Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Nora P Goette"'
Autor:
Geraldine De Luca, Nora P. Goette, Paola R. Lev, Maria C. Baroni Pietto, Cecilia P. Marin Oyarzún, Miguel A. Castro Ríos, Beatriz Moiraghi, Federico Sackmann, Laureano J. Kamiya, Veronica Verri, Victoria Caula, Vanina Fernandez, Angeles Vicente, Julio Pose Cabarcos, Vanesa Caruso, Maria F. Camacho, Irene B. Larripa, Marina Khoury, Rosana F. Marta, Ana C. Glembotsky, Paula G. Heller
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Inflammation plays a pivotal role in the pathogenesis of primary and post-essential thrombocythemia or post-polycythemia vera myelofibrosis (MF) in close cooperation with the underlying molecular drivers. This inflammatory state is induced by a dynam
Externí odkaz:
https://doaj.org/article/5df717c398dd4954b8dd7bab8a1b84c2
Autor:
Nora P Goette, Ana C Glembotsky, Paola R Lev, Matías Grodzielski, Geraldine Contrufo, Marta S Pierdominici, Yesica R Espasandin, Dardo Riveros, Alejandro J García, Felisa C Molinas, Paula G Heller, Rosana F Marta
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160563 (2016)
Mechanisms leading to decreased platelet count in immune thrombocytopenia (ITP) are heterogeneous. This study describes increased platelet apoptosis involving loss of mitochondrial membrane potential (ΔΨm), caspase 3 activation (aCasp3) and phospha
Externí odkaz:
https://doaj.org/article/bc764d30bd6a4f0e9a65c2e73f793414
Autor:
Geraldine De Luca, Paola R. Lev, Maria F. Camacho, Nora P. Goette, Federico Sackmann, Miguel A. Castro Ríos, Beatriz Moiraghi, Veronica Cortes Guerrieri, Georgina Bendek, Emiliano Carricondo, Alicia Enrico, Veronica Vallejo, Ana Varela, Marina Khoury, Marina Gutierrez, Irene B. Larripa, Rosana F. Marta, Ana C. Glembotsky, Paula G. Heller
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Myelofibrosis (MF) is a clonal hematopoietic stem cell disorder classified among chronic myeloproliferative neoplasms, characterized by exacerbated myeloid and megakaryocytic proliferation and bone marrow fibrosis. It is induced by driver (JAK2/CALR/
Externí odkaz:
https://doaj.org/article/5d6f229ff02c42ab976c494419308bc5
Pathogenic mechanisms contributing to thrombocytopenia in patients with systemic lupus erythematosus
Autor:
M. Constanza Baroni Pietto, Paola R. Lev, Ana C. Glembotsky, Cecilia P. Marín Oyarzún, Graciela Gomez, Victoria Collado, Cecilia Pisoni, Ramiro A. Gomez, Matías Grodzielski, Jacqueline Gonzalez, Karina V. Mariño, Paula G. Heller, Nora P. Goette, Rosana F. Marta
Publikováno v:
Platelets, Vol 33, Iss 5, Pp 743-754 (2022)
Systemic lupus erythematosus (SLE) is an autoimmune condition developing thrombocytopenia in about 10–15% of cases, however, mechanisms leading to low platelet count were not deeply investigated in this illness. Here we studied possible causes of t
Externí odkaz:
https://doaj.org/article/6b513b6ff98045f69f1dba0a75e76380
Autor:
María Lucía Rosenberg, Agustín Yaneff, Gonzalo Manuel Ferradás, Margarita Paz Villafañe Tapia, Carlos Alberto Davio, Nora Paula Goette, Sandra Gabriela Vlachovsky, Roxana Noemí Peroni, Elisabet Mónica Oddo, Pablo Javier Azurmendi
Publikováno v:
Life, Vol 13, Iss 9, p 1817 (2023)
ADPKD is the most common genetic renal disease, characterized by the presence of multiple cysts which, through slow and gradual growth, lead to glomerular filtration rate (GFR) decline and end-stage renal disease. Cystic growth is associated with inc
Externí odkaz:
https://doaj.org/article/3a1efb60e3844e4ba46c078f80b4eab6
Autor:
Ana C. Glembotsky, Cecilia P. Marin Oyarzún, Geraldine De Luca, Christophe Marzac, Nathalie Auger, Nora P. Goette, Rosana F. Marta, Hana Raslova, Paula G. Heller
Publikováno v:
Haematologica, Vol 105, Iss 10 (2020)
Externí odkaz:
https://doaj.org/article/a61daa6f8d7444bebdd2a4aca751d131
Autor:
Cecilia P. Marín Oyarzún, Ana C. Glembotsky, Nora P. Goette, Paola R. Lev, Geraldine De Luca, María C. Baroni Pietto, Beatriz Moiraghi, Miguel A. Castro Ríos, Angeles Vicente, Rosana F. Marta, Mirta Schattner, Paula G. Heller
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Essential thrombocythemia (ET) is comprised among chronic myeloproliferative neoplasms (MPN) and is caused by driver mutations in JAK2, CALR, and MPL, which lead to megakaryocyte proliferation and prominent thrombocytosis. Thrombosis remains the main
Externí odkaz:
https://doaj.org/article/c645814c0eff4aa58503e674a2eb6b47
Autor:
Juan P. Salim, Ana C. Glembotsky, Paola R. Lev, Cecilia P. Marin Oyarzún, Nora P. Goette, Felisa C. Molinas, Rosana F. Marta, Paula G. Heller
Publikováno v:
Platelets, Vol 28, Iss 6, Pp 602-606 (2017)
The SDF-1-CXCR4 axis plays an essential role in the regulation of platelet production, by directing megakaryocyte (MK) migration toward the vascular niche, thus allowing terminal maturation and proplatelet formation, and also regulates platelet funct
Externí odkaz:
https://doaj.org/article/9930007e5cf5435d86432ae6f12f066b
Autor:
Ana C. Glembotsky, Dominika Sliwa, Dominique Bluteau, Nathalie Balayn, Cecilia P. Marin Oyarzún, Anna Raimbault, Marie Bordas, Nathalie Droin, Iryna Pirozhkova, Valance Washington, Nora P. Goette, Rosana F. Marta, Rémi Favier, Hana Raslova, Paula G. Heller
Publikováno v:
Haematologica, Vol 104, Iss 6 (2019)
Germline RUNX1 mutations lead to thrombocytopenia and platelet dysfunction in familial platelet disorder with predisposition to acute myelogenous leukemia (AML). Multiple aspects of platelet function are impaired in these patients, associated with al
Externí odkaz:
https://doaj.org/article/339e7f5175834da7a016b084f1a82957
Autor:
Nora P. Goette, Francisco R. Borzone, Ailen D. Discianni Lupi, Norma A. Chasseing, María F. Rubio, Mónica A. Costas, Paula G. Heller, Rosana F. Marta, Paola R. Lev
Publikováno v:
Experimental hematology. 107
Bone marrow stromal cells provide a proper environment for the development of hematologic lineages. The incorporation of different stromal cells into in vitro culture systems would be an attractive model to study megakaryopoiesis and thrombopoiesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0363851127914b63780487307ff20a09
https://pubmed.ncbi.nlm.nih.gov/35032592
https://pubmed.ncbi.nlm.nih.gov/35032592