Mechanism of proton transfer in class A β-lactamase catalysis and inhibition by avibactam

Autor: Pemberton, Orville A., Noor, Radwan E., M.V., Vasantha Kumar, Sanishvili, Ruslan, Kemp, M. Trent, Kearns, Fiona L., Woodcock, H. Lee, Gelis, Ioannis, Chen, Yu

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2020 Mar . 117(11), 5818-5825.

Externí odkaz: https://www.jstor.org/stable/26929342

Staphylococcus aureus FtsZ and PBP4 bind to the conformationally dynamic N-terminal domain of GpsB.

Autor: Sacco MD; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, United States., Hammond LR; Department of Molecular Biosciences, University of South Florida, Tampa, United States., Noor RE; Department of Chemistry, University of South Florida, Tampa, United States., Bhattacharya D; Department of Molecular Biosciences, University of South Florida, Tampa, United States., McKnight LJ; Department of Molecular Biosciences, University of South Florida, Tampa, United States., Madsen JJ; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, United States.; Global and Planetary Health, College of Public Health, University of South Florida, Tampa, United States., Zhang X; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, United States., Butler SG; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, United States., Kemp MT; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, United States., Jaskolka-Brown AC; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, United States., Khan SJ; Department of Molecular Biosciences, University of South Florida, Tampa, United States., Gelis I; Department of Chemistry, University of South Florida, Tampa, United States., Eswara P; Department of Molecular Biosciences, University of South Florida, Tampa, United States., Chen Y; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, United States.

Publikováno v: ELife [Elife] 2024 Apr 19; Vol. 13. Date of Electronic Publication: 2024 Apr 19.