Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Nora Diéguez-Martínez"'
Autor:
Andrés Gámez-García, Idoia Bolinaga-Ayala, Guillermo Yoldi, Sergio Espinosa-Gil, Nora Diéguez-Martínez, Elisabet Megías-Roda, Pau Muñoz-Guardiola, Jose M. Lizcano
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Autophagy is a highly conserved intracellular process that preserves cellular homeostasis by mediating the lysosomal degradation of virtually any component of the cytoplasm. Autophagy is a key instrument of cellular response to several stresses, incl
Externí odkaz:
https://doaj.org/article/b087629e9a314cc7945f694a47bb7246
Autor:
Nora Diéguez-Martínez, Sergio Espinosa-Gil, Guillermo Yoldi, Elisabet Megías-Roda, Idoia Bolinaga-Ayala, Maria Viñas-Casas, Gokhan Gorgisen, Inés Domingo-Ortí, Héctor Pérez-Montoyo, Jose R. Bayascas, Eva Colas, Xavier Dolcet, Jose M. Lizcano
Publikováno v:
Scientia
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Apoptosis; Endometrial cancer; Map kinase Apoptosis; Cáncer endometrial; Mapa quinasa Apoptosi; Càncer d'endometri; Mapa quinasa Endometrial cancer (EC) is the most common type of gynecologic cancer in women of developed countries. Despite surgery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ee209282eb349c6036150295fb11f1b
https://hdl.handle.net/11351/8468
https://hdl.handle.net/11351/8468
Autor:
Nora Diéguez-Martínez, Héctor Pérez-Montoyo, Guillermo Velasco, Ana Oaknin, Josefina Casas, Tatiana Erazo, Carles Domenech, Pau Muñoz-Guardiola, Cristina Muñoz-Pinedo, Sonia Solé, Guillermo Yoldi, Margarita Romeo, Teresa Moran, Miguel F. Segura, Marc Yeste-Velasco, Gemma Fabriàs, Joaquim Bosch-Barrera, José Luis Abad, Elisabet Megías-Roda, Sergio Espinosa-Gil, Jose M. Lizcano, Jose Alfon
Publikováno v:
Autophagy
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Digital.CSIC. Repositorio Institucional del CSIC
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Digital.CSIC. Repositorio Institucional del CSIC
ABTL0812 is a first-in-class small molecule with anti-cancer activity, which is currently in clinical evaluation in a phase 2 trial in patients with advanced endometrial and squamous non-small cell lung carcinoma (NCT03366480). Previously, we showed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b4cf24fd82ac32523d794c3dd89e59
https://doi.org/10.1080/15548627.2020.1761651
https://doi.org/10.1080/15548627.2020.1761651
Autor:
Charles A. C. Williams, Diana O. Rios-Szwed, Helen A. Brown, Houjiang Zhou, Greg M. Findlay, Marios P. Stavridis, Saria Mansoor, Julien Peltier, Jose M. Lizcano, Matthias Trost, Robert Gourlay, Liam McMulkin, Rosalia Fernandez-Alonso, Rachel Toth, Nora Diéguez-Martínez
Publikováno v:
Biochemical Journal
The ERK5 MAP kinase signalling pathway drives transcription of naïve pluripotency genes in mouse Embryonic Stem Cells (mESCs). However, how ERK5 impacts on other aspects of mESC biology has not been investigated. Here, we employ quantitative proteom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a372c7a259282ccaabb9dcc4974f4525
https://pubmed.ncbi.nlm.nih.gov/34780645
https://pubmed.ncbi.nlm.nih.gov/34780645
Autor:
Liam McMulkin, Charles A. C. Williams, Rosalia Fernandez-Alonso, Houjiang Zhou, Robert Gourlay, Jose M. Lizcano, Rachel Toth, Greg M. Findlay, Saria Mansoor, Diana O. Rios-Szwed, Matthias Trost, Nora Diéguez-Martínez, Marios P. Stavridis, Julien Peltier, Helen A. Brown
SummaryThe ERK5 MAP kinase signalling pathway drives transcription of naïve pluripotency genes in mouse Embryonic Stem Cells (mESCs). However, how ERK5 impacts on other aspects of mESC biology has not been investigated. Here, we employ quantitative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80ad83f3a3e983fe2fc872656dd61f88
https://doi.org/10.1101/2021.03.29.435803
https://doi.org/10.1101/2021.03.29.435803
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2203 (2020)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Volume 21
Issue 6
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2203 (2020)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Volume 21
Issue 6
The MAP kinase ERK5 contains an N-terminal kinase domain and a unique C-terminal tail including a nuclear localization signal and a transcriptional activation domain. ERK5 is activated in response to growth factors and stresses and regulates transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dbe0756e41780d42a9cd308ad8f3065
https://ddd.uab.cat/record/241133
https://ddd.uab.cat/record/241133
Autor:
Sergio Espinosa-Gil, Jose M. Lizcano, Carles Domenech, Miguel F. Segura, Tatiana Erazo, Guillermo Velasco, Héctor Pérez-Montoyo, Nora Diéguez-Martínez, Pau Muñoz-Guardiola, Josefina Casas, Jose Alfon, Cristina Muñoz-Pinedo, Elisabet Megías-Roda, Marc Yeste-Velasco, Sonia Solé-Sánchez, Gemma Fabriàs, Guillermo Yoldi
Publikováno v:
Cancer Research. 80:1234-1234
ABTL0812 is a first-in-class small molecule with anticancer activity currently in Phase 2a clinical evaluation in patients with advanced endometrial and squamous NSCLC. We have previously described that ABTL0812 induces TRIB3 pseudokinase expression,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::289155addffde9d7684c473b69333b6f
https://doi.org/10.1158/1538-7445.am2020-1234
https://doi.org/10.1158/1538-7445.am2020-1234