Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Nora Fernández‐Jiménez"'
Autor:
Itziar González‐Moro, Koldo Garcia‐Etxebarria, Luis Manuel Mendoza, Nora Fernández‐Jiménez, Jon Mentxaka, Ane Olazagoitia‐Garmendia, María Nicol Arroyo, Toshiaki Sawatani, Cristina Moreno‐Castro, Chiara Vinci, Anne Op de Beek, Miriam Cnop, Mariana Igoillo‐Esteve, Izortze Santin
Publikováno v:
Advanced Science, Vol 10, Iss 25, Pp n/a-n/a (2023)
Abstract Type 1 diabetes (T1D) is a complex autoimmune disease that develops in genetically susceptible individuals. Most T1D‐associated single nucleotide polymorphisms (SNPs) are located in non‐coding regions of the human genome. Interestingly,
Externí odkaz:
https://doaj.org/article/e0b08b72f8934629b39760d37febee3a
Autor:
Itziar González-Moro, Koldo Garcia-Etxebarria, Luis Manuel Mendoza, Nora Fernández-Jiménez, Jon Mentxaka-Salgado, Ane Olazagoitia-Garmendia, María Nicol Arroyo, Toshiaki Sawatani, Anne Op de Beek, Miriam Cnop, Mariana Igoillo-Esteve, Izortze Santin
SummaryType 1 diabetes-associated single nucleotide polymorphisms are mainly located in non-coding regions of the human genome. Single nucleotide polymorphisms located in long non-coding RNAs may result in the disruption of their secondary structure,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed04dc76b7bd0a247bac8f6027de8f5e
https://doi.org/10.1101/2022.12.01.518685
https://doi.org/10.1101/2022.12.01.518685
Evaluating the association between placenta DNA methylation and cognitive functions in the offspring
Autor:
Laia Diez-Ahijado, Ariadna Cilleros-Portet, Nora Fernández-Jimenez, Mariana F. Fernández, Monica Guxens, Jordi Julvez, Sabrina Llop, Maria-Jose Lopez-Espinosa, Mikel Subiza-Pérez, Manuel Lozano, Jesus Ibarluzea, Jordi Sunyer, Mariona Bustamante, Marta Cosin-Tomas
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The placenta plays a crucial role in protecting the fetus from environmental harm and supports the development of its brain. In fact, compromised placental function could predispose an individual to neurodevelopmental disorders. Placental ep
Externí odkaz:
https://doaj.org/article/9783c3ef759f4b7dbc1c2fa1f7710f24
Autor:
Alba Hernangomez-Laderas, Ariadna Cilleros-Portet, Silvia Martínez Velasco, Sergi Marí, María Legarda, Bárbara Paola González-García, Carlos Tutau, Iraia García-Santisteban, Iñaki Irastorza, Nora Fernandez-Jimenez, Jose Ramon Bilbao
Publikováno v:
Biology of Sex Differences, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Background Celiac disease (CeD) is an immune-mediated disorder that develops in genetically predisposed individuals upon gluten consumption. HLA risk alleles explain 40% of the genetic component of CeD, so there have been continuing efforts
Externí odkaz:
https://doaj.org/article/474b8c1519674269842afd2c56b9e227
Autor:
Gerard Badia-Bringué, Maria Canive, Nora Fernandez-Jimenez, José Luis Lavín, Rosa Casais, Cristina Blanco-Vázquez, Patricia Vázquez, Almudena Fernández, Jose Ramón Bilbao, Joseba M. Garrido, Ramón A. Juste, Oscar González-Recio, Marta Alonso-Hearn
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Genome-wide association studies (GWAS) have identified host genetic variants associated with paratuberculosis (PTB) susceptibility. Most of the GWAS-identified SNPs are in non-coding regions. Connecting these non-coding variants and downstre
Externí odkaz:
https://doaj.org/article/af6b21caaa5a42d5b19d550d12a0217b
Autor:
