Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Nor Eddine, Sounni"'
Autor:
Mauriane Maja, Marie Verfaillie, Patrick Van Der Smissen, Patrick Henriet, Christophe E. Pierreux, Nor Eddine Sounni, Donatienne Tyteca
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-18 (2024)
Abstract Background Breast cancer clinical outcome relies on its intrinsic molecular subtype and mortality is almost exclusively due to metastasis, whose mechanism remains unclear. We recently revealed the specific contribution of plasma membrane cho
Externí odkaz:
https://doaj.org/article/148eabf81f0749c89915c407fde3ee39
Autor:
Gilles Rademaker, Yasmine Boumahd, Raphaël Peiffer, Sandy Anania, Tom Wissocq, Maude Liégeois, Géraldine Luis, Nor Eddine Sounni, Ferman Agirman, Naïma Maloujahmoum, Pascal De Tullio, Marc Thiry, Akeila Bellahcène, Vincent Castronovo, Olivier Peulen
Publikováno v:
Redox Biology, Vol 53, Iss , Pp 102324- (2022)
Myoferlin, an emerging oncoprotein, has been associated with a low survival in several cancer types including pancreas ductal adenocarcinoma where it controls mitochondria structure and respiratory functions. Owing to the high susceptibility of KRAS-
Externí odkaz:
https://doaj.org/article/825b81d9bde840298a5b3b5ded7cf2a2
Autor:
Géraldine Luis, Adrien Godfroid, Shin Nishiumi, Jonathan Cimino, Silvia Blacher, Erik Maquoi, Coline Wery, Alice Collignon, Rémi Longuespée, Laetitia Montero-Ruiz, Isabelle Dassoul, Naima Maloujahmoum, Charles Pottier, Gabriel Mazzucchelli, Edwin Depauw, Akeila Bellahcène, Masaru Yoshida, Agnès Noel, Nor Eddine Sounni
Publikováno v:
Redox Biology, Vol 43, Iss , Pp 102006- (2021)
Problem: Tumor recurrence is a major clinical issue that represents the principal cause of cancer-related deaths, with few targetable common pathways. Mechanisms by which residual tumors persist and progress under a continuous shift between hypoxia-r
Externí odkaz:
https://doaj.org/article/3eb5ddbabbf94bec843e6e8d4acb98c3
Autor:
Fabien Reyal, Martine Piccart, Ivan Bièche, Sergio Roman-Roman, Didier Decaudin, Marick Lae, Anne Vincent-Salomon, Agnès Noel, Nor Eddine Sounni, Pierre Foidart, Audrey Rapinat, David Gentien, Sophie Vacher, Justine Fleury, Fariba Nemati, Elodie Montaudon, Ahmed Dahmani, Franck Assayag, Ludmilla de Plater, Jean-Luc Servely, Sophie Château-Joubert, Rania El-Botty, Florence Coussy, Cécile Laurent, Elisabetta Marangoni
List of genes differentially regulated between resistant and responder PDX.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34239787458093aa4a253bb2ab2e7500
https://doi.org/10.1158/1078-0432.22470075.v1
https://doi.org/10.1158/1078-0432.22470075.v1
Autor:
Fabien Reyal, Martine Piccart, Ivan Bièche, Sergio Roman-Roman, Didier Decaudin, Marick Lae, Anne Vincent-Salomon, Agnès Noel, Nor Eddine Sounni, Pierre Foidart, Audrey Rapinat, David Gentien, Sophie Vacher, Justine Fleury, Fariba Nemati, Elodie Montaudon, Ahmed Dahmani, Franck Assayag, Ludmilla de Plater, Jean-Luc Servely, Sophie Château-Joubert, Rania El-Botty, Florence Coussy, Cécile Laurent, Elisabetta Marangoni
Purpose: Triple-negative breast cancer (TNBC) patients with residual disease after neoadjuvant chemotherapy have a poor outcome. We developed patient-derived xenografts (PDX) from residual tumors to identify efficient chemotherapies and predictive bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e973375fe05dffeef6b1cd0d284cf17
https://doi.org/10.1158/1078-0432.c.6527424
https://doi.org/10.1158/1078-0432.c.6527424
