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pro vyhledávání: '"Noor A S, Ismail"'
Autor:
Tanya T. Cheung, Noor A. S. Ismail, Rachel Moir, Nikhil Arora, Fiona J. McDonald, Steven B. Condliffe
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
The epithelial Na+ channel (ENaC) provides for Na+ absorption in various types of epithelia including the kidney, lung, and colon where ENaC is localized to the apical membrane to enable Na+ entry into the cell. The degree of Na+ entry via ENaC large
Externí odkaz:
https://doaj.org/article/310b30e61e364527a764899b5a271d06
Publikováno v:
European Journal of Pharmacology
Neural precursor cell expressed, developmentally down-regulated protein 4-2 (Nedd4-2) mediates the internalisation / degradation of epithelial Na(+) channel subunits (α-, β- and γ-ENaC). Serum / glucocorticoid inducible kinase 1 (SGK1) and protein
Autor:
Gordon B, Watt, Noor A S, Ismail, Agustin Garcia, Caballero, Stephen C, Land, Stuart M, Wilson
Publikováno v:
British journal of pharmacology. 166(4)
Glucocorticoids appear to control Na⁺ absorption in pulmonary epithelial cells via a mechanism dependent upon serum and glucocorticoid-inducible kinase 1 (SGK1), a kinase that allows control over the surface abundance of epithelial Na⁺ channel su