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pro vyhledávání: '"Nora S. Siefert"'
Autor:
Edoardo Ratto, S. Roy Chowdhury, Nora S. Siefert, Martin Schneider, Marten Wittmann, Dominic Helm, Wilhelm Palm
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
mTORC1 blocks lysosomal nutrient generation. Here, the authors show that mTORC1 inactivation triggers V-ATPase assembly, which rapidly initiates lysosomal acidification and degradation of protein contents throughout the lysosomal population.
Externí odkaz:
https://doaj.org/article/8559f72c4bbd46828666b8488f786076