Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Nora Kory"'
Autor:
Nora Kory, Susanne Grond, Siddhesh S. Kamat, Zhihuan Li, Natalie Krahmer, Chandramohan Chitraju, Ping Zhou, Florian Fröhlich, Ivana Semova, Christer Ejsing, Rudolf Zechner, Benjamin F. Cravatt, Robert V. Farese, Jr., Tobias C. Walther
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 1, Pp 226-235 (2017)
Variations in the gene LDAH (C2ORF43), which encodes lipid droplet-associated hydrolase (LDAH), are among few loci associated with human prostate cancer. Homologs of LDAH have been identified as proteins of lipid droplets (LDs). LDs are cellular orga
Externí odkaz:
https://doaj.org/article/3ec52a4ce7e4467191376e0d18ab2f9f
Autor:
Erin Currie, Xiuling Guo, Romain Christiano, Chandramohan Chitraju, Nora Kory, Kenneth Harrison, Joel Haas, Tobias C. Walther, Robert V. Farese, Jr.
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 7, Pp 1465-1477 (2014)
Accurate protein inventories are essential for understanding an organelle's functions. The lipid droplet (LD) is a ubiquitous intracellular organelle with major functions in lipid storage and metabolism. LDs differ from other organelles because they
Externí odkaz:
https://doaj.org/article/38e773b11d0b498bb87e2ac1fb8ce5eb
Autor:
Florian Fröhlich, Constance Petit, Nora Kory, Romain Christiano, Hans-Kristian Hannibal-Bach, Morven Graham, Xinran Liu, Christer S Ejsing, Robert V Farese Jr, Tobias C Walther
Publikováno v:
eLife, Vol 4 (2015)
Sphingolipids are abundant membrane components and important signaling molecules in eukaryotic cells. Their levels and localization are tightly regulated. However, the mechanisms underlying this regulation remain largely unknown. In this study, we id
Externí odkaz:
https://doaj.org/article/0230e65b8c7b4312b88ff014183e4da8
Autor:
Liron Bar-Peled, Nora Kory
Publikováno v:
Nat Metab
Metabolism has historically been studied at the levels of whole cells, whole tissues and whole organisms. As a result, our understanding of how compartmentalization-the spatial and temporal separation of pathways and components-shapes organismal meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36f536c183b923b676f136543f069051
https://doi.org/10.1038/s42255-022-00645-2
https://doi.org/10.1038/s42255-022-00645-2
Publikováno v:
Semin. Cell Dev. Biol. 108, 72-81 (2020)
In cells, lipids are stored in lipid droplets, dynamic organelles that adapt their size, abundance, lipid and protein composition and organelle interactions to metabolic changes. Lipid droplet accumulation in the liver is the hallmark of non-alcoholi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8506eb08f9961d0433817ba3a8da7625
https://doi.org/10.1016/j.semcdb.2020.04.011
https://doi.org/10.1016/j.semcdb.2020.04.011
Autor:
Jordan Rossen, Alexandre Detappe, Mairead Reidy, John L. Markley, Mustafa Kocak, Prathapan Thiru, Kai Cai, Nora Kory, Irene M. Ghobrial, Guillaume Kugener, Weiwen Ying, Peter Tsvetkov, Luke Whitesell, Aviad Tsherniak, Zarina Brune, Susan Lindquist, Todd R. Golub, Sandro Santagata, Heather R. Keys
Publikováno v:
Nature chemical biology
The mechanisms by which cells adapt to proteotoxic stress are largely unknown, but are key to understanding how tumor cells, particularly in vivo, are largely resistant to proteasome inhibitors. Analysis of cancer cell lines, mouse xenografts and pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e43adcb5106a835f4ac5addc02c14a7e
http://europepmc.org/articles/PMC8183600
http://europepmc.org/articles/PMC8183600
Autor:
Vera Gorbunova, Marcus Buschbeck, Xiaolu A. Cambronne, Karthikeyani Chellappa, Daniela Corda, Juan Du, Marc Freichel, Jonathan Gigas, Alexander E. Green, Feng Gu, Iva Guberovic, Aravinthkumar Jayabalan, Imrankhan Khansahib, Sarmistha Mukherjee, Andrei Seluanov, Matthew A. Simon, Lars J. Sverkeli, Nora Kory, Daniel C. Levine, Ivan Matic, Andrey Nikiforov, Johannes G.M. Rack, Shin-Ichiro Imai, David A. Sinclair, Debra Toiber, Yongjuan Zhao, Raul Mostoslavsky, Lee Kraus, Andreas H. Guse
Publikováno v:
Aging
24924-24930
Aging (Albany NY)
24924-24930
Aging (Albany NY)
publishedVersion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c814ae682be5b29ae943a03cd6518b9
https://hdl.handle.net/11250/2988883
https://hdl.handle.net/11250/2988883
Autor:
Leyla Anne Akay, Susan Lindquist, Agnese Graziosi, Sebastian Boland, William T. Ralvenius, Valeriya Baru, Aleksandra Alicja Arczewska, Nora Kory, Julia Maeve Bonner, Elana Lockshin, Grzegorz Sienski, Caroline A. Lewis, Priyanka Narayan, Blerta Milo, Manolis Kellis, Liang He, David M. Sabatini, Li-Huei Tsai
Publikováno v:
Sci Transl Med
PMC
PMC
Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works The E4 allele of the apolipoprotein E gene (APOE) has been established as a geneti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a4318185a6e20804c536d843839fba1
http://hdl.handle.net/11585/854127
http://hdl.handle.net/11585/854127
Autor:
M. Guera, Nora Kory, Caroline A. Lewis, Sze Ham Chan, N. Arp, N. Jankovic, Gyan Prakash, S. van der Rijt, Izabella A. Pena, Tenzin Kunchok, J. uit de Bos, David M. Sabatini
The nicotinamide adenine dinucleotide (NAD+/NADH) pair is a cofactor in redox reactions and is particularly critical in mitochondria as it connects substrate oxidation by the tricarboxylic acid (TCA) cycle to ATP generation by the electron transport
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8addbabde904852d8bbc31dd133649b3
https://doi.org/10.1101/2020.08.28.267252
https://doi.org/10.1101/2020.08.28.267252
Autor:
Jelmi uit de Bos, Sanne van der Rijt, Izabella A. Pena, Gyan Prakash, Caroline A. Lewis, Nevena Jankovic, Nora Kory, David M. Sabatini, Sze Ham Chan, Nicholas Arp, Tenzin Kunchok, Miriam Güra
Publikováno v:
Trends Biochem Sci
Science Advances
Science Advances
We demystify how mitochondria obtain NAD, revealing that MCART1/SCL25A51 is required for NAD transport into mitochondria.
The nicotinamide adenine dinucleotide (NAD+/NADH) pair is a cofactor in redox reactions and is particularly critical in mit
The nicotinamide adenine dinucleotide (NAD+/NADH) pair is a cofactor in redox reactions and is particularly critical in mit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cde40ae90e07e38560553ec72cc3c642
https://pubmed.ncbi.nlm.nih.gov/33618948
https://pubmed.ncbi.nlm.nih.gov/33618948