Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Noor Shakfa"'
Autor:
David P. Cook, Kristianne J. C. Galpin, Galaxia M. Rodriguez, Noor Shakfa, Juliette Wilson-Sanchez, Maryam Echaibi, Madison Pereira, Kathy Matuszewska, Jacob Haagsma, Humaira Murshed, Alison O. Cudmore, Elizabeth MacDonald, Alicia Tone, Trevor G. Shepherd, James J. Petrik, Madhuri Koti, Barbara C. Vanderhyden
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Ovarian cancers exhibit high rates of recurrence and poor treatment response. Preclinical models that recapitulate human disease are critical to develop new therapeutic approaches. Syngeneic mouse models allow for the generation of tumours c
Externí odkaz:
https://doaj.org/article/f661987fb8f3474ebc28deb27ada3401
Autor:
Madhuri Koti, Stephen Chenard, Ali Hamade, Noor Shakfa, Deyang Li, Gwenaelle Conseil, Elizabeth D Lightbody, Juliette Wilson-Sanchez, Natasha A. Jawa, Brian J. Laight, Afrakoma Afriyie-Asante, Kathrin Tyryshkin, Martin Koebel
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 4 (2023)
Background High-grade serous ovarian carcinoma (HGSC) is the most lethal gynecologic malignancy characterized by resistance to chemotherapy and high rates of recurrence. HGSC tumors display a high prevalence of tumor suppressor gene loss. Given the t
Externí odkaz:
https://doaj.org/article/efaa5a34fcf548638e10eaee0c1e7c15
Autor:
David P Cook, Kristianne JC Galpin, Galaxia M Rodriguez, Noor Shakfa, Juliette Wilson-Sanchez, Madison Pereira, Kathy Matuszewska, Jacob Haagsma, Humaira Murshed, Alison O Cudmore, Elizabeth MacDonald, Alicia Tone, Trevor G. Shepherd, James J Petrik, Madhuri Koti, Barbara C. Vanderhyden
Ovarian cancers often exhibit high rates of recurrence and poor treatment response. Preclinical models that recapitulate the heterogeneity of human disease are critical to develop new therapeutic approaches. While patient-derived models are a powerfu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb4d182275bf3f831ba2a3e5c46ad13b
https://doi.org/10.1101/2023.03.09.531888
https://doi.org/10.1101/2023.03.09.531888
Publikováno v:
Br J Cancer
Ovarian cancer is the leading cause of mortality due to gynecologic malignancy. The majority of women diagnosed with the most common subtype, high-grade serous ovarian carcinoma (HGSC), develop resistance to conventional therapies despite initial res
Autor:
Noor Shakfa, Deyang Li, Gwenaëlle Conseil, Elizabeth Lightbody, Juliette Wilson-Sanchez, Ali Hamade, Stephen Chenard, Brian Laight, Afrakoma Afriyie-Asante, Kathrin Tyryshkin, Martin Köbel, Madhuri Koti
BackgroundHigh grade serous ovarian carcinoma (HGSC) is the most lethal gynecologic malignancy characterized by chemoresistance and high rates of recurrence. HGSC tumors display a high prevalence of tumor suppressor gene loss. Loss of BRCA1 and PTEN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cd404322f45b591f1f7cfbee0f08829
https://doi.org/10.1101/2022.06.27.497846
https://doi.org/10.1101/2022.06.27.497846
Autor:
Noor Shakfa, Deyang Li, Gwenaelle Conseil, Elizabeth D Lightbody, Juliette Wilson-Sanchez, Ali Hamade, Stephen Chenard, Natasha A. Jawa, Brian J. Laight, Afrakoma Afriyie-Asante, Kathrin Tyryshkin, Martin Koebel, Madhuri Koti
Publikováno v:
Journal for ImmunoTherapy of Cancer. 11:e006170
BackgroundHigh-grade serous ovarian carcinoma (HGSC) is the most lethal gynecologic malignancy characterized by resistance to chemotherapy and high rates of recurrence. HGSC tumors display a high prevalence of tumor suppressor gene loss. Given the ty
Autor:
Afrakoma Afriyie-Asante, Palak G. Patel, Madhuri Koti, Eun Young Kang, Rachel Sue-A-Quan, May Phyo Nyi Nyi, Noor Shakfa, Martin Köbel
Publikováno v:
Gynecologic oncology. 162(2)
Objective To define the pre-treatment tumour immune landscape of clear cell carcinoma of the ovary (CCOC). Methods We investigated the infiltration profiles of selected immune cell populations and immune checkpoint proteins that have been previously
Publikováno v:
Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance ISBN: 9780128213100
Immunogenic cell death (ICD) is an immune priming form of cell death that occurs following exposure to physical or microbial insults. Unlike apoptosis, ICD events trigger the release of damage-associated molecular patterns (DAMPs) that facilitate a v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bf299491250eeb0d6ef771601d21284
https://doi.org/10.1016/b978-0-12-821310-0.00008-5
https://doi.org/10.1016/b978-0-12-821310-0.00008-5
Autor:
Deborah H. Anderson, David N. Brindley, Artem Cherkasov, Mackenzie L. Coatham, E. Dadachova, Shoukat Dedhar, Vincenzo Giambra, Juha P. Himanen, Michael Jewer, Madhuri Koti, Nathan A. Lack, Xueqing Lun, Paul C. McDonald, Jennifer M. Nagel, Dimitar B. Nikolov, Alisha Poole, Lynne-Marie Postovit, Afshin Raouf, Stephen M. Robbins, Hilal Saraç, Donna L. Senger, Noor Shakfa, Peter M. Siegel, D. Robert Siemens, Francesco Tamiro, Josie Ursini-Siegel, Andrew P. Weng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05037e925fddfa0d06394838a5c405b2
https://doi.org/10.1016/b978-0-12-821310-0.09987-3
https://doi.org/10.1016/b978-0-12-821310-0.09987-3
Autor:
Noor Shakfa, Deyang Li, Ali Hamade, Gwenaëlle Conseil, Elizabeth Lightbody, Afrakoma Afriyie-Asante, Stephen Chenard, Juliette Wilson-Sanchez, Madhuri Koti
Publikováno v:
Cancer Research. 81:1708-1708
High grade serous ovarian carcinoma (HGSC) is the most lethal gynecologic malignancy with high rates of chemotherapy resistance and poor outcomes. Our previous studies have demonstrated the variable tumor immune microenvironment states that associate