Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Nora Yucel"'
Autor:
Adelaida R. Palla, Keren I. Hilgendorf, Ann V. Yang, Jaclyn P. Kerr, Aaron C. Hinken, Janos Demeter, Peggy Kraft, Nancie A. Mooney, Nora Yucel, David M. Burns, Yu Xin Wang, Peter K. Jackson, Helen M. Blau
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Repair of muscle damage requires muscle stem cells, which lose regenerative capacity with aging. Here, the authors show that a sensory organelle, the primary cilium, is critical for muscle stem cell proliferation during regeneration and lost with agi
Externí odkaz:
https://doaj.org/article/1cb547b9df374953936e2d5fd08f29bc
Autor:
Roman Tsaryk, Nora Yucel, Elvin V. Leonard, Noelia Diaz, Olga Bondareva, Maria Odenthal-Schnittler, Zoltan Arany, Juan M. Vaquerizas, Hans Schnittler, Arndt F. Siekmann
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Endothelial cells (ECs) lining blood vessels are exposed to mechanical forces, such as shear stress. These forces control many aspects of EC biology, including vascular tone, cell migration and proliferation. Despite a good understanding of
Externí odkaz:
https://doaj.org/article/e9ca20b3579e44998fd8e2a75ff11d71
Cardiac endothelial cells maintain open chromatin and expression of cardiomyocyte myofibrillar genes
Publikováno v:
eLife, Vol 9 (2020)
Endothelial cells (ECs) are widely heterogenous depending on tissue and vascular localization. Jambusaria et al. recently demonstrated that ECs in various tissues surprisingly possess mRNA signatures of their underlying parenchyma. The mechanism unde
Externí odkaz:
https://doaj.org/article/300a5d84f9b145109265903671a3758c
Autor:
Jonathan J. Edwards, Jeffrey Brandimarto, Dong-Qing Hu, Sunhye Jeong, Nora Yucel, Li Li, Kenneth C. Bedi, Shogo Wada, Danielle Murashige, Hyun Tae V. Hwang, Mingming Zhao, Kenneth B. Margulies, Daniel Bernstein, Sushma Reddy, Zoltan Arany
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2020)
Background: No medical therapies exist to treat right ventricular (RV) remodeling and RV failure (RVF), in large part because molecular pathways that are specifically activated in pathologic human RV remodeling remain poorly defined. Murine models ha
Externí odkaz:
https://doaj.org/article/73b70bc22b134e9492def4bd02201ff2
Autor:
Nora Yucel, Yu Xin Wang, Thach Mai, Ermelinda Porpiglia, Peder J. Lund, Glenn Markov, Benjamin A. Garcia, Sean C. Bendall, Michael Angelo, Helen M. Blau
Publikováno v:
Cell Reports, Vol 27, Iss 13, Pp 3939-3955.e6 (2019)
Summary: The impact of glucose metabolism on muscle regeneration remains unresolved. We identify glucose metabolism as a crucial driver of histone acetylation and myogenic cell fate. We use single-cell mass cytometry (CyTOF) and flow cytometry to cha
Externí odkaz:
https://doaj.org/article/a6a7fe8b0fb044af811f41a7b1931889
Publikováno v:
npj Regenerative Medicine, Vol 5, Iss 1, Pp 1-1 (2020)
A correction to this paper has been published: https://doi.org/10.1038/s41536-020-00112-0.
Externí odkaz:
https://doaj.org/article/cfd16b4fe1aa4a4d862608d0957e08c7
Publikováno v:
eLife, Vol 4 (2015)
The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of 50 papers in the field of cancer biology published between 2010 and 2012. This Registered report
Externí odkaz:
https://doaj.org/article/9d1f369bad67485296ef4de692cc7395
Autor:
Nora Yucel, Silvia Marchiano, Evan Tchelepi, Germana Paterlini, Quentin McAfee, Nehaar Nimmagadda, Andy Ren, Sam Shi, Charles Murry, Zoltan Arany
How SARS-CoV-2 causes the observed range of clinical manifestations and disease severity remains poorly understood. SARS-CoV-2 encodes for two proteases (3CLPro and PLPro), vital for viral production, but also promiscuous with respect to host protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4804c0a588d842925f4de2e59203b14
https://doi.org/10.1101/2022.01.17.476677
https://doi.org/10.1101/2022.01.17.476677
Autor:
Nora Yucel, Zolt Arany
Publikováno v:
Curr Opin Physiol
Endothelial cells line all blood vessels in vertebrates. These cells contribute to whole-body nutrient distribution in a variety of ways, including regulation of local blood flow, regulation of trans-endothelial nutrient transport, and paracrine effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40deff4e220348fd4df7fac3159d7754
https://doi.org/10.1016/j.cophys.2019.09.003
https://doi.org/10.1016/j.cophys.2019.09.003