Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Noor Diab"'
Autor:
Sara Moufarrij, Aneil Srivastava, Stephanie Gomez, Melissa Hadley, Erica Palmer, Paul Tran Austin, Sarah Chisholm, Noor Diab, Kyle Roche, Angela Yu, Jing Li, Wenge Zhu, Micael Lopez-Acevedo, Alejandro Villagra, Katherine B. Chiappinelli
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/b7abc25700cf4e8dbe1b7d6521f0846e
Autor:
Katherine B. Chiappinelli, Stephen B. Baylin, Ting Wang, Reiner Strick, Pamela L. Strissel, Xiaoyun Xing, Michael J. Topper, Olivia Cox, Erin E. Grundy, Angela Yu, Stephanie Gomez, Uzma Rentia, Tomas Kanholm, Melissa Hadley, Elisa Arthofer, Noor Diab, James I. McDonald
Supplementary Table from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a TP53-Dependent Manner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::818ab8fad5d90b63257bf5c83608134d
https://doi.org/10.1158/0008-5472.22429779
https://doi.org/10.1158/0008-5472.22429779
Autor:
Katherine B. Chiappinelli, Stephen B. Baylin, Ting Wang, Reiner Strick, Pamela L. Strissel, Xiaoyun Xing, Michael J. Topper, Olivia Cox, Erin E. Grundy, Angela Yu, Stephanie Gomez, Uzma Rentia, Tomas Kanholm, Melissa Hadley, Elisa Arthofer, Noor Diab, James I. McDonald
Epithelial ovarian carcinomas are particularly deadly due to intratumoral heterogeneity, resistance to standard-of-care therapies, and poor response to alternative treatments such as immunotherapy. Targeting the ovarian carcinoma epigenome with DNA m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d898d23e497f1395dbbac63ffe031166
https://doi.org/10.1158/0008-5472.c.6513453.v1
https://doi.org/10.1158/0008-5472.c.6513453.v1
Autor:
Katherine B. Chiappinelli, Stephen B. Baylin, Ting Wang, Reiner Strick, Pamela L. Strissel, Xiaoyun Xing, Michael J. Topper, Olivia Cox, Erin E. Grundy, Angela Yu, Stephanie Gomez, Uzma Rentia, Tomas Kanholm, Melissa Hadley, Elisa Arthofer, Noor Diab, James I. McDonald
Supplementary Figure from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a TP53-Dependent Manner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24e34a195a2aed3778aaabda60767c09
https://doi.org/10.1158/0008-5472.22429785.v1
https://doi.org/10.1158/0008-5472.22429785.v1
Autor:
Katherine B. Chiappinelli, Stephen B. Baylin, Ting Wang, Reiner Strick, Pamela L. Strissel, Xiaoyun Xing, Michael J. Topper, Olivia Cox, Erin E. Grundy, Angela Yu, Stephanie Gomez, Uzma Rentia, Tomas Kanholm, Melissa Hadley, Elisa Arthofer, Noor Diab, James I. McDonald
Supplementary Data from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a TP53-Dependent Manner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b6cac7a09216980d7200774c50a439
https://doi.org/10.1158/0008-5472.22429788.v1
https://doi.org/10.1158/0008-5472.22429788.v1
Autor:
Tomas Kanholm, Melissa Hadley, Reiner Strick, Erin E. Grundy, Ting Wang, Pamela L. Strissel, Stephanie Gomez, Angela Yu, Uzma Rentia, Noor Diab, Michael J. Topper, Stephen B. Baylin, James I. McDonald, Xiaoyun Xing, Katherine B. Chiappinelli, Olivia Cox, Elisa Arthofer
Publikováno v:
Cancer Research. 81:5176-5189
Epithelial ovarian carcinomas are particularly deadly due to intratumoral heterogeneity, resistance to standard-of-care therapies, and poor response to alternative treatments such as immunotherapy. Targeting the ovarian carcinoma epigenome with DNA m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff92c7a02b46f22144ea83787cf5a312
https://doi.org/10.1158/0008-5472.can-20-4243
https://doi.org/10.1158/0008-5472.can-20-4243
Publikováno v:
The FEBS Journal. 289:1160-1179
Approximately 45% of the human genome is composed of transposable elements (TEs). Expression of these elements is tightly regulated during normal development. TEs may be expressed at high levels in embryonic stem cells but are epigenetically silenced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49ae07eb93869dc463f8fef4909dbb58
https://doi.org/10.1111/febs.15722
https://doi.org/10.1111/febs.15722
Autor:
Sara Moufarrij, Aneil Srivastava, Stephanie Gomez, Melissa Hadley, Erica Palmer, Paul Tran Austin, Sarah Chisholm, Noor Diab, Kyle Roche, Angela Yu, Jing Li, Wenge Zhu, Micael Lopez-Acevedo, Alejandro Villagra, Katherine B. Chiappinelli
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Novel therapies are urgently needed for ovarian cancer, the deadliest gynecologic malignancy. Ovarian cancer has thus far been refractory to immunotherapies that stimulate the host immune system to recognize and kill cancer cells. This may be because
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60e9746ab9e0d6cc35e0546105f2cd1e
http://link.springer.com/article/10.1038/s41598-020-60409-4
http://link.springer.com/article/10.1038/s41598-020-60409-4
Autor:
Stephanie Gomez, Olivia L Cox, Reddick R Walker, Uzma Rentia, Melissa Hadley, Elisa Arthofer, Noor Diab, Erin E Grundy, Tomas Kanholm, James I McDonald, Julie Kobyra, Erica Palmer, Satish Noonepalle, Alejandro Villagra, David Leitenberg, Catherine M Bollard, Yogen Saunthararajah, Katherine B Chiappinelli
Publikováno v:
Journal for ImmunoTherapy of Cancer. 10:e004974
BackgroundNovel therapies are urgently needed for ovarian cancer (OC), the fifth deadliest cancer in women. Preclinical work has shown that DNA methyltransferase inhibitors (DNMTis) can reverse the immunosuppressive tumor microenvironment in OC. Inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c8cc2a9f87f7c2a807e61e705834c0
https://doi.org/10.1136/jitc-2022-004974
https://doi.org/10.1136/jitc-2022-004974
Autor:
James I, McDonald, Noor, Diab, Elisa, Arthofer, Melissa, Hadley, Tomas, Kanholm, Uzma, Rentia, Stephanie, Gomez, Angela, Yu, Erin E, Grundy, Olivia, Cox, Michael J, Topper, Xiaoyun, Xing, Pamela L, Strissel, Reiner, Strick, Ting, Wang, Stephen B, Baylin, Katherine B, Chiappinelli
Publikováno v:
Cancer Res
Epithelial ovarian carcinomas (OC) are particularly deadly due to intratumoral heterogeneity, resistance to standard-of-care therapies, and poor response to alternative treatments such as immunotherapy. Targeting the OC epigenome with DNA methyltrans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::beef336a5a66145b7d9cc58c753fec7b
https://pubmed.ncbi.nlm.nih.gov/34433584
https://pubmed.ncbi.nlm.nih.gov/34433584