Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Nora, Graf"'
Autor:
Alexander Bröhm, Tabea Schoch, Michael Dukatz, Nora Graf, Franziska Dorscht, Evelin Mantai, Sabrina Adam, Pavel Bashtrykov, Albert Jeltsch
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
DNA methyltransferase 3A (DNMT3A) is shown to efficiently methylate recombinant mononucleosome linker DNA and a role for H3K36me3 in the stimulation of DNA methylation is revealed that is independent of its interaction with the PWWP domain.
Externí odkaz:
https://doaj.org/article/85ca972b3f49401a9ad2f077df84cfcc
Autor:
Alexander, Bröhm, Tabea, Schoch, Michael, Dukatz, Nora, Graf, Franziska, Dorscht, Evelin, Mantai, Sabrina, Adam, Pavel, Bashtrykov, Albert, Jeltsch
Publikováno v:
Communications biology. 5(1)
Recently, the structure of the DNMT3A2/3B3 heterotetramer complex bound to a mononucleosome was reported. Here, we investigate DNA methylation of recombinant unmodified, H3K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d37e52d2e22e01d04db5a4f608a2ed71
https://pubmed.ncbi.nlm.nih.gov/35236925
https://pubmed.ncbi.nlm.nih.gov/35236925
Autor:
Stephen J. Lippard, Nora Graf
Publikováno v:
Prof. Lippard via Erja Kajosalo
This review provides an overview of metal-based anticancer drugs and drug candidates. In particular, we focus on metal complexes that can be activated in the reducing environment of cancer cells, thus serving as prodrugs. There are many reports of Pt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::babc674381f1854c25daba0c76323db0
https://doi.org/10.1016/j.addr.2012.01.007
https://doi.org/10.1016/j.addr.2012.01.007
Publikováno v:
PMC
Cisplatin is one of the most widely used anticancer drugs. Its side effects, however, have motivated researchers to search for equally effective analogs that are better tolerated. Selectively targeting cancer tissue is one promising strategy. For thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::803fabde04757b8319c0f166ef76d9ff
https://doi.org/10.1016/j.jinorgbio.2012.02.012
https://doi.org/10.1016/j.jinorgbio.2012.02.012
Publikováno v:
PMC
Resistance of tumor cells to platinum anticancer agents poses a major problem in cancer chemotherapy. One of the mechanisms associated with platinum-based drug resistance is the enhanced capacity of the cell to carry out nucleotide excision repair (N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::814514aacd29fac1696d1b49f51863a1
https://doi.org/10.1002/cbic.201000724
https://doi.org/10.1002/cbic.201000724
Autor:
Nora Graf, Simone Krakert, Björn Schüpbach, Wolfgang E. S. Unger, Andreas Terfort, Paul Dietrich, Thomas Gross, Andreas Lippitz
Publikováno v:
Surface and Interface Analysis. 42:1184-1187
Functionalised surfaces are of interest in many fields, e.g. in biomedicine, materials science and molecular electronics. In this study a series of self-assembled aliphatic and aromatic monolayers on gold substrates with terminal amino groups was inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8ec84cb91082ca33e609489ee035772
https://doi.org/10.1002/sia.3224
https://doi.org/10.1002/sia.3224
Autor:
Wolfgang E. S. Unger, Eda Yegen, Simone Krakert, Wilfried Weigel, Andreas Lippitz, Thomas Gross, Nora Graf, Andreas Terfort
Publikováno v:
Surface Science. 603:2849-2860
The chemical constitution of functionalized supports is an important parameter that determines their performance in a broad range of applications, e.g. for immobilization of biomolecules. Supports with amino functionalized surfaces are also often use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b6877e7c3df7fef2bab71185150a6db
https://doi.org/10.1016/j.susc.2009.07.029
https://doi.org/10.1016/j.susc.2009.07.029
Publikováno v:
Analytical and Bioanalytical Chemistry. 393:1907-1912
The chemical composition of the functional surfaces of substrates used for microarrays is one of the important parameters that determine the quality of a microarray experiment. In addition to the commonly used contact angle measurements to determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8eee33cfc1e9517e0372cb57a216d47
https://doi.org/10.1007/s00216-009-2599-x
https://doi.org/10.1007/s00216-009-2599-x
Publikováno v:
Surface and Interface Analysis. 40:180-183
It is known that aminosilanized Si wafers may be used as microarray platforms. Results of an XPS study of a cleaning applied to Si wafers prior to aminosilanization are presented and discussed. Furthermore, the results of an aminosilanization protoco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f288a1b58cbe6b3efd095fdb9cbca41f
https://doi.org/10.1002/sia.2621
https://doi.org/10.1002/sia.2621
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:4786-4788
A two-step reaction cascade is applied to the sequence-specific detection of single-stranded DNA, including analyte-triggered re-activation of apo-aldolase by its cofactor Zn2+ and catalytic conversion of a chromophore.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3159231d85408b8938ba57aafb76ba8
https://doi.org/10.1016/j.bmcl.2008.07.102
https://doi.org/10.1016/j.bmcl.2008.07.102