Výsledky vyhledávání

Kras and Lkb1 mutations synergistically induce intraductal papillary mucinous neoplasm derived from pancreatic duct cells

Autor: Anne Couvelard, Isabelle Leclercq, Nora Meyers, Patrick Jacquemin, Mohamad Assi, Elsa Ghurburrun, Jérôme Cros, Mina Komuta, Louis Collet, Pieter Demetter, Boris Pirlot, Ivan Borbath, Frédéric P. Lemaigre

Publikováno v: Gut, Vol. 69, no. 4, p. 704-714 (2020)

ObjectivePancreatic cancer can arise from precursor lesions called intraductal papillary mucinous neoplasms (IPMN), which are characterised by cysts containing papillae and mucus-producing cells. The high frequency of KRAS mutations in IPMN and histo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f8f4108c9e486c35ee2eadef2faa17a
https://hdl.handle.net/2078.1/216675

Zobrazit plný text záznamu

Differential impact of the ERBB receptors EGFR and ERBB2 on the initiation of precursor lesions of pancreatic ductal adenocarcinoma

Autor: Claude Gérard, Nora Meyers, Patrick Jacquemin, Frédéric P. Lemaigre

Publikováno v: Scientific Reports, Vol. 10, no.1, p. 5241 (2020)
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)

Earlier diagnosis of pancreatic ductal adenocarcinoma (PDAC) requires better understanding of the mechanisms driving tumorigenesis. In this context, depletion of Epidermal Growth Factor Receptor (EGFR) is known to impair development of PDAC-initiatin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d2a6d6d2f7414c144f0e6ab10871fc1
https://hdl.handle.net/2078.1/230708

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání