Effects of fenofibrate on lipid parameters in obese rhesus monkeys

Autor: Deborah A. Winegar, Peter J. Brown, William O. Wilkison, Michael C. Lewis, Ronda J. Ott, W.Q. Tong, H. Roger Brown, Jurgen M. Lehmann, Steven A. Kliewer, Kelli D. Plunket, James M. Way, Noni L. Bodkin, Barbara C. Hansen

Publikováno v: Journal of Lipid Research, Vol 42, Iss 10, Pp 1543-1551 (2001)

Fenofibrate is a member of the fibrate class of hypolipidemic agents used clinically to treat hypertriglyceridemia and mixed hyperlipidemia. The fibrates were developed primarily on the basis of their cholesterol and triglyceride lowering in rodents.

Externí odkaz: https://doaj.org/article/e18df182ec9643e695a1b3b91bee8a1d

Diabetes Performance Measures: Current Status and Future Directions

Autor: Judith E. Fradkin, Sheldon Greenfield, L. Gregory Pawlson, John E. Sutherland, Patrick J. O'Connor, Noni L. Bodkin, Joseph V. Selby, Michael L. Taylor, Eve A. Kerr, Edward W. Gregg, Russell E. Glasgow, Carol Wysham

Publikováno v: Diabetes Care
O'Connor, PJ; Bodkin, NL; Fradkin, J; Glasgow, RE; Greenfield, S; Gregg, E; et al.(2011). Diabetes performance measures: Current status and future directions. Diabetes Care, 34(7), 1651-1659. doi: 10.2337/dc11-0735. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/83k3819g

Just as treatment guidelines for diabetes care were at the forefront of medical guideline development (1), diabetes has been a prominent focus of performance measurement and quality improvement initiatives for well over a decade. However, the constra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::604a6b7b400482517e863dcbeb645e5e
https://doi.org/10.2337/dc11-0735

Glomerular hypertrophy is associated with hyperinsulinemia and precedes overt diabetes in aging rhesus monkeys

Autor: Paul E. Klotman, Roberto Iotti, Jeffrey B. Kopp, Barbara C. Hansen, Jennie W. Owens, Ana María Cusumano, Noni L. Bodkin

Publikováno v: American Journal of Kidney Diseases. 40:1075-1085

Background: Rhesus monkeys have a high prevalence of obesity and spontaneous type 2 diabetes mellitus after the age of 10 years. These monkeys go through a defined, sequential set of metabolic phases, including fasting hyperinsulinemia, impaired gluc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::189ba726126fc748439ff9da39af8abd
https://doi.org/10.1053/ajkd.2002.36348

Galectin-12, an Adipose-expressed Galectin-like Molecule Possessing Apoptosis-inducing Activity

Autor: Morihiro Matsuda, Barbara C. Hansