Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Noraylis Lorenzo"'
Publikováno v:
Biotecnología Aplicada, Vol 29, Iss 3, Pp 146-154
Rheumatoid arthritis is a degenerative disease characterized by chronic inflammation of peripheral joints. The first line of treatment involves the use of potent anti-inflammatory and immunosuppressive drugs, leading to an overall suppression of the
Externí odkaz:
https://doaj.org/article/e65915168637495f8c02fc8d751f3b38
Autor:
Ania Cabrales-Rico, Luis Javier González, Yassel Ramos, Yusimi Reyes, Hilda Garay, Osmel García, Yordanka Masforrol, Ana Marta López, Vladimir Besada, María Domínguez, Noraylis Lorenzo, Jorge Alexis, Dinhora Prada
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 143
CIGB-814, originally named as E18-3 APL1 or APL1 in preclinical experiments, is a novel therapeutic peptide candidate for Rheumatoid Arthritis (RA). It is an altered peptide ligand containing a novel CD4+ T-cell epitope of human heat shock protein 60
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6cecb38e35a4ed20524c02d3def54e0
https://pubmed.ncbi.nlm.nih.gov/28595106
https://pubmed.ncbi.nlm.nih.gov/28595106
Autor:
Noraylis Lorenzo, F Altruda, O Reyes, J Ancizar, Isabel M. Hernandez, Rafael Gil, Gabriel Padrón, Ana María Torres, Maria Victoria Hernández, Ariana Barberá, L Silengo, Maria del Carmen Dominguez, H Garay
Publikováno v:
Autoimmunity. 45:449-459
Rheumatoid arthritis is a systemic autoimmune disease mediated by T cells. Productive engagement of T cell receptors by major histocompatibility complex-peptide leads to proliferation, differentiation and the definition of effector functions. Altered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::661c4aec6a7448fe1308f2e72305624f
https://doi.org/10.3109/08916934.2012.697592
https://doi.org/10.3109/08916934.2012.697592
Autor:
Guillaume Darrasse-Jèze, David Klatzmann, Rafael Gil, Maria Victoria Hernández, Ariana Barberá, Maria del Carmen Dominguez, Isabel M. Hernandez, Gabriel Padrón, Noraylis Lorenzo, Ana María Torres
Publikováno v:
Autoimmunity. 44(6)
Induction of immune tolerance as therapeutic approach for autoimmune diseases constitutes a current research focal point. In this sense, we aimed to evaluate an altered peptide ligand (APL) for induction of peripheral tolerance in patients with rheum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5e9bfce59b5197ce8df8e1c52e2f02e
https://pubmed.ncbi.nlm.nih.gov/21370936
https://pubmed.ncbi.nlm.nih.gov/21370936
Publikováno v:
Biotecnología Aplicada, Vol 29, Iss 3, Pp 146-154
Rheumatoid arthritis is a degenerative disease characterized by chronic inflammation of peripheral joints. The first line of treatment involves the use of potent anti-inflammatory and immunosuppressive drugs, leading to an overall suppression of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::4599f335d76a0692d06cb08947ebbd38
http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1027-28522012000300001&lng=en&tlng=en
http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1027-28522012000300001&lng=en&tlng=en
Autor:
Ariana Barberá, Ramón G Padrón, Yamile Heredia, María Domínguez, Elsy Chall, Lourdes Franco, Noraylis Lorenzo, Dolores Cantera, Amarys Alonso
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 9, Iss Suppl 1, p P182 (2011)
Pediatric Rheumatology Online Journal
Pediatric Rheumatology Online Journal
Methods First, a novel T cell epitope from human heat-shock protein 60 (Hsp60), an autoantigen involved in the pathogenesis of JIA and other autoimmune diseases, was identified by bioinformatics tools and an APL was design starting from this epitope.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35830a6870c6339933073bfe813e7d9c