Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Noorafza Q. Khan"'
Autor:
Madeeha H. Sheikh, Mariella Errede, Antonio d'Amati, Noorafza Q. Khan, Silvia Fanti, Rodrigo A. Loiola, Simon McArthur, Gareth S. D. Purvis, Caroline E. O'Riordan, Davide Ferorelli, Alessandro Dell'Erba, Julius Kieswich, Chis Reutelingsperger, Eugenio Maiorano, Magdi Yaqoob, Christoph Thiemermann, Andrea Baragetti, Alberico Luigi Catapano, Giuseppe Danilo Norata, Federica Marelli‐Berg, Daniela Virgintino, Egle Solito
Publikováno v:
Faseb Journal, 36(1):e22107. FASEB
Mounting evidence has linked the metabolic disease to neurovascular disorders and cognitive decline. Using a murine model of a high-fat high-sugar diet mimicking obesity-induced type 2 diabetes mellitus (T2DM) in humans, we show that pro-inflammatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99949b11087c1cd9c4fcac0b45dfc8b7
https://pubmed.ncbi.nlm.nih.gov/34939700
https://pubmed.ncbi.nlm.nih.gov/34939700
Autor:
Binta Patel, Sukhjit K. Dhariwal, Noorafza Q. Khan, Farihah Husain, Elizabeth G. Wood, Roger Corder, Mark R. Pothecary, Shahbaz S. Kang
Publikováno v:
Tetrahedron. 71:3059-3065
The effects of oligomeric procyanidins (OPC) on vascular endothelial function provide a plausible explanation for the reduced incidence of coronary heart disease in red wine drinkers. Grape variety is an important influence on the amounts of OPC in w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0ee2bdf56a3d6b48929097dea3065b8
https://doi.org/10.1016/j.tet.2014.10.078
https://doi.org/10.1016/j.tet.2014.10.078
Autor:
Mark R. Pothecary, Gurvinder Rull, Roger Corder, Elizabeth G. Wood, Tomomasa Kanda, Toshihiko Shoji, Delphine M. Lees, Paul W. Caton, Noorafza Q. Khan
Publikováno v:
Journal of Agricultural and Food Chemistry. 58:4008-4013
Flavonoid-rich diets are associated with a lower mortality from cardiovascular disease. This has been linked to improvements in endothelial function. However, the specific flavonoids, or biologically active metabolites, conferring these beneficial ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cbab54755f4bbb11afa475dca0d276b
https://doi.org/10.1021/jf9031876
https://doi.org/10.1021/jf9031876
Autor:
Elizabeth G. Wood, Rodney De Palma, Imelda Sotto, Jane Butler, Martin T. Rothman, Noorafza Q. Khan, Atholl Johnston, Roger Corder
Publikováno v:
ESC Heart Failure
Aims Poor prognosis in chronic heart failure (HF) is linked to endothelial dysfunction for which there is no specific treatment currently available. Previous studies have shown reproducible improvements in endothelial function with cocoa flavanols, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5104b28fc268d4ef574576f5df5e0df
https://pubmed.ncbi.nlm.nih.gov/27588209
https://pubmed.ncbi.nlm.nih.gov/27588209
Publikováno v:
Molecular Pharmacology. 59:163-169
Endothelin-1 (ET-1) is secreted from endothelial and vascular smooth muscle cells (VSMC) after intracellular hydrolysis of big ET-1 by endothelin converting enzyme (ECE). The metallopeptidase called ECE-1 is widely thought to be the physiological ECE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7684ffb8825dc721cdda196de14776c5
https://doi.org/10.1124/mol.59.2.163
https://doi.org/10.1124/mol.59.2.163
Publikováno v:
Biochemical and Biophysical Research Communications. 207:355-362
Subcellular fractionation of the phosphoramidon sensitive membrane-bound endothelin converting enzyme (ECE-1) activity from homogenates of bovine aortic endothelial cells and the human endothelial cell line EA.hy 926, combined with studies of intact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c20cb702bf493eb6afff3c1ac954a0
https://doi.org/10.1006/bbrc.1995.1195
https://doi.org/10.1006/bbrc.1995.1195
Publikováno v:
The Journal of endocrinology. 208(3)
Consumption of a fructose-rich diet leads to insulin resistance and dyslipidemia in part due to elevated gluconeogenesis and lipogenesis. SIRT1, an NAD(+)-dependent protein deacetylase, can induce gluconeogenesis and lipogenesis. The aim of this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f53cac0c2f0801f4742168c82c3e058
https://pubmed.ncbi.nlm.nih.gov/21212096
https://pubmed.ncbi.nlm.nih.gov/21212096
Publikováno v:
Journal of Cardiovascular Pharmacology. 22:S73-S76
Several studies have shown that phosphoramidon (PHOS) reduces the release of endothelin-1 (ET-1) from cultured endothelial cells. Moreover, the main endothelin-converting enzyme (ECE) activity in these cells is a membrane-bound metallopeptidase that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11459dba5f824e8293acfc3b8a2aef17
https://doi.org/10.1097/00005344-199322008-00021
https://doi.org/10.1097/00005344-199322008-00021
Publikováno v:
Clinical science (London, England : 1979). 103
Regular consumption of red wine reduces mortality from coronary heart disease. This observation has been attributed to the anti-thrombotic effects of ethanol and to the antioxidant properties of polyphenolic compounds present in red wine. Here we sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4df5d90a38370c783b28e70cdc90309
https://pubmed.ncbi.nlm.nih.gov/12193058
https://pubmed.ncbi.nlm.nih.gov/12193058
Publikováno v:
Journal of cardiovascular pharmacology. 31
Endothelin-1 (ET-1) is synthesized by a number of cell types. including endothelial, epithelial, and smooth muscle cells. Initial biosynthesis occurs as a protein precursor, preproendothelin-1 (preproET-1). This is processed intracellularly to the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::110f5a0dbc5d4f00813abfac0a7330cc
https://pubmed.ncbi.nlm.nih.gov/9595396
https://pubmed.ncbi.nlm.nih.gov/9595396