NERNST: a genetically-encoded ratiometric non-destructive sensing tool to estimate NADP(H) redox status in bacterial, plant and animal systems

Autor: Pamela E. Molinari, Adriana R. Krapp, Andrea Weiner, Hannes M. Beyer, Arun Kumar Kondadi, Tim Blomeier, Melina López, Pilar Bustos-Sanmamed, Evelyn Tevere, Wilfried Weber, Andreas S. Reichert, Nora B. Calcaterra, Mathias Beller, Nestor Carrillo, Matias D. Zurbriggen

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)

Abstract NADP(H) is a central metabolic hub providing reducing equivalents to multiple biosynthetic, regulatory and antioxidative pathways in all living organisms. While biosensors are available to determine NADP+ or NADPH levels in vivo, no probe ex

Externí odkaz: https://doaj.org/article/b1ef3a8f51134470b32d0beb2347929b

Genetic variations in G-Quadruplex forming sequences affect the transcription of human disease-related genes

Autor: Agustín Lorenzatti, Ernesto J. Piga, Mauro Gismondi, Andrés Binolfi, Ezequiel Margarit, Nora B. Calcaterra, Pablo Armas

Guanine-rich DNA strands can fold into non-canonical four-stranded secondary structures named G-quadruplexes (G4s). G4s folded in proximal promoter regions (PPR) are associated either with positive or negative transcriptional regulation. Given that s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::518bf23dbdda6facf764963ad7ccbcbe
https://doi.org/10.1101/2022.08.16.503999

Insights into vertebrate head development: from cranial neural crest to the modelling of neurocristopathies

Autor: Gabriela Coux, Pablo Armas, Nora B. Calcaterra, Andrea M.J. Weiner

Publikováno v: The International Journal of Developmental Biology. 65:215-225

Although the vertebrate head has evolved to a wide collection of adaptive shapes, the fundamental signalling pathways and cellular events that outline the head skeleton have proven to be highly conserved. This conservation suggests that major morphol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bcad754b165a2304b8e79394bdae44b
https://doi.org/10.1387/ijdb.200229nc

Fishing the molecular bases of Treacher Collins syndrome.

Autor: Andrea M J Weiner, Nadia L Scampoli, Nora B Calcaterra

Publikováno v: PLoS ONE, Vol 7, Iss 1, p e29574 (2012)

Treacher Collins syndrome (TCS) is an autosomal dominant disorder of craniofacial development, and mutations in the TCOF1 gene are responsible for over 90% of TCS cases. The knowledge about the molecular mechanisms responsible for this syndrome is re

Externí odkaz: https://doaj.org/article/1d0f49317a0a44019fce705332045c80

Conservation of Zebrafish MicroRNA-145 and Its Role during Neural Crest Cell Development

Autor: Andrea M.J. Weiner, Tomás J. Steeman, Juan A. Rubiolo, Nora B. Calcaterra, Laura Sánchez

Publikováno v: Genes
Genes, Vol 12, Iss 1023, p 1023 (2021)
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
Volume 12
Issue 7
Minerva: Repositorio Institucional de la Universidad de Santiago de Compostela
Universidad de Santiago de Compostela (USC)
RepHipUNR (UNR)
Universidad Nacional de Rosario
instacron:UNR

The neural crest is a multipotent cell population that develops from the dorsal neural fold of vertebrate embryos in order to migrate extensively and differentiate into a variety of tissues. A number of gene regulatory networks coordinating neural cr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b106a24ecc8e124d2267615f11b3d1a0
https://doi.org/10.3390/genes12071023