Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Nora L. Krutz"'
Autor:
Nora L. Krutz, Ian Kimber, Jason Winget, Minh N. Nguyen, Vachiranee Limviphuvadh, Sebastian Maurer-Stroh, Catherine Mahony, G. Frank Gerberick
Publikováno v:
Journal of Immunotoxicology, Vol 21, Iss 1 (2024)
AbstractThe demand for botanicals and natural substances in consumer products has increased in recent years. These substances usually contain proteins and these, in turn, can pose a risk for immunoglobulin E (IgE)-mediated sensitization and allergy.
Externí odkaz:
https://doaj.org/article/2320296b9cd242919a6fd10a22092c29
Autor:
Nora L. Krutz, Ian Kimber, Jason Winget, Minh N. Nguyen, Vachiranee Limviphuvadh, Sebastian Maurer-Stroh, Catherine Mahony, G. Frank Gerberick
Publikováno v:
Frontiers in Allergy, Vol 4 (2023)
Foreign proteins are potentially immunogenic, and a proportion of these are able to induce immune responses that result in allergic sensitization. Subsequent exposure of sensitized subjects to the inducing protein can provoke a variety of allergic re
Externí odkaz:
https://doaj.org/article/abbe08ec6a654e31a21f3430d835d835
Autor:
Nikaeta, Sadekar, Fanny, Boisleve, Wolfgang, Dekant, Allison D, Fryer, G Frank, Gerberick, Peter, Griem, Christina, Hickey, Nora L, Krutz, Olga, Lemke, Cecile, Mignatelli, Reynold, Panettieri, Kent E, Pinkerton, Kevin J, Renskers, Paul, Sterchele, Simone, Switalla, Matthew, Wolter, Anne Marie, Api
Publikováno v:
Critical Reviews in Toxicology. 51:792-804
The induction of immunological responses that trigger bio-physiological symptoms in the respiratory tract following repeated exposure to a substance, is known as respiratory sensitization. The inducing compound is known as a respiratory sensitizer. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cbe487e3aa84037d893077b59894206
https://doi.org/10.1080/10408444.2021.2024142
https://doi.org/10.1080/10408444.2021.2024142
Autor:
Petra S. Kern, Kim Ellingson, Yuan Gao, Nora L. Krutz, Kady Krivos, Mike Quijano, Yan Xu, Cindy A. Ryan
Publikováno v:
Toxicology in Vitro. 90:105591
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::216d1f8d7b6404f8a3b5db7d6fc726f0
https://doi.org/10.1016/j.tiv.2023.105591
https://doi.org/10.1016/j.tiv.2023.105591
Autor:
Minh N Nguyen, Nora L Krutz, Vachiranee Limviphuvadh, Andreas L Lopata, G Frank Gerberick, Sebastian Maurer-Stroh
Publikováno v:
Nucleic acids research.
Proteins in food and personal care products can pose a risk for an immediate immunoglobulin E (IgE)-mediated allergic response. Bioinformatic tools can assist to predict and investigate the allergenic potential of proteins. Here we present AllerCatPr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e90da63b22dff7617f190343244ecb
https://pubmed.ncbi.nlm.nih.gov/35640594
https://pubmed.ncbi.nlm.nih.gov/35640594
Autor:
Ian Kimber, Jason M. Winget, Sebastian Maurer-Stroh, Cindy A. Ryan, Rebecca J. Dearman, Rohan Lalith Wimalasena, G. Frank Gerberick, Nora L Krutz
Publikováno v:
Toxicological Sciences. 170:210-222
Use of botanicals and natural substances in consumer products has increased in recent years. Such extracts can contain protein that may theoretically represent a potential risk of IgE-mediated allergy. No method has yet been generally accepted or val
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4864c5eee53391b6511a1a80af08942
https://doi.org/10.1093/toxsci/kfz078
https://doi.org/10.1093/toxsci/kfz078
Autor:
Vithiagaran Gunalan, Nora L Krutz, Matthew Nguyen, Petra S. Kern, Frank Eisenhaber, Vachiranee Limviphuvadh, G. Frank Gerberick, Sebastian Maurer-Stroh
Publikováno v:
Bioinformatics
Motivation Due to the risk of inducing an immediate Type I (IgE-mediated) allergic response, proteins intended for use in consumer products must be investigated for their allergenic potential before introduction into the marketplace. The FAO/WHO guid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff5fb56a7012bccf7120ec587f677ada
https://doi.org/10.1093/bioinformatics/btz029
https://doi.org/10.1093/bioinformatics/btz029
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 182(2)
Interest in the development of methods to evaluate the respiratory sensitization potential of low-molecular weight chemicals continues, but no method has yet been generally accepted or validated. A lack of chemical reference standards, together with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6171ade73af8e87f507bed2201d2b228
https://pubmed.ncbi.nlm.nih.gov/34003265
https://pubmed.ncbi.nlm.nih.gov/34003265
Publikováno v:
Critical reviews in toxicology. 50(6)
The use of proteins and protein-containing materials in a variety of industrial and commercial products is increasing, with applications in pharmaceuticals, agrochemicals and consumer and personal care products. As a consequence there is a need to en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e624abb24d8ebf6a9db1d7ca609cae7
https://pubmed.ncbi.nlm.nih.gov/32729356
https://pubmed.ncbi.nlm.nih.gov/32729356
Autor:
G.F. Gerberick, Jason M. Winget, Cindy A. Ryan, Ian Kimber, Rohan Lalith Wimalasena, Nora L Krutz, Rebecca J. Dearman, Sebastian Maurer-Stroh
Publikováno v:
Toxicology Letters. 295:S73-S74
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b9aa370a7ff976885235e8a1c219810
https://doi.org/10.1016/j.toxlet.2018.06.531
https://doi.org/10.1016/j.toxlet.2018.06.531