Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Nora Pällmann"'
Autor:
Yang Jin, Ling Wang, Su Qu, Xia Sheng, Alexandr Kristian, Gunhild M Mælandsmo, Nora Pällmann, Erkan Yuca, Ibrahim Tekedereli, Kivanc Gorgulu, Neslihan Alpay, Anil Sood, Gabriel Lopez‐Berestein, Ladan Fazli, Paul Rennie, Bjørn Risberg, Håkon Wæhre, Håvard E Danielsen, Bulent Ozpolat, Fahri Saatcioglu
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 3, Pp 315-331 (2015)
Abstract The six transmembrane protein of prostate 2 (STAMP2) is an androgen‐regulated gene whose mRNA expression is increased in prostate cancer (PCa). Here, we show that STAMP2 protein expression is increased in human PCa compared with benign pro
Externí odkaz:
https://doaj.org/article/4aeac316ce514471a35047b46240bd93
Autor:
Henning Sievert, Nora Pällmann, Katharine K. Miller, Irm Hermans-Borgmeyer, Simone Venz, Ataman Sendoel, Michael Preukschas, Michaela Schweizer, Steffen Boettcher, P. Christoph Janiesch, Thomas Streichert, Reinhard Walther, Michael O. Hengartner, Markus G. Manz, Tim H. Brümmendorf, Carsten Bokemeyer, Melanie Braig, Joachim Hauber, Kent E. Duncan, Stefan Balabanov
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 8, Pp 963-976 (2014)
The central importance of translational control by post-translational modification has spurred major interest in regulatory pathways that control translation. One such pathway uniquely adds hypusine to eukaryotic initiation factor 5A (eIF5A), and the
Externí odkaz:
https://doaj.org/article/1c3ec82d54394b81a23dc5254fab1567
Autor:
Michael Preukschas, Christian Hagel, Alexander Schulte, Kristoffer Weber, Katrin Lamszus, Henning Sievert, Nora Pällmann, Carsten Bokemeyer, Joachim Hauber, Melanie Braig, Stefan Balabanov
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43468 (2012)
Glioblastomas are highly aggressive brain tumors of adults with poor clinical outcome. Despite a broad range of new and more specific treatment strategies, therapy of glioblastomas remains challenging and tumors relapse in all cases. Recent work demo
Externí odkaz:
https://doaj.org/article/be8aa09ce7fd49a9bb62600e7a6decc7
Autor:
Fahri Saatcioglu, Omer F. Kuzu, Yang Jin, Aykut Üren, Partha P. Banerjee, Paul S. Rennie, Ladan Fazli, Havard Emil Danielsen, Wanja Kildal, Bulent Ozpolat, Hamada M. Mokhlis, Nermin Kahraman, Nicolai Sebastian Frengen, Yixin Jin, Martina Tesikova, Marte Livgård, Ke Deng, Nora Pällmann
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c174cb4daf5df1c4d486d6df399723a
https://doi.org/10.1158/0008-5472.22428829.v1
https://doi.org/10.1158/0008-5472.22428829.v1
Autor:
Fahri Saatcioglu, Omer F. Kuzu, Yang Jin, Aykut Üren, Partha P. Banerjee, Paul S. Rennie, Ladan Fazli, Havard Emil Danielsen, Wanja Kildal, Bulent Ozpolat, Hamada M. Mokhlis, Nermin Kahraman, Nicolai Sebastian Frengen, Yixin Jin, Martina Tesikova, Marte Livgård, Ke Deng, Nora Pällmann
One-carbon (1C) metabolism has a key role in metabolic programming with both mitochondrial (m1C) and cytoplasmic (c1C) components. Here we show that activating transcription factor 4 (ATF4) exclusively activates gene expression involved in m1C, but n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccae10abe0c2bbcfb20accc79852acb9
https://doi.org/10.1158/0008-5472.c.6513160.v1
https://doi.org/10.1158/0008-5472.c.6513160.v1
Autor:
Marte Livgård, Bulent Ozpolat, Nora Pällmann, Partha P. Banerjee, Nicolai Sebastian Frengen, Martina Tesikova, Omer F. Kuzu, Håvard E. Danielsen, Yixin Jin, Ke Deng, Paul S. Rennie, Hamada M. Mokhlis, Nermin Kahraman, Wanja Kildal, Yang Jin, Aykut Üren, Ladan Fazli, Fahri Saatcioglu
Publikováno v:
Cancer Research
