Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Noor Hazim Bin Sulaimee"'
Autor:
Charlene Priscilla Poore, Jeyapriya R. Sundaram, Sashi Kesavapany, Wei Fun Cheong, Sally A. Frautschy, Tej K. Pareek, Markus R. Wenk, Noor Hazim Bin Sulaimee, Harish C. Pant, Chian-Ming Low
Publikováno v:
J Alzheimers Dis
Several studies have indicated that neuroinflammation is indeed associated with neurodegenerative disease pathology. However, failures of recent clinical trials of anti-inflammatory agents in neurodegenerative disorders have emphasized the need to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c10ce372432d65f0676ac627c1fb80
https://europepmc.org/articles/PMC8092919/
https://europepmc.org/articles/PMC8092919/
Autor:
Gavin S. Dawe, Wei Fun Cheong, A.B.M.A. Asad, Harish C. Pant, Sashi Kesavapany, Charlene Priscilla Poore, Markus R Wenk, Noor Hazim Bin Sulaimee, Jeyapriya R. Sundaram, Tej K. Pareek, Ramamoorthy Rajkumar, Kai-Hsiang Chuang
Publikováno v:
The Journal of Neuroscience. 33:334-343
The aberrant hyperactivation of Cyclin-dependent kinase 5 (Cdk5), by the production of its truncated activator p25, results in the formation of hyperphosphorylated tau, neuroinflammation, amyloid deposition, and neuronal deathin vitroandin vivo. Mech