Autor:
Fabien Reyal, Martine Piccart, Ivan Bièche, Sergio Roman-Roman, Didier Decaudin, Marick Lae, Anne Vincent-Salomon, Agnès Noel, Nor Eddine Sounni, Pierre Foidart, Audrey Rapinat, David Gentien, Sophie Vacher, Justine Fleury, Fariba Nemati, Elodie Montaudon, Ahmed Dahmani, Franck Assayag, Ludmilla de Plater, Jean-Luc Servely, Sophie Château-Joubert, Rania El-Botty, Florence Coussy, Cécile Laurent, Elisabetta Marangoni
Boxplot of the expression of genes encoding proteins involved in capecitabine metabolism (TYMP, TYMS, TK1, DPYD) and cell-cycle control (RB1, CDKN2A, CCND1).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a4c2b5a7074dd9acac3071b6e5f0020
https://doi.org/10.1158/1078-0432.22470090.v1
https://doi.org/10.1158/1078-0432.22470090.v1
Autor:
Guy Jerusalem, Nor Eddine Sounni, Agnès Noël, Elisabetta Marangoni, Véronique Jossa, Michel Coibion, Joëlle Collignon, Sophie Château-Joubert, Elodie Montaudon, Erik Maquoi, Laetitia Montero-Ruiz, Mehdi Lienard, Silvia Blacher, Jean Radermacher, Cassandre Yip, Pierre Foidart
Supplemental data include a Supplemental Table-1, Supplemental Figure 1, Supplemental Figure 2, Supplemental Figure 3, Supplemental Figure 4, Supplemental Figure 5 and Supplemental Figure 6. Supplemental Table-1 is related to Figure 1 Supplemental Fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ee9372e722db3dd3ed1ee1ef5b948a2
https://doi.org/10.1158/1078-0432.22472927
https://doi.org/10.1158/1078-0432.22472927
Autor:
Guy Jerusalem, Nor Eddine Sounni, Agnès Noël, Elisabetta Marangoni, Véronique Jossa, Michel Coibion, Joëlle Collignon, Sophie Château-Joubert, Elodie Montaudon, Erik Maquoi, Laetitia Montero-Ruiz, Mehdi Lienard, Silvia Blacher, Jean Radermacher, Cassandre Yip, Pierre Foidart
Purpose:Here, we investigated the clinical relevance of an unprecedented combination of three biomarkers in triple-negative breast cancer (TNBC), both in human samples and in patient-derived xenografts of TNBC (PDX-TNBC): EGFR, its recently identifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::047c1d729f1da9d2c61a5fe29589abde
https://doi.org/10.1158/1078-0432.c.6528377
https://doi.org/10.1158/1078-0432.c.6528377
Autor:
Nor Eddine Sounni, Agnès Noel, Guy Jerusalem, Philippe Delvenne, Joelle Collignon, Erik Maquoi, Jean Michel Foidart, Didier Cataldo, Carine Munaut, Silvia Blacher, Jonathan Cimino, Cassandre Yip, Alice Truong, Alexandra Paye
MT4-MMP (MMP-17) is a glycosylphosphatidyl inositol–anchored matrix metalloprotease expressed on the surface of cancer cells that promotes tumor growth and metastasis. In this report, we identify MT4-MMP as an important driver of cancer cell prolif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42bf5bcf935066883f41386edafe6196
https://doi.org/10.1158/0008-5472.c.6505668
https://doi.org/10.1158/0008-5472.c.6505668
Autor:
Nor Eddine Sounni, Agnès Noel, Guy Jerusalem, Philippe Delvenne, Joelle Collignon, Erik Maquoi, Jean Michel Foidart, Didier Cataldo, Carine Munaut, Silvia Blacher, Jonathan Cimino, Cassandre Yip, Alice Truong, Alexandra Paye
Supplemental data files 2 figures including figure S1 related to figure 4 and Figure S2 related to Figure 5 and Figure 6 and detailed supplemental experimental procedures for methods referred in material and method section including RT-PCR analysis a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::065916e73d9be0fadc5d6a046aafbce0
https://doi.org/10.1158/0008-5472.22400769.v1
https://doi.org/10.1158/0008-5472.22400769.v1