Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Norbert, Lange"'
Autor:
Manish Jain, Jordan Bouilloux, Ines Borrego, Stéphane Cook, Hubert van den Bergh, Norbert Lange, Georges Wagnieres, Marie-Noelle Giraud
Publikováno v:
Pharmaceuticals, Vol 15, Iss 5, p 564 (2022)
Cathepsin B is a lysosomal cysteine protease that plays an important role in cancer, atherosclerosis, and other inflammatory diseases. The suppression of cathepsin B can inhibit tumor growth. The overexpression of cathepsin B can be used for the imag
Externí odkaz:
https://doaj.org/article/6d2d7d0df4824020924de0f3895f4f53
5-Aminolevulinic Acid-Squalene Nanoassemblies for Tumor Photodetection and Therapy: In Vitro Studies
Publikováno v:
Nanoscale Research Letters, Vol 13, Iss 1, Pp 1-9 (2018)
Abstract Protoporphyrin IX (PpIX) as natural photosensitizer derived from administration of 5-aminolevulinic acid (5-ALA) has found clinical use for photodiagnosis and photodynamic therapy of several cancers. However, broader use of 5-ALA in oncology
Externí odkaz:
https://doaj.org/article/838dea3835cd492a8317ce67467ff9af
Publikováno v:
Molecules, Vol 26, Iss 20, p 6241 (2021)
Cyclopeptidic photosensitizer prodrugs (cPPPs) are compounds designed to specifically target overexpressed hydrolases such as serine proteases, resulting in their specific activation in close proximity to tumor cells. In this study, we explored a ser
Externí odkaz:
https://doaj.org/article/9560c0594ce44d5d972a02359784c3f1
PDF file - 300KB, Bioluminescence imaging of three PCa-xenografted-mice before and 30 days after PDT. Animals bearing subcutaneous prostate tumors were treated with 7.5 mg/kg of uPA-PPP as Pba equivalents and 16 hours after injection, tumors were irr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e441de909da2c585b85e56c6c625235
https://doi.org/10.1158/1535-7163.22498555.v1
https://doi.org/10.1158/1535-7163.22498555.v1
Publikováno v:
Molecules, Vol 25, Iss 18, p 4285 (2020)
Cyclopeptidic chemotherapeutic prodrugs (cPCPs) are macromolecular protease-sensitive doxorubicin (DOX) prodrugs synthesized from a cyclodecapeptidic scaffold, termed Regioselectively Addressable Functionalized Template (RAFT). In order to increase t
Externí odkaz:
https://doaj.org/article/c0c063228ac94ad582621383e590b86a
Autor:
Martin Kiening, Norbert Lange
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 23; Pages: 14900
Today, most research on treating cancers targets one single cancer, often because of the very specific operation principle of the therapy. For instance, immunotherapies require the expression of a particular antigen, which might not be expressed in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b57834be8c6921bd044c22bb0405f462
Autor:
Martin Kiening, Norbert Lange
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 244:112717
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5ec9716d24b9f3bf76c7ac88aa25d9b
https://doi.org/10.1016/j.jphotobiol.2023.112717
https://doi.org/10.1016/j.jphotobiol.2023.112717
Publikováno v:
Pharmaceuticals, Vol 12, Iss 4, p 148 (2019)
Photodynamic therapy (PDT) and photodiagnosis (PD) are essential approaches in the field of biophotonics. Ideally, both modalities require the selective sensitization of the targeted disease in order to avoid undesired phenomena such as the destructi
Externí odkaz:
https://doaj.org/article/bd37dce4dda8476184579be94d913a0b
Autor:
Francesca Bryden, Margarita Mora, Ross W. Boyle, Norbert Lange, M. Lluïsa Sagristá, Ester Boix-Garriga, Montserrat Agut, Santi Nonell, Elena de las Heras
Publikováno v:
Photochemistry and Photobiology. 96:570-580
Active targeting strategies are currently being extensively investigated in order to enhance the selectivity of photodynamic therapy. The aim of the present research was to evaluate whether the external decoration of nanopolymeric carriers with targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f583ff1d6eab632e01faab8784c3c9ef
https://doi.org/10.1111/php.13238
https://doi.org/10.1111/php.13238