Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Nora Hagelberg"'
Publikováno v:
Pain. 162(1)
Patients with chronic pain have complex pain profiles and associated problems. Subgroup analysis can help identify key problems. We used a data-based approach to define pain phenotypes and their most relevant associated problems in 320 patients under
Autor:
Klaus T. Olkkola, Heikki Huhtinen, P. Varpe, Nora Hagelberg, E Karru, Mari Fihlman, Teijo I. Saari
Publikováno v:
Scientific Reports
Since patients often experience pain and unpleasantness during a colonoscopy, the present study aimed to evaluate the efficacy and safety of sublingually administered fentanyl tablets for pain treatment. Furthermore, since the use of intravenous drug
Publikováno v:
European Journal of Pharmacology. 834:337-345
Here we review the literature assessing the roles of the brain dopaminergic and serotonergic systems in the modulation of pain as revealed by in vivo human studies using positron emission tomography. In healthy subjects, dopamine D-2/D-3 receptor ava
Autor:
Jouko Laitila, Teijo I. Saari, Kari Laine, Tuija Hemmilä, Mari Fihlman, Klaus T. Olkkola, Nora Hagelberg, Janne T. Backman, Pertti J. Neuvonen
Publikováno v:
European Journal of Clinical Pharmacology. 74:1615-1622
Buprenorphine has low oral bioavailability. Regardless of sublingual administration, a notable part of buprenorphine is exposed to extensive first-pass metabolism by the cytochrome P450 (CYP) 3A4. As drug interaction studies with buprenorphine are li
Autor:
Riku Aantaa, Elise Syrjälä, Arman Anzanpour, Mingzhe Jiang, Amir M. Rahmani, Virpi Terävä, Riitta Mieronkoski, Nora Hagelberg, Sanna Salanterä, Pasi Liljeberg
Publikováno v:
Journal of Clinical Monitoring and Computing
Current acute pain intensity assessment tools are mainly based on self-reporting by patients, which is impractical for non-communicative, sedated or critically ill patients. In previous studies, various physiological signals have been observed qualit
Autor:
Tero Taiminen, Nora Hagelberg, Salla Lamusuo, Jussi Hirvonen, Riitta Parkkola, Satu K. Jääskeläinen, Semi Helin, Arja Virtanen, Ilkka K. Martikainen, Pauliina Lindholm, Antti Pertovaara, Jarmo Hietala
Publikováno v:
European Journal of Pain. 21:1505-1515
Background Repetitive transcranial magnetic stimulation (rTMS) at M1/S1 cortex has been shown to alleviate neuropathic pain. Objectives To investigate the possible neurobiological correlates of cortical neurostimulation for the pain relief. Methods W
Autor:
Pertti J. Neuvonen, Klaus T. Olkkola, Nora Hagelberg, Kristiina Kuusniemi, Jouko Laitila, Janne T. Backman, Tuija Hemmilä, Mari Fihlman, Kari Laine, Teijo I. Saari
Publikováno v:
European Journal of Clinical Pharmacology. 72:1363-1371
This study aimed to determine possible effects of voriconazole and posaconazole on the pharmacokinetics and pharmacological effects of sublingual buprenorphine. We used a randomized, placebo-controlled crossover study design with 12 healthy male volu
Publikováno v:
Clinical Pharmacokinetics. 55:1059-1077
Ketamine is a phencyclidine derivative, which functions primarily as an antagonist of the N-methyl-D-aspartate receptor. It has no affinity for gamma-aminobutyric acid receptors in the central nervous system. Ketamine shows a chiral structure consist
Autor:
Nora Hagelberg
Publikováno v:
Scandinavian journal of pain. 1(4)
Physiological, psychological and social factors interact in a comlex manner to form an individual experience of pain. Emotional nd cognitive factors modulate pain experience to elicit a behavoral response to pain which, in turn, is modified by social
Autor:
Tero Taiminen, Jarmo Hietala, Antti Pertovaara, Salla Lamusuo, Nora Hagelberg, Riitta Parkkola, Arja Virtanen, Ullamari Pesonen, Ari Lahti, Pauliina Lindholm, Satu K. Jääskeläinen, Heli Forssell
Publikováno v:
Pain. 156:1276-1283
High-frequency repetitive transcranial magnetic stimulation (rTMS) of the motor cortex has analgesic effect; however, the efficacy of other cortical targets and the mode of action remain unclear. We examined the effects of rTMS in neuropathic orofaci