Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Nora M Gerhards"'
Autor:
César Muñoz-Fontela, Lina Widerspick, Randy A Albrecht, Martin Beer, Miles W Carroll, Emmie de Wit, Michael S Diamond, William E Dowling, Simon G P Funnell, Adolfo García-Sastre, Nora M Gerhards, Rineke de Jong, Vincent J Munster, Johan Neyts, Stanley Perlman, Douglas S Reed, Juergen A Richt, Ximena Riveros-Balta, Chad J Roy, Francisco J Salguero, Michael Schotsaert, Lauren M Schwartz, Robert A Seder, Joaquim Segalés, Seshadri S Vasan, Ana María Henao-Restrepo, Dan H Barouch
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1, p e1010161 (2022)
The global response to Coronavirus Disease 2019 (COVID-19) is now facing new challenges such as vaccine inequity and the emergence of SARS-CoV-2 variants of concern (VOCs). Preclinical models of disease, in particular animal models, are essential to
Externí odkaz:
https://doaj.org/article/2e0188b1403e45f2bd75009acab0b6c7
Autor:
Rineke de Jong, Wout Nuiten, Albertjan ter Heide, Wilfred Hamstra, Sandra Vreman, Nadia Oreshkova, Katrin E. Wiese, Nora M. Gerhards
Publikováno v:
Viruses, Vol 16, Iss 7, p 1022 (2024)
Pulmonary function examinations are critical to assess respiratory disease severity in patients. In preclinical rodent models of viral respiratory infections, however, disease is frequently evaluated based on virological, pathological and/or surrogat
Externí odkaz:
https://doaj.org/article/84dfa31aa4f34eb785cf4d34892bab53
Autor:
Nora M. Gerhards, Jose L. Gonzales, Sandra Vreman, Lars Ravesloot, Judith M. A. van den Brand, Harmen P. Doekes, Herman F. Egberink, Arjan Stegeman, Nadia Oreshkova, Wim H. M. van der Poel, Mart C. M. de Jong
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT The susceptibility of domestic cats to infection with SARS-CoV-2 has been demonstrated by several experimental studies and field observations. We performed an extensive study to further characterize the transmission of SARS-CoV-2 between cat
Externí odkaz:
https://doaj.org/article/0b450ae798c743c98e73b18751537a9b
Autor:
Sandra Vreman, Elisabeth M. D. L. van der Heijden, Lars Ravesloot, Irene S. Ludwig, Judith M. A. van den Brand, Frank Harders, Andries A. Kampfraath, Herman F. Egberink, Jose L. Gonzales, Nadia Oreshkova, Femke Broere, Wim H. M. van der Poel, Nora M. Gerhards
Publikováno v:
Viruses, Vol 15, Iss 5, p 1052 (2023)
Several reports demonstrated the susceptibility of domestic cats to SARS-CoV-2 infection. Here, we describe a thorough investigation of the immune responses in cats after experimental SARS-CoV-2 inoculation, along with the characterization of infecti
Externí odkaz:
https://doaj.org/article/a7de9a3a6eb444f4adf1e2c931fc23bb
Autor:
Paola Francica, Merve Mutlu, Vincent A. Blomen, Catarina Oliveira, Zuzanna Nowicka, Anika Trenner, Nora M. Gerhards, Peter Bouwman, Elmer Stickel, Maarten L. Hekkelman, Lea Lingg, Ismar Klebic, Marieke van de Ven, Renske de Korte-Grimmerink, Denise Howald, Jos Jonkers, Alessandro A. Sartori, Wojciech Fendler, J. Ross Chapman, Thijn Brummelkamp, Sven Rottenberg
Publikováno v:
Cell Reports, Vol 32, Iss 8, Pp 108068- (2020)
Summary: Using genome-wide radiogenetic profiling, we functionally dissect vulnerabilities of cancer cells to ionizing radiation (IR). We identify ERCC6L2 as a major determinant of IR response, together with classical DNA damage response genes and me
Externí odkaz:
https://doaj.org/article/c1546da443224518b9a9ceeee619ab96
Autor:
Nora M. Gerhards, Vincent A. Blomen, Merve Mutlu, Joppe Nieuwenhuis, Denise Howald, Charlotte Guyader, Jos Jonkers, Thijn R. Brummelkamp, Sven Rottenberg
Publikováno v:
Molecular Oncology, Vol 12, Iss 6, Pp 953-971 (2018)
The absence of biomarkers to accurately predict anticancer therapy response remains a major obstacle in clinical oncology. We applied a genome‐wide loss‐of‐function screening approach in human haploid cells to characterize genetic vulnerabiliti
Externí odkaz:
https://doaj.org/article/339adfac45064622b560e496f404b599
Autor:
Nora M. Gerhards, Jan B. W. J. Cornelissen, Lucien J. M. van Keulen, José Harders-Westerveen, Rianka Vloet, Bregtje Smid, Stéphanie Vastenhouw, Sophie van Oort, Renate W. Hakze-van der Honing, Jose L. Gonzales, Norbert Stockhofe-Zurwieden, Rineke de Jong, Wim H. M. van der Poel, Sandra Vreman, Jeroen Kortekaas, Paul J. Wichgers Schreur, Nadia Oreshkova
Publikováno v:
Pathogens, Vol 10, Iss 7, p 824 (2021)
In assessing species susceptibility for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and in the search for an appropriate animal model, multiple research groups around the world inoculated a broad range of animal species using variou
Externí odkaz:
https://doaj.org/article/a706bb632259444dad64cb088a022524
Autor:
Rik L. de Swart, Olav S. de Leeuw, Nadia Oreshkova, Nora M. Gerhards, Irina C. Albulescu, Sandra Vreman, José L. Gonzales, Riks Maas, Frank J.M. van Kuppeveld, Peter Soema, Berend-Jan Bosch, Ben P.H. Peeters
Publikováno v:
Vaccine 40 (2022) 33
Vaccine, 40(33), 4676-4681
Vaccine, 40(33), 4676-4681
The emergence of SARS-CoV-2 in December 2019 resulted in the COVID-19 pandemic. Recurring disease outbreaks repeatedly overloaded the public health sector and severely affected the global economy. We developed a candidate COVID-19 vaccine based on a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::969802814938e99d35b96baad1bfc0dc
https://doi.org/10.1016/j.vaccine.2022.07.005
https://doi.org/10.1016/j.vaccine.2022.07.005
Autor:
Nora M. Gerhards, Jose L. Gonzales, Sandra Vreman, Lars Ravesloot, Judith M. A. van den Brand, Harmen P. Doekes, Herman F. Egberink, Arjan Stegeman, Nadia Oreshkova, Wim H. M. van der Poel, Mart C. M. de Jong
The susceptibility of domestic cats to infection with SARS-CoV-2 has been demonstrated by several experimental studies and field observations. We performed an extensive study to further characterize the transmission of SARS-CoV-2 between cats, throug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cb4138d03ecc8d372e85c0bc40c1f75
https://doi.org/10.1101/2022.06.17.496600
https://doi.org/10.1101/2022.06.17.496600
Publikováno v:
Viruses
Domestic cats are susceptible to SARS-CoV-2 virus infection and given that they are in close contact with people, assessing the potential risk cats represent for the transmission and maintenance of SARS-CoV-2 is important. Assessing this risk implies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::28cb2be70db6a42ffbb6593440ec9748
https://pubmed.ncbi.nlm.nih.gov/34960749
https://pubmed.ncbi.nlm.nih.gov/34960749