Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Nooruddin Khan"'
Autor:
Md Mehedi Hossain, Arfan Khalid, Zaheen Akhter, Sabra Parveen, Mir Owais Ayaz, Aadil Qadir Bhat, Neetu Badesra, Farheen Showket, Mohmmad Saleem Dar, Farhan Ahmed, Sumit Dhiman, Mukesh Kumar, Umed Singh, Razak Hussain, Pankaj Keshari, Ghulam Mustafa, Amit Nargorta, Neha Taneja, Somesh Gupta, Riyaz A. Mir, Aravind Singh Kshatri, Utpal Nandi, Nooruddin Khan, P. Ramajayan, Govind Yadav, Zabeer Ahmed, Parvinder Pal Singh, Mohd Jamal Dar
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract JAK-STAT signalling pathway inhibitors have emerged as promising therapeutic agents for the treatment of hair loss. Among different JAK isoforms, JAK3 has become an ideal target for drug discovery because it only regulates a narrow spectrum
Externí odkaz:
https://doaj.org/article/64faa3ccd8d24a228b59d9fca5872f55
Autor:
Vengala Rao Yenuganti, Sumbul Afroz, Rafiq Ahmad Khan, Chandrima Bharadwaj, Deepti Kailash Nabariya, Nagaraj Nayak, Madhuri Subbiah, Kumaraswami Chintala, Sharmistha Banerjee, Pallu Reddanna, Nooruddin Khan
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-15 (2022)
Abstract Background Exosomes are nano-sized vesicles secreted by various cells into the intra and extracellular space and hence is an integral part of biological fluids including milk. In the last few decades, many research groups have proved the pot
Externí odkaz:
https://doaj.org/article/8726ac4786144ff2bbc1f6c5eecada42
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Nutrient sensor GCN2 plays a crucial role in the maintenance of cellular homeostasis during the condition of amino acid deprivation. Dysfunction in the GCN2 signaling underlies several chronic metabolic diseases. Recent studies highlight the anti-vir
Externí odkaz:
https://doaj.org/article/888b4244ec684bf0a08333d1b35acaa6
Autor:
Srikanth Battu, Sumbul Afroz, Jeevan Giddaluru, Saima Naz, Weishan Huang, Saratchandra Singh Khumukcham, Rafiq Ahmad Khan, Saleem Yousuf Bhat, Insaf Ahmed Qureshi, Bramanandam Manavathi, Aleem Ahmed Khan, Avery August, Seyed Ehtesham Hasnain, Nooruddin Khan
Publikováno v:
PLoS Biology, Vol 16, Iss 4, p e2005317 (2018)
Activation of the amino acid starvation response (AAR) increases lifespan and acute stress resistance as well as regulates inflammation. However, the underlying mechanisms remain unclear. Here, we show that activation of AAR pharmacologically by Halo
Externí odkaz:
https://doaj.org/article/4475e910e3734fa4a2d29e1cbe9801cb
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Metabolic adaptation to the changing nutrient levels in the cellular microenvironment plays a decisive role in the maintenance of homeostasis. Eukaryotic cells are equipped with nutrient sensors, which sense the fluctuating nutrients levels and accor
Externí odkaz:
https://doaj.org/article/4836b7feadfc4dc595005384f53430bb
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Ischemia-reperfusion injury is a well-known pathological hallmark associated with diabetic retinopathy, glaucoma and other related retinopathies that ultimately can lead to visual impairment and vision loss. Retinal ischemia pathogenesis involves a c
Externí odkaz:
https://doaj.org/article/d63fbba1fd614e7d913f4f6f8971f0de
Autor:
Shuzhao Li, Youngja Park, Sai Duraisingham, Frederick H Strobel, Nooruddin Khan, Quinlyn A Soltow, Dean P Jones, Bali Pulendran
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 7, p e1003123 (2013)
The functional interpretation of high throughput metabolomics by mass spectrometry is hindered by the identification of metabolites, a tedious and challenging task. We present a set of computational algorithms which, by leveraging the collective powe
Externí odkaz:
https://doaj.org/article/c57501b2771d4ce494384c53719163f1
Autor:
Kala Jyothi Kanaparthi, Sumbul Afroz, Gillipsie Minhas, Anurupa Moitra, Rafiq Ahmad Khan, Jayashankar Medikonda, Saima Naz, Sai Nikhith Cholleti, Sharmistha Banerjee, Nooruddin Khan
Publikováno v:
Immunology Letters. 242:27-36
Mycobacterium tuberculosis (M.tb) is a multifaceted bacterial pathogen known to infect more than 2 billion people globally. However, a majority of the individuals (90%) show no overt clinical symptoms of active Tuberculosis (TB) and, it is reported t
Autor:
Harshavardhan Bhuktar, Sharda Shukla, Kumar Reddy Kakularam, Srikanth Battu, Manupati Srikanth, Susmita Srivastava, Raghavender Medishetti, Pooja Ram, P.C. Jagadish, Mahaboobkhan Rasool, Sandipan Chakraborty, Nooruddin Khan, Pallu Reddanna, Srinivas Oruganti, Manojit Pal
Publikováno v:
Bioorganic Chemistry. 138:106606
Publikováno v:
Biomaterials science. 10(11)
Dengue is a mosquito-borne disease caused by the four serotypes of the dengue virus (DENV 1-4). It is growing at an alarming rate globally, which could be partly attributed to the lack of an effective therapeutic regimen. Therefore, strategies for de