Nora Fernandez-Jimenez, Ruby Fore, Ariadna Cilleros-Portet, Johanna Lepeule, Patrice Perron, Tuomas Kvist, Fu-Ying Tian, Corina Lesseur, Alexandra M. Binder, Manuel Lozano, Jordi Martorell-Marugán, Yuk J. Loke, Kelly M. Bakulski, Yihui Zhu, Anne Forhan, Sara Sammallahti, Todd M. Everson, Jia Chen, Karin B. Michels, Thalia Belmonte, Pedro Carmona-Sáez, Jane Halliday, M. Daniele Fallin, Janine M. LaSalle, Jorg Tost, Darina Czamara, Mariana F. Fernández, Antonio Gómez-Martín, Jeffrey M. Craig, Beatriz Gonzalez-Alzaga, Rebecca J. Schmidt, John F. Dou, Evelyne Muggli, Marina Lacasaña, Martine Vrijheid, Carmen J. Marsit, Margaret R. Karagas, Katri Räikkönen, Luigi Bouchard, Barbara Heude, Loreto Santa-Marina, Mariona Bustamante, Marie-France Hivert, Jose Ramon Bilbao
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
A meta-analysis of pre-pregnancy maternal body mass index (ppBMI) and placental DNA methylation from 2631 mother-child pairs identifies 27 CpG sites associated with ppBMI, providing insight into how maternal obesity could be associated with metabolic
Externí odkaz:
https://doaj.org/article/25f6e68216ef415aa23b5efa7f8762a9
Autor:
Bárbara P. González-García, Sergi Marí, Ariadna Cilleros-Portet, Alba Hernangomez-Laderas, Nora Fernandez-Jimenez, Iraia García-Santisteban, Jose Ramon Bilbao
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundCeliac Disease (CeD) is an autoimmune disorder triggered by gluten intake in genetically susceptible individuals. Highest risk individuals are homozygous for the Human Leucocyte Antigen (HLA) DQ2.5 haplotype or DQ2.5/DQ2.2 heterozygous. Bot
Externí odkaz:
https://doaj.org/article/c1c166cae0af4e7f9131f6113df280d3
Autor:
S. Olaechea-Lázaro, I. García-Santisteban, J. R. Pineda, I. Badiola, S. Alonso, Jose Ramon Bilbao, Nora Fernandez-Jimenez
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-6 (2021)
Abstract Background Quantitative, reverse transcription PCR (qRT-PCR) is currently the gold-standard for SARS-CoV-2 detection and it is also used for detection of other virus. Manual data analysis of a small number of qRT-PCR plates per day is a rela
Externí odkaz:
https://doaj.org/article/ee987734f93445bb918ea610fb7929cf
Autor:
Todd M. Everson, Marta Vives-Usano, Emie Seyve, Andres Cardenas, Marina Lacasaña, Jeffrey M. Craig, Corina Lesseur, Emily R. Baker, Nora Fernandez-Jimenez, Barbara Heude, Patrice Perron, Beatriz Gónzalez-Alzaga, Jane Halliday, Maya A. Deyssenroth, Margaret R. Karagas, Carmen Íñiguez, Luigi Bouchard, Pedro Carmona-Sáez, Yuk J. Loke, Ke Hao, Thalia Belmonte, Marie A. Charles, Jordi Martorell-Marugán, Evelyne Muggli, Jia Chen, Mariana F. Fernández, Jorg Tost, Antonio Gómez-Martín, Stephanie J. London, Jordi Sunyer, Carmen J. Marsit, Johanna Lepeule, Marie-France Hivert, Mariona Bustamante
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Maternal smoking during pregnancy contributes to poor birth outcomes. Here the authors perform a meta-analysis of the associations between maternal smoking during pregnancy and placental DNA methylation and identify links between these and poor birth
Externí odkaz:
https://doaj.org/article/dc8ffa9450d144648dc5bb3dac95b454
Autor:
Maria Canive, Nora Fernandez-Jimenez, Rosa Casais, Patricia Vázquez, José Luis Lavín, José Ramón Bilbao, Cristina Blanco-Vázquez, Joseba M. Garrido, Ramón A. Juste, Marta Alonso-Hearn
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Although genome-wide association studies have identified single nucleotide polymorphisms (SNPs) associated with the susceptibility to Mycobacterium avium subsp. paratuberculosis (MAP) infection, only a few functional mutations for bovine par
Externí odkaz:
https://doaj.org/article/4095e9afd7c24a33a653aca55989d50f