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pro vyhledávání: '"Noon, T. Angela"'
Publikováno v:
Acta medica Nagasakiensia. 53:13-17
Eukaryotic chromatin is segregated into highly condensed heterochromatin and comparably relaxed euchromatin. Although heterochromatic gene expression is either transiently or permanently impeded, the integrity of heterochromatic DNA is critical for c
Autor:
Shibata, Atsushi, Barton, Olivia, Noon, T. Angela, Dahm, Kirsten, Deckbar, Dorothee, Goodarzi, A. Aaron, Lobrich, Markus, Jeggo, A. Penny
Publikováno v:
Acta medica Nagasakiensia. 53:19-21
The G2/M checkpoint is important in preventing cells with unrepaired DNA double strand breaks (DSBs) entering mitosis, an event which is likely to result in genomic instability. We recently reported that checkpoint arrest is maintained until close to