Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nora Chouha"'
Autor:
Marina Wierz, Sandrine Pierson, Nora Chouha, Laurent Désaubry, Jean-Hugues François, Guy Berchem, Jerome Paggetti, Etienne Moussay
Publikováno v:
Haematologica, Vol 103, Iss 4 (2018)
Externí odkaz:
https://doaj.org/article/8ee90e57cd1d4aecacf2167cbc13d9cd
Autor:
Kota Ando, Chiami Moyama, Shota Ando, Keiko Taniguchi, Laurent Désaubry, Susumu Kageyama, Akihiro Kawauchi, Susumu Nakata, Hiroko Takagi, Hiromi, Nora Chouha, Ryohei Matsuda
Publikováno v:
Molecular Pharmacology. 101:78-86
Prohibitin-2 (PHB2) is a scaffold protein that has pleiotropic functions, which include interacting with γ-glutamylcyclotransferase (GGCT) in the cytoplasm and repressing the transcriptional activities of the p21Waf1/Cip (p21) gene in the nucleus. T
Autor:
Nora Chouha, Hussein Abou-Hamdan, Hajime Yurugi, Riku Yoshii, Hiromi Ii, Ahmad Najem, Ghanem E. Ghanem, Susumu Nakata, Krishnaraj Rajalingam, Yu Peng, Dong Wang, Canan G. Nebigil, Laurent Désaubry
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, 2022, 242, pp.114635. ⟨10.1016/j.ejmech.2022.114635⟩
European Journal of Medicinal Chemistry, 2022, 242, pp.114635. ⟨10.1016/j.ejmech.2022.114635⟩
Fluorizoline is a cytotoxic trifluorothiazoline that targets the scaffold proteins prohibitins-1 and -2 (PHB1/2) to inhibit the kinase C-RAF and promote the expression of the cyclin-dependent kinase inhibitor p21 to induce cancer cell death. In melan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cc9b51a7fa505ea1d0e6306f4d0fe36
https://hal.science/hal-03806694
https://hal.science/hal-03806694
Autor:
Thierry Cresteil, Embarek Bentouhami, Stéphan Vagner, Laurent Désaubry, Caroline Robert, Giuseppe Campiani, Caroline Welsch, Nora Chouha, Hassan Hammoud, Simone Brogi
Publikováno v:
The Open Medicinal Chemistry Journal. 12:74-83
In our quest to identify inhibitors of the eukaryotic translation initiation factor 4F (eIF4F), we serendipitously discovered a novel cytotoxic agent. Even though this compound did not inhibit translation, we explored the structural requirements for
Autor:
Franck Pinot, Amel Djehal, Nora Chouha, Sabria Elderwish, Laurent Désaubry, Peng Yu, Redouane Tabti, Dong Wang, Canan G. Nebigil
Publikováno v:
Bioorganic and Medicinal Chemistry Letters
Bioorganic and Medicinal Chemistry Letters, Elsevier, 2020, 30 (22), pp.127600. ⟨10.1016/j.bmcl.2020.127600⟩
Bioorganic & Medicinal Chemistry Letters
Bioorganic and Medicinal Chemistry Letters, 2020, 30 (22), pp.127600. ⟨10.1016/j.bmcl.2020.127600⟩
Bioorganic and Medicinal Chemistry Letters, Elsevier, 2020, 30 (22), pp.127600. ⟨10.1016/j.bmcl.2020.127600⟩
Bioorganic & Medicinal Chemistry Letters
Bioorganic and Medicinal Chemistry Letters, 2020, 30 (22), pp.127600. ⟨10.1016/j.bmcl.2020.127600⟩
Graphical abstract
Highlights • The stomatin/prohibitin/flotillin/HflK/C (SPFH) domain is present in archaea, bacteria and eukaryotes. • Mammalian prohibitins are the most studied SPFH proteins. • Prohibitin ligands exhibit anticancer, car
Highlights • The stomatin/prohibitin/flotillin/HflK/C (SPFH) domain is present in archaea, bacteria and eukaryotes. • Mammalian prohibitins are the most studied SPFH proteins. • Prohibitin ligands exhibit anticancer, car