Výsledky vyhledávání - "Noorhaan Abouomar"

Estimated Binding Energies of Drug-Like and Nondrug-Like Molecules in the Active Site of HIV-1 Integrase, 1BIS.pdb, and Two Mutant Models: Y143R and N155H

Autor: Sarah Ramzy, Matthew Mekolochik, Christopher Shannon, Liliana Nassar, Julie B. Ealy, Noorhaan Abouomar, Paolo Flauta, Habib Yazgi, Justin W. Cogan

Publikováno v: Advances in Bioscience and Biotechnology. :163-183

Lipinski’s “Rule of Five” was introduced for predicting oral bioavailability to describe drug-like molecules. For the purpose of this research the rules were used to separate potential inhibitors of HIV-1 integrase (1BIS.pdb) into two groups: d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::31bde18757f84e063f37ec535269c655
https://doi.org/10.4236/abb.2017.85013

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