Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Noortje M. van Maarseveen"'
Autor:
Sandra Witteveen, Antoni P. A. Hendrickx, Angela de Haan, Daan W. Notermans, Fabian Landman, Marga G. van Santen-Verheuvel, Sabine C. de Greeff, Ed J. Kuijper, Noortje M. van Maarseveen, Saara Vainio, Leo M. Schouls
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT Staphylococcus argenteus is a recently described member of the Staphylococcus aureus complex (SAC) and is associated with human disease. The frequency and intensity of infections caused by S. argenteus are similar to those of Staphylococcus
Externí odkaz:
https://doaj.org/article/6ea3970304fc4251b5c4cf41744ba18a
Autor:
Monique Nijhuis, Noortje M van Maarseveen, Stephane Lastere, Pauline Schipper, Eoin Coakley, Bärbel Glass, Mirka Rovenska, Dorien de Jong, Colombe Chappey, Irma W Goedegebuure, Gabrielle Heilek-Snyder, Dominic Dulude, Nick Cammack, Lea Brakier-Gingras, Jan Konvalinka, Neil Parkin, Hans-Georg Kräusslich, Francoise Brun-Vezinet, Charles A B Boucher
Publikováno v:
PLoS Medicine, Vol 4, Iss 1, p e36 (2007)
BACKGROUND: HIV protease inhibitor (PI) therapy results in the rapid selection of drug resistant viral variants harbouring one or two substitutions in the viral protease. To combat PI resistance development, two approaches have been developed. The fi
Externí odkaz:
https://doaj.org/article/9b249d2a4df84827a9f40807268dca47
Autor:
Ton Van Zwet, Brenda Slotboom, Noortje M Van Maarseveen, Hanneke Berkhout, Johannes G Kusters, Edwin C. H. Boel, Sebastian van Marm, Jeroen H.B. van de Bovenkamp, Laura Van Dommelen, Joyce F Braam, Ferry Hagen, Tim T Severs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed159a4bd19b7504e2d453e33dfe6781
https://dspace.library.uu.nl/handle/1874/349473
https://dspace.library.uu.nl/handle/1874/349473
Autor:
Jan Konvalinka, Tomáš Cihlář, Dorien de Jong, Kirsten M. Stray, Jiří Brynda, Noortje M van Maarseveen, Milan Kožíšek, Pavlína Řezáčová, Monique Nijhuis, Klára Grantz Šašková
Publikováno v:
Journal of Virology. 88:3586-3590
Insertions in the protease (PR) region of human immunodeficiency virus (HIV) represent an interesting mechanism of antiviral resistance against HIV PR inhibitors (PIs). Here, we demonstrate the improved ability of a phosphonate-containing experimenta
Autor:
Andy I. M. Hoepelman, Dorien de Jong, Noortje M van Maarseveen, Greg L. Beilhartz, Raymond F. Schinazi, Annemarie M. J. Wensing, Joop E. Arends, Aleksandr Obikhod, Matthias Götte, Monique Nijhuis, Sijia Tao, Marieke Pingen
Publikováno v:
Antivir Ther
Background HIV–HBV-coinfected individuals who need to be treated only for their HBV infection have limited therapeutic options, since most approved anti-HBV agents have a risk of selecting for drug-resistant HIV mutants. In vivo data are inconclusi
Publikováno v:
Current Opinion in HIV and AIDS. 3:627-632
Several alternative mechanisms that cause protease inhibitor resistance have been proposed. A summary of the proposed mechanisms and the status regarding their clinical relevance is given.At this moment only changes in the cleavage sites of protease
Autor:
Milan Kozisek, Jiri Brynda, Ron M. Kagan, Charles A. Boucher, Jan Konvalinka, Pavlina Rezacova, Noortje M van Maarseveen, Dorien de Jong, Klára Grantz Šašková, Monique Nijhuis
Publikováno v:
Journal of Virology. 82:5869-5878
While the selection of amino acid insertions in human immunodeficiency virus (HIV) reverse transcriptase (RT) is a known mechanism of resistance against RT inhibitors, very few reports on the selection of insertions in the protease (PR) coding region
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 42:162-168
Little is known about the factors which drive the evolution of protease inhibitor-resistant human immunodeficiency virus type-1 in the absence of drugs. To examine if viral replicative capacity (RC) is an important determinant, we performed in vitro
Autor:
Dorien de Jong, Monique Nijhuis, Axel Fun, Dan I. Andersson, Noortje M van Maarseveen, Pauline J. Schipper, Martin Lepšík, Charles A. Boucher
Publikováno v:
Retrovirology
Retrovirology, Vol 9, Iss 1, p 29 (2012)
Retrovirology, 9. BioMed Central Ltd.
Retrovirology, Vol 9, Iss 1, p 29 (2012)
Retrovirology, 9. BioMed Central Ltd.
Background Mutations in the substrate of HIV-1 protease, especially changes in the NC/p1 cleavage site, can directly contribute to protease inhibitor (PI) resistance and also compensate for defects in viral replicative capacity (RC) due to a drug res
Autor:
Axel Fun, Noortje M van Maarseveen, Renee Maas, Monique Nijhuis, Jana Pokorná, Pauline J. Schipper, Jan Konvalinka
Publikováno v:
Retrovirology, Vol 8, Iss 1, p 70 (2011)
Retrovirology
Retrovirology
Background Maturation inhibitors are an experimental class of antiretrovirals that inhibit Human Immunodeficiency Virus (HIV) particle maturation, the structural rearrangement required to form infectious virus particles. This rearrangement is trigger