Angela C. Burman, Vanessa Rowe, Norbert Kienzle, Tatjana Banovic, Geoffrey R. Hill, Mark J. Smyth, Edward S. Morris
Publikováno v:
Journal of Clinical Investigation. 115:3093-3103
NKT cells have pivotal roles in immune regulation and tumor immunosurveillance. We report that the G-CSF and FMS-like tyrosine kinase 3 ligand (Flt-3L) chimeric cytokine, progenipoietin-1, markedly expands the splenic and hepatic NKT cell population
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcffd9103e96012db3cfe4d2edbeb77d
https://doi.org/10.1172/jci25249
https://doi.org/10.1172/jci25249
Publikováno v:
The Journal of Immunology. 168:1672-1681
Immune deviation of cytolytic T cell function, induced by type 2 cytokines like IL-4, is an attractive concept to explain failure of the immune system in some diseases. However, this concept is challenged by previous conflicting results on whether ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2824f5c52435d7fec1edff1301613989
https://doi.org/10.4049/jimmunol.168.4.1672
https://doi.org/10.4049/jimmunol.168.4.1672
Autor:
Stephanie H Lim, Annette Tognela, Kevin J. Spring, Therese M. Becker, Kieran F. Scott, P. de Souza, Norbert Kienzle, Nicole J. Caixeiro
Publikováno v:
Cancer metastasis reviews. 33(2-3)
Circulating tumour cells (CTCs) are emerging as important prognostic markers and have potential clinical utility as tumour biomarkers for targeted cancer therapy. Although CTCs were proposed more than 100 years ago as potential precursors that may fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7822d1054698fbfca09ec7e73e900e6b
https://pubmed.ncbi.nlm.nih.gov/24817039
https://pubmed.ncbi.nlm.nih.gov/24817039
Publikováno v:
Burns. 27:179-182
Chryseobacteria are gram negative organisms, formerly known as Flavobacteria, which rarely cause infections of burn wounds. This article documents three cases of Chryseobacterium infection in burn wounds and adds to the other two cases that have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bfc4a649cd181eaaa2f05841017e416
https://doi.org/10.1016/s0305-4179(00)00087-5
https://doi.org/10.1016/s0305-4179(00)00087-5
Publikováno v:
Journal of Virology. 73:8902-8906
The cellular localization of the Epstein-Barr virus-encoded RK-BARF0 protein was analyzed by fluorescence microscopy and immunoblotting. The recombinant RK-BARF0 protein was found to be tightly bound to nuclear structures, whereas 16- to 20-kDa RK-BA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ae56a013b0f807f821d3f43d73e72bb
https://doi.org/10.1128/jvi.73.10.8902-8906.1999
https://doi.org/10.1128/jvi.73.10.8902-8906.1999