Zobrazeno 1 - 10
of 4 585
pro vyhledávání: '"Nora D"'
Autor:
Andrew C. Kelleher, Torben D. Pearson, Joseph Ramsey, Wenjing Zhao, Kelly A. O’Conor, Abolghasem Bakhoda, Tyler Stodden, Min Guo, Seth M. Eisenberg, Sarthak V. Shah, Michael L. Freaney, Woochan Kim, Yeona Kang, Dardo Tomasi, Christopher Johnson, Chung-An Fang, Nora D. Volkow, Sung Won Kim
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract [11C]Carfentanil ([11C]CFN) is the only selective carbon-11 labeled radiotracer currently available for positron emission tomography (PET) imaging of mu opioid receptors (MORs). Though used extensively in clinical research, [11C]CFN has not
Externí odkaz:
https://doaj.org/article/4315cbf1a7754fb7b3963a6483ef4acf
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Alcohol use disorders are among the top causes of the global burden of disease, yet therapeutic interventions are limited. Reduced desire to drink in patients treated with semaglutide has raised interest regarding its potential therapeutic b
Externí odkaz:
https://doaj.org/article/a0ac78a2695f46ccbf36bc7b23fe8d22
Autor:
Nora D. Volkow, Joshua A. Gordon, Diana W. Bianchi, Michael F. Chiang, Janine A. Clayton, William M. Klein, George F. Koob, Walter J. Koroshetz, Eliseo J. Pérez-Stable, Jane M. Simoni, Bruce J. Tromberg, Richard P. Woychik, Rebecca Hommer, Erica L. Spotts, Benjamin Xu, Julia L. Zehr, Katherine M. Cole, Gayathri J. Dowling, Michelle P. Freund, Katia D. Howlett, Chloe J. Jordan, Traci M. Murray, Vani Pariyadath, Janani Prabhakar, Michele L. Rankin, Christopher S. Sarampote, Susan R.B. Weiss
Publikováno v:
Developmental Cognitive Neuroscience, Vol 69, Iss , Pp 101423- (2024)
The human brain undergoes rapid development during the first years of life. Beginning in utero, a wide array of biological, social, and environmental factors can have lasting impacts on brain structure and function. To understand how prenatal and ear
Externí odkaz:
https://doaj.org/article/c628e88449864b67a8b01eb2762b6abb
Autor:
Dardo Tomasi, Nora D. Volkow
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Handedness develops early in life, but the structural and functional brain connectivity patterns associated with it remains unknown. Here we investigate associations between handedness and the asymmetry of brain connectivity in 9- to 10-year
Externí odkaz:
https://doaj.org/article/98ecc5b57d1747e8a1005b038ba3bdd5
Autor:
Peter Manza, Dardo Tomasi, Ehsan Shokri-Kojori, Rui Zhang, Danielle Kroll, Dana Feldman, Katherine McPherson, Catherine Biesecker, Evan Dennis, Allison Johnson, Kai Yuan, Wen-Tung Wang, Michele-Vera Yonga, Gene-Jack Wang, Nora D. Volkow
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract The faster a drug enters the brain, the greater its addictive potential, yet the brain circuits underlying the rate dependency to drug reward remain unresolved. With simultaneous PET-fMRI we linked dynamics of dopamine signaling, brain activ
Externí odkaz:
https://doaj.org/article/623f73d6b0514209a834c48f08dca9bc
Publikováno v:
Neuroscience Insights, Vol 19 (2024)
Non-fatal opioid overdoses are associated with significant morbidity. Hypoxic brain injury caused by opioid-induced respiratory depression is a key mechanism of such morbidity. For example, reports describe an amnestic syndrome in opioid users associ
Externí odkaz:
https://doaj.org/article/737c042ffd6e4c9ca5a51bef5de81972
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Cocaine is a highly addictive drug, and its use is associated with adverse medical consequences such as cerebrovascular accidents that result in debilitating neurological complications. Indeed, brain imaging studies have reported severe reductions in
Externí odkaz:
https://doaj.org/article/deb1520255bc43a38a5de885f93fd135
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
Background and aimsIncreasing evidence suggests that a ketogenic (high-fat, low-carbohydrate) diet (KD) intervention reduces alcohol withdrawal severity and alcohol craving in individuals with alcohol use disorder (AUD) by shifting brain energetics f
Externí odkaz:
https://doaj.org/article/ded28fcf4d4d4456a05f57db4c33f74d
Autor:
Ivan D. Montoya, Nora D. Volkow
Publikováno v:
Pharmacological Research, Vol 200, Iss , Pp 107078- (2024)
Substance use disorders (SUDs) and drug overdose are a public health emergency and safe and effective treatments are urgently needed. Developing new medications to treat them is expensive, time-consuming, and the probability of a compound progressing
Externí odkaz:
https://doaj.org/article/744c1aaa22bd47f78f172f786c4eafff
Autor:
Stefania Pianetti, Kathy D. Miller, Hannah H. Chen, Sandra Althouse, Sha Cao, Steven J. Michael, Gail E. Sonenshein, Nora D. Mineva
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background Breast malignancies are the predominant cancer-related cause of death in women. New methods of diagnosis, prognosis and treatment are necessary. Previously, we identified the breast cancer cell surface protein ADAM8 as a marker of
Externí odkaz:
https://doaj.org/article/5cc491d6eaf74f3fb9dbdc1607f532c5