Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Norbert, Szoboszlai"'
Autor:
Balázs Vári, Levente Dókus, Adina Borbély, Anikó Gaál, Diána Vári-Mező, Ivan Ranđelović, Anna Sólyom-Tisza, Zoltán Varga, Norbert Szoboszlai, Gábor Mező, József Tóvári
Publikováno v:
Drug Delivery, Vol 30, Iss 1 (2023)
AbstractChemotherapy is still a leading therapeutic approach in various tumor types that is often accompanied by a poor prognosis because of metastases. PEGylated liposomes with CREKA targeting moiety are well-known therapeutic agents, especially in
Externí odkaz:
https://doaj.org/article/20072f91186a426695d8bc4c72c657cf
Autor:
Veronika F.S. Pape, Hajnal A. Kovács, István Szatmári, Imre Ugrai, Bence Szikora, Imre Kacskovics, Zoltán May, Norbert Szoboszlai, Gábor Sirokmány, Miklós Geiszt
Publikováno v:
Redox Biology, Vol 54, Iss , Pp 102385- (2022)
Peroxidasin (PXDN) is involved in the crosslinking of collagen IV, a major constituent of basement membranes. Disruption of basement membrane integrity as observed in genetic alterations of collagen IV or PXDN can result in developmental defects and
Externí odkaz:
https://doaj.org/article/4866fced8ba64f3cbfd41c2056d07b2c
Publikováno v:
Atmosphere, Vol 13, Iss 8, p 1218 (2022)
Official air quality (AQ) stations are sporadically located in cities to monitor the anthropogenic pollutant levels. Consequently, their data cannot be used for further locations to estimate hidden changes in AQ and local emissions. Low-cost sensors
Externí odkaz:
https://doaj.org/article/8b83c4c4018a46309ed82b709d39757c
Autor:
Zoltán Hujber, Gergő Horváth, Gábor Petővári, Ildikó Krencz, Titanilla Dankó, Katalin Mészáros, Hajnalka Rajnai, Norbert Szoboszlai, William P. J. Leenders, András Jeney, László Tretter, Anna Sebestyén
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-12 (2018)
Abstract Background Bioenergetic characterisation of malignant tissues revealed that different tumour cells can catabolise multiple substrates as salvage pathways, in response to metabolic stress. Altered metabolism in gliomas has received a lot of a
Externí odkaz:
https://doaj.org/article/90f0a1f23bba46a683991c7a09783d5b
Autor:
Zoltán Hujber, Gábor Petővári, Norbert Szoboszlai, Titanilla Dankó, Noémi Nagy, Csilla Kriston, Ildikó Krencz, Sándor Paku, Olivér Ozohanics, László Drahos, András Jeney, Anna Sebestyén
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 36, Iss 1, Pp 1-12 (2017)
Abstract Background Multiple studies concluded that oncometabolites (e.g. D-2-hydroxyglutarate (2-HG) related to mutant isocitrate dehydrogenase 1/2 (IDH1/2) and lactate) have tumour promoting potential. Regulatory mechanisms implicated in the mainte
Externí odkaz:
https://doaj.org/article/1c8ed741a22d4def9eb36e58f86bf587
Autor:
Gergely Szakács, Norbert Szoboszlai, Jozsef Tovari, Pál T. Szabó, Christina Streli, Beáta G. Vértessy, György Várady, Nóra Kucsma, Judit E. Szabó, Melinda Gera, Anikó Gaál, Veronika F.S. Pape, Szilárd Tóth, Dóra Türk, Mihály Cserepes
Supplementary tables and figures, supplementary materials and methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e819c0db7a5bd45216d4aaf201c1b0d
https://doi.org/10.1158/0008-5472.22424827
https://doi.org/10.1158/0008-5472.22424827
Autor:
Gergely Szakács, Norbert Szoboszlai, Jozsef Tovari, Pál T. Szabó, Christina Streli, Beáta G. Vértessy, György Várady, Nóra Kucsma, Judit E. Szabó, Melinda Gera, Anikó Gaál, Veronika F.S. Pape, Szilárd Tóth, Dóra Türk, Mihály Cserepes
Clinical evidence shows that following initial response to treatment, drug-resistant cancer cells frequently evolve and, eventually, most tumors become resistant to all available therapies. We compiled a focused library consisting of >500 commerciall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d3bfd0cd96c275f4f36becbac6d1fe4
https://doi.org/10.1158/0008-5472.c.6511876
https://doi.org/10.1158/0008-5472.c.6511876
Autor:
Anikó Gaál, Tamás M. Garay, Ildikó Horváth, Domokos Máthé, Dávid Szöllősi, Dániel S. Veres, Jeremiah Mbuotidem, Tibor Kovács, József Tóvári, Ralf Bergmann, Christina Streli, Gergely Szakács, Judith Mihály, Zoltán Varga, Norbert Szoboszlai
Publikováno v:
Pharmaceutics, Vol 12, Iss 5, p 466 (2020)
Liposomes containing copper and the copper ionophore neocuproine were prepared and characterized for in vitro and in vivo anticancer activity. Thermosensitive PEGylated liposomes were prepared with different molar ratios of 1,2-dipalmitoyl-sn-glycero
Externí odkaz:
https://doaj.org/article/9b41118e9fb848bf881c307bc2b2ce49
Autor:
Jelena Poljarević, Istvan Szatmari, János P. Mészáros, Norbert Szoboszlai, Éva A. Enyedy, Gabriella Spengler, Oszkár Csuvik, Ferenc Fülöp
Publikováno v:
Dalton Transactions
Herein the design and synthesis of a new 8-hydroxyquinoline derivative, (S)-5-chloro-7-((proline-1-yl)methyl)8-hydroxyquinoline (HQCl-Pro), with good water solubility and multidrug resistance reversal activity are reported. In this work the proton di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee6e50c473ed3733cde0568c057c1f6e
https://doi.org/10.1039/d0dt01256d
https://doi.org/10.1039/d0dt01256d
Autor:
Gergely Szakács, Norbert Szoboszlai, Veronika F.S. Pape, István Szatmári, Éva A. Enyedy, Christina Streli, Nóra Kucsma, Ferenc Fülöp, Anikó Gaál
Publikováno v:
Cancers, Vol 13, Iss 154, p 154 (2021)
Cancers
Volume 13
Issue 1
Cancers
Volume 13
Issue 1
Resistance to chemotherapeutic agents is a major obstacle in cancer treatment. A recently proposed strategy is to target the collateral sensitivity of multidrug resistant (MDR) cancer. Paradoxically, the toxicity of certain metal chelating agents is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b7095bd089798e4d40138415cc02af8
https://pubmed.ncbi.nlm.nih.gov/33466433
https://pubmed.ncbi.nlm.nih.gov/33466433