Zobrazeno 1 - 10
of 549
pro vyhledávání: '"Nonribosomal peptides"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 3050-3060 (2024)
Bioactivity-guided fractionation (BGF) has historically been a fruitful natural product discovery workflow. However, it is plagued by increasing rediscovery rates in recent years and new methods capable of exploring the natural product chemical space
Externí odkaz:
https://doaj.org/article/22fc55a06f2e4c57be75105267350066
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 56, Pp 825-832 (2024)
Biological control of pests and pathogens has attracted much attention due to its green, safe and effective characteristics. However, it faces the dilemma of insignificant effects in large-scale applications. Therefore, an in-depth exploration of the
Externí odkaz:
https://doaj.org/article/ca89b9f5da54400b8c1c3dc2b772480b
Autor:
J. Gerardo Hernández Delgado, Miguel G. Acedos, Fernando de la Calle, Pilar Rodríguez, José Luis García, Beatriz Galán
Publikováno v:
Marine Drugs, Vol 22, Iss 9, p 418 (2024)
Pseudomonas poae PMA22 produces safracins, a family of compounds with potent broad-spectrum anti-bacterial and anti-tumor activities. The safracins’ biosynthetic gene cluster (BGC sac) consists of 11 ORFs organized in two divergent operons (sacABCD
Externí odkaz:
https://doaj.org/article/90e1a155fab4451f832583a23ad9acee
Publikováno v:
Microbial Cell Factories, Vol 22, Iss 1, Pp 1-9 (2023)
Abstract Background New antibiotics are urgently needed in clinical treatment of superdrug-resistant bacteria. Nonribosomal peptides (NRPs) are a major source of antibiotics because they exhibit structural diversity, and unique antibacterial mechanis
Externí odkaz:
https://doaj.org/article/51d439dbfcf54b9aa74de366aef64faa
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
mSystems, Vol 8, Iss 2 (2023)
ABSTRACT In the search for novel drug candidates, diverse environmental microbiomes have been surveyed for their secondary metabolite biosynthesis potential, yet little is known about the biosynthetic diversity encoded by divergent microbiomes from d
Externí odkaz:
https://doaj.org/article/d93a18e6e272483c99a8b8d74e9c99ca
Autor:
Ana Ceniceros, Librada Cañedo, Carmen Méndez, Carlos Olano, Carmen Schleissner, Carmen Cuevas, Fernando de la Calle, José A. Salas
Publikováno v:
Metabolites, Vol 13, Iss 10, p 1091 (2023)
Three novel lipopeptides, PM130391 (1), PM130392 (2), and PM140293 (3) were obtained from cultures of Streptomyces tuirus PHM034 isolated from a marine sediment. Structural elucidation of the three compounds showed they belong to the nonribosomal pep
Externí odkaz:
https://doaj.org/article/aaa2ae51a5bb42d7bd2dd8950d9374ef
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 343-352 (2022)
As we stand on the brink of the post-antibiotic era, we are in dire need of novel antimicrobial compounds. Microorganisms produce a wealth of so-called secondary metabolites and have been our most prolific source of antibiotics so far. However, redis
Externí odkaz:
https://doaj.org/article/d06bd9bc536340bd815a05746924be48
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 1218-1226 (2022)
Nonribosomal peptides are a class of secondary metabolites synthesized by multimodular enzymes named nonribosomal peptide synthetases and mainly produced by bacteria and fungi. NMR, LC-MS/MS and other analytical methods allow to determine a peptide s
Externí odkaz:
https://doaj.org/article/792b177b823e48b0bb6649a9d3988b56
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.