Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Norazizah Shafee"'
Autor:
Shailendra Kumar Verma, Fernanda Ana-Sosa-Batiz, Julia Timis, Norazizah Shafee, Erin Maule, Paolla Beatriz Almeida Pinto, Chris Conner, Kristen M. Valentine, Dale O. Cowley, Robyn Miller, Annie Elong Ngono, Linda Tran, Krithik Varghese, Rúbens Prince Dos Santos Alves, Kathryn M. Hastie, Erica Ollmann Saphire, David R. Webb, Kurt Jarnagin, Kenneth Kim, Sujan Shresta
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105361- (2024)
Summary: Background: Mouse models that recapitulate key features of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection are important tools for understanding complex interactions between host genetics, immune responses, and SARS-Co
Externí odkaz:
https://doaj.org/article/04220e5ef32e4419879fefba16782ce9
Autor:
Rúbens Prince dos Santos Alves, Julia Timis, Robyn Miller, Kristen Valentine, Paolla Beatriz Almeida Pinto, Andrew Gonzalez, Jose Angel Regla-Nava, Erin Maule, Michael N. Nguyen, Norazizah Shafee, Sara Landeras-Bueno, Eduardo Olmedillas, Brett Laffey, Katarzyna Dobaczewska, Zbigniew Mikulski, Sara McArdle, Sarah R. Leist, Kenneth Kim, Ralph S. Baric, Erica Ollmann Saphire, Annie Elong Ngono, Sujan Shresta
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract SARS-CoV-2-reactive T cells are detected in some healthy unexposed individuals. Human studies indicate these T cells could be elicited by the common cold coronavirus OC43. To directly test this assumption and define the role of OC43-elicited
Externí odkaz:
https://doaj.org/article/9ae5cf7c26864a23845ea55a62b14b62
Autor:
Emilie Branche, Ying-Ting Wang, Karla M. Viramontes, Joan M. Valls Cuevas, Jialei Xie, Fernanda Ana-Sosa-Batiz, Norazizah Shafee, Sascha H. Duttke, Rachel E. McMillan, Alex E. Clark, Michael N. Nguyen, Aaron F. Garretson, Jan J. Crames, Nathan J. Spann, Zhe Zhu, Jeremy N. Rich, Deborah H. Spector, Christopher Benner, Sujan Shresta, Aaron F. Carlin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Zika virus (ZIKV) infection suppresses the induction of dendritic cell (DC)-derived immunity, but the underlying mechanistical insights are still lacking. Here the authors show, using in vitro systems profiling of DC transcriptome and epigenome, that
Externí odkaz:
https://doaj.org/article/8fc6f2849f18424eb3cf7370ce4d7945
Autor:
Suhaili Mustafa, Noraini Abd-Aziz, Wuan-Ting Saw, Sien-Yei Liew, Khatijah Yusoff, Norazizah Shafee
Publikováno v:
Vaccines, Vol 8, Iss 4, p 742 (2020)
Enterovirus 71 (EV71) is the major causative agent in hand, foot, and mouth disease (HFMD), and it mainly infects children worldwide. Despite the risk, there is no effective vaccine available for this disease. Hence, a recombinant protein construct o
Externí odkaz:
https://doaj.org/article/df59efafbea94ae291624dd480cc780e
Publikováno v:
International Journal of Molecular Sciences, Vol 13, Iss 2, Pp 1582-1597 (2012)
Vanda Mimi Palmer (VMP), an orchid hybrid of Vanda tesselata and Vanda Tan Chay Yan is a highly scented tropical orchid which blooms all year round. Previous studies revealed that VMP produces a variety of isoprenoid volatiles during daylight. Isopre
Externí odkaz:
https://doaj.org/article/f9633a9d06ec4399b925ca57ef35ea3c
Autor:
Adelene Ai-Lian Song, Janna Ong Abdullah, Mohd Puad Abdullah, Norazizah Shafee, Roohaida Othman, Ee-Fun Tan, Normah Mohd Noor, Abdul Rahim Raha
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52444 (2012)
Isoprenoids are a large and diverse group of metabolites with interesting properties such as flavour, fragrance and therapeutic properties. They are produced via two pathways, the mevalonate pathway or the 2-C-methyl-D-erythritol-4-phosphate (MEP) pa
Externí odkaz:
https://doaj.org/article/6d3fd3adf7e24d80ab3eead11b36df8b
Autor:
Eva Y-H. P. Lee, Eric J. Stanbridge, Gabriel N. Hortobagyi, Gordon B. Mills, Yoon Kim, Shuanzeng Wei, Christopher R. Smith, Norazizah Shafee
The majority of BRCA1-associated breast cancers are basal cell–like, which is associated with a poor outcome. Using a spontaneous mouse mammary tumor model, we show that platinum compounds, which generate DNA breaks during the repair process, are m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e52333118eaf66fe7870ed8b8d96c6e
https://doi.org/10.1158/0008-5472.c.6497703
https://doi.org/10.1158/0008-5472.c.6497703
Activation of the mitogen-activated protein kinase (MAPK) pathway plays a major role in neoplastic cell transformation. Using a proteomics approach, we identified α tubulin and β tubulin as proteins that interact with activated MAP/extracellular si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::573229dab24b2600c18970fcf6f2830a
https://doi.org/10.1158/0008-5472.c.6500679.v1
https://doi.org/10.1158/0008-5472.c.6500679.v1
Supplementary Figures 1-3 from Mitogen-Activated Protein/Extracellular Signal-Regulated Kinase Kinase 1act/Tubulin Interaction Is an Important Determinant of Mitotic Stability in Cultured HT1080 Human Fibrosarcoma Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::749bfc4b9e525f28670f35446d94b8c2
https://doi.org/10.1158/0008-5472.22383852.v1
https://doi.org/10.1158/0008-5472.22383852.v1
Supplementary Figure Legends 1-3 from Mitogen-Activated Protein/Extracellular Signal-Regulated Kinase Kinase 1act/Tubulin Interaction Is an Important Determinant of Mitotic Stability in Cultured HT1080 Human Fibrosarcoma Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b212da1c5700ee755a7e14504b2234a
https://doi.org/10.1158/0008-5472.22383855
https://doi.org/10.1158/0008-5472.22383855