Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nora Pällman"'
Autor:
Yang Jin, Ling Wang, Su Qu, Xia Sheng, Alexandr Kristian, Gunhild M Mælandsmo, Nora Pällmann, Erkan Yuca, Ibrahim Tekedereli, Kivanc Gorgulu, Neslihan Alpay, Anil Sood, Gabriel Lopez‐Berestein, Ladan Fazli, Paul Rennie, Bjørn Risberg, Håkon Wæhre, Håvard E Danielsen, Bulent Ozpolat, Fahri Saatcioglu
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 3, Pp 315-331 (2015)
Abstract The six transmembrane protein of prostate 2 (STAMP2) is an androgen‐regulated gene whose mRNA expression is increased in prostate cancer (PCa). Here, we show that STAMP2 protein expression is increased in human PCa compared with benign pro
Externí odkaz:
https://doaj.org/article/4aeac316ce514471a35047b46240bd93
Autor:
Henning Sievert, Nora Pällmann, Katharine K. Miller, Irm Hermans-Borgmeyer, Simone Venz, Ataman Sendoel, Michael Preukschas, Michaela Schweizer, Steffen Boettcher, P. Christoph Janiesch, Thomas Streichert, Reinhard Walther, Michael O. Hengartner, Markus G. Manz, Tim H. Brümmendorf, Carsten Bokemeyer, Melanie Braig, Joachim Hauber, Kent E. Duncan, Stefan Balabanov
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 8, Pp 963-976 (2014)
The central importance of translational control by post-translational modification has spurred major interest in regulatory pathways that control translation. One such pathway uniquely adds hypusine to eukaryotic initiation factor 5A (eIF5A), and the
Externí odkaz:
https://doaj.org/article/1c3ec82d54394b81a23dc5254fab1567
Autor:
Michael Preukschas, Christian Hagel, Alexander Schulte, Kristoffer Weber, Katrin Lamszus, Henning Sievert, Nora Pällmann, Carsten Bokemeyer, Joachim Hauber, Melanie Braig, Stefan Balabanov
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43468 (2012)
Glioblastomas are highly aggressive brain tumors of adults with poor clinical outcome. Despite a broad range of new and more specific treatment strategies, therapy of glioblastomas remains challenging and tumors relapse in all cases. Recent work demo
Externí odkaz:
https://doaj.org/article/be8aa09ce7fd49a9bb62600e7a6decc7
Autor:
David E. Sanin, Ramon I. Klein Geltink, Jing Qiu, George Caputa, Katarzyna M. Grzes, David O’Sullivan, Alanna M. Cameron, Yaarub Musa, Jonathan D. Curtis, Stefanie Scherer, Mauro Corrado, Francesca Alfei, Beth Kelly, Mai Matsushita, Matteo Villa, Nora Pällman, Michael D. Buck, Agnieszka M. Kabat, Edward J. Pearce, Annette E. Patterson, Francesc Baixauli, Joerg M. Buescher, Gerhard Mittler, S. Kyle Austin, Dietmar Zehn, Katelyn Paz, Erika L. Pearce, Ryan Kyle, Cameron S. Field, Sabine Rospert, Lea J. Flachsmann, Ying Zhang, Daniel J. Puleston, Maria Elena Maccari, Angela Castoldi, Stefan Balabanov, Bruce R. Blazar
Publikováno v:
Cell Metabolism
Summary How cells adapt metabolism to meet demands is an active area of interest across biology. Among a broad range of functions, the polyamine spermidine is needed to hypusinate the translation factor eukaryotic initiation factor 5A (eIF5A). We sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24bb9061e9b120f7fcc36a04cbbe2d8c
https://hdl.handle.net/21.11116/0000-0004-A643-521.11116/0000-0006-40A4-8
https://hdl.handle.net/21.11116/0000-0004-A643-521.11116/0000-0006-40A4-8
Autor:
Tuhama Chahoud, Patrick Ziegler, Jens Panse, Thomas Wilhelm, Marcus Schröder, Chris Meier, Valeska Wiehle, Melanie Braig, Matthias Rarey, Susanne Ziegler, Nora Pällman, Stefan Balabanov, Adrian Kolodzik, Joachim Hauber, Tim H. Brümmendorf
Publikováno v:
Investigational New Drugs. 30:2274-2283
Effective inhibition of BCR-ABL tyrosine kinase activity with Imatinib represents a breakthrough in the treatment of patients with chronic myeloid leukemia (CML). However, more than 30 % of patients with CML in chronic phase do not respond adequately