Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Nora Lenkey"'
Autor:
Michele Gianatti, Anna Christina Garvert, Nora Lenkey, Nora Cecilie Ebbesen, Eivind Hennestad, Koen Vervaeke
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113109- (2023)
Summary: Neuronal signals encoding the animal’s position widely modulate neocortical processing. While these signals are assumed to depend on hippocampal output, their origin has not been investigated directly. Here, we asked which brain region sen
Externí odkaz:
https://doaj.org/article/b33e322c7d0943b282b0d7ae77ab069f
Publikováno v:
PLoS Computational Biology, Vol 6, Iss 6, p e1000818 (2010)
Sodium channels are one of the most intensively studied drug targets. Sodium channel inhibitors (e.g., local anesthetics, anticonvulsants, antiarrhythmics and analgesics) exert their effect by stabilizing an inactivated conformation of the channels.
Externí odkaz:
https://doaj.org/article/6de7b317868e4b38b7a15a42584df7bf
Autor:
Nora Lenkey, Robert Karoly, Peter Lukacs, E Sylvester Vizi, Morten Sunesen, Laszlo Fodor, Arpad Mike
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15568 (2010)
BACKGROUND: There is only one established drug binding site on sodium channels. However, drug binding of sodium channels shows extreme promiscuity: ∼25% of investigated drugs have been found to potently inhibit sodium channels. The structural diver
Externí odkaz:
https://doaj.org/article/c8bef075d65b408a8b782793ac3d6928
Publikováno v:
Journal of Neuroscience
CB1 cannabinoid receptors (CB1) are located at axon terminals and effectively control synaptic communication and thereby circuit operation widespread in the CNS. Although it is partially uncovered how CB1 activation leads to the reduction of synaptic
Autor:
Bernadett K. Szasz, Dalma Kurkó, Nora Lenkey, Janos P. Kiss, László Fodor, József Nagy, E. Sylvester Vizi, Arpad Mike
Publikováno v:
Neurochemistry International. 60:170-176
Accumulating evidence has indicated the involvement of glutamatergic neurotransmission in the pathophysiology of excitotoxicity and in the mechanism of action of antidepressants. We have previously shown that tricyclic desipramine and the selective s
Autor:
Albert M. I. Barth, Bernadett K. Szasz, Balázs Lendvai, Orsolya Farkas, Zsolt Somogyvari, Arpad Mike, Nora Lenkey
Publikováno v:
Planta Medica. 74:1235-1239
In this study, an attempt was made to integrate the effects of GINKGO BILOBA extract (GBE) in different experimental systems (IN VITRO cochlea, brain slice preparations and cortical cell culture) to elucidate whether these processes converge to promo
Autor:
Gábor Szabó, Zoltan Nusser, Nora Lenkey, E. Sylvester Vizi, Norbert Hájos, Zoltán Máté, Tekla Kirizs, Noemi Holderith
Publikováno v:
Nature Communications. 6
Nature Communications 6, Article number: 6557 (2015); Published: 20 April 2015; Updated: 26 August 2015. In Fig. 1g of this Article, three data series were inadvertently omitted from the graph while the final version of the manuscript was prepared fo
Autor:
Zoltán Máté, Zoltan Nusser, Norbert Hájos, Nora Lenkey, Gábor Szabó, E. Sylvester Vizi, Noemi Holderith, Tekla Kirizs
Publikováno v:
Nature Communications
The release of GABA from cholecystokinin-containing interneurons is modulated by type-1 cannabinoid receptors (CB1). Here we tested the hypothesis that the strength of CB1-mediated modulation of GABA release is related to the CB1 content of axon term
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a57a4931ab70d860723cc759d18a2ac
https://aperta.ulakbim.gov.tr/record/81947
https://aperta.ulakbim.gov.tr/record/81947
Autor:
Gergely G, Szabó, Nora, Lenkey, Noemi, Holderith, Tibor, Andrási, Zoltan, Nusser, Norbert, Hájos
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 34(23)
CB(1) cannabinoid receptors (CB(1)) are located at axon terminals and effectively control synaptic communication and thereby circuit operation widespread in the CNS. Although it is partially uncovered how CB(1) activation leads to the reduction of sy
Publikováno v:
Neuropharmacology. 60(1)
Sodium channels are inhibited by a chemically diverse group of compounds. In the last decade entirely new structural classes with superior properties have been discovered, and novel therapeutic uses of sodium channel inhibitors (SCIs) have been sugge