One-carbon (1C) metabolism has a key role in metabolic programming with both mitochondrial (m1C) and cytoplasmic (c1C) components. Here we show that activating transcription factor 4 (ATF4) exclusively activates gene expression involved in m1C, but n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b5d24adf3441ae5521238c32736f85d
https://hdl.handle.net/11250/3064234
https://hdl.handle.net/11250/3064234
Autor:
Erman Akkus, Partha P. Banerjee, Nora Pällmann, Jørgen Sikkeland, Yang Jin, Paul S. Rennie, Nermin Kahraman, Bulent Ozpolat, Hatice Zeynep Nenseth, Martina Tesikova, Manohar Pradhan, Håvard E. Danielsen, Ladan Fazli, Marte Livgård, Yixin Jin, Fahri Saatcioglu, Dogukan Koc, Hamada M. Mokhlis, Aykut Üren, Omer F. Kuzu
Cancer cells exploit many of the cellular adaptive responses to support their survival needs. One such critical pathway in eukaryotic cells is the unfolded protein response (UPR) that is important in normal physiology as well as disease states, inclu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97aab882cea825d6dc4014a2b7db5955
http://hdl.handle.net/10852/76055
http://hdl.handle.net/10852/76055
Autor:
Melanie Neumann, Henning Sievert, Claus-Henning Nagel, Michael Preukschas, Michaela Schweizer, Stefan Balabanov, Christian Hagel, Eugenia Haralambieva, Irm Hermans-Borgmeyer, Carsten Bokemeyer, Nora Pällmann, Peter J. Wild, Melanie Braig, Joachim Hauber
Publikováno v:
Journal of Biological Chemistry. 290:18343-18360
Hypusine modification of the eukaryotic initiation factor 5A (eIF-5A) is emerging as a crucial regulator in cancer, infections, and inflammation. Although its contribution in translational regulation of proline repeat-rich proteins has been sufficien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fda458582d82310426d2e405348c78e
https://doi.org/10.1074/jbc.m115.664490
https://doi.org/10.1074/jbc.m115.664490
Autor:
Irm Hermans-Borgmeyer, P. Christoph Janiesch, Nora Pällmann, Kent E. Duncan, Henning Sievert, Simone Venz, Michael O. Hengartner, Stefan Balabanov, Thomas Streichert, Tim H. Brümmendorf, Markus G. Manz, Michaela Schweizer, Katharine K. Miller, Reinhard Walther, Ataman Sendoel, Michael Preukschas, Melanie Braig, Joachim Hauber, Steffen Boettcher, Carsten Bokemeyer
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 8, Pp 963-976 (2014)
Disease Models & Mechanisms
Disease models & mechanisms
Disease Models & Mechanisms
Disease models & mechanisms
The central importance of translational control by posttranslational modification has spurred major interest in regulatory pathways that control translation. One such pathway uniquely adds hypusine to eukaryotic initiation factor 5A (eIF5A), and ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b5058b5cf4bca8c9728e10b24e44eb9
http://dmm.biologists.org/content/7/8/963
http://dmm.biologists.org/content/7/8/963
Autor:
Reinhard Walther, Kent E. Duncan, Joachim Hauber, Martin Schaletzky, Ralf Pörtner, Oscar Platas-Barradas, Stefan Balabanov, Melanie Braig, Claus-Henning Nagel, Carsten Bokemeyer, Vishnu M. Dhople, Simone Venz, Nora Pällmann, Henning Sievert, Tim H. Brümmendorf, Michael Preukschas
Publikováno v:
Molecular & cellular proteomics : MCP 11 (11): 1289-1305 (2012)
Molecular & Cellular Proteomics : MCP
Molecular & Cellular Proteomics : MCP
Hypusine modification of eukaryotic initiation factor 5A (eIF-5A) represents a unique and highly specific post-translational modification with regulatory functions in cancer, diabetes, and infectious diseases. However, the specific cellular pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57ae31ebc0a28b58a5fe895f18192889
https://doi.org/10.1074/mcp.m112.019059
https://doi.org/10.1074/mcp.m112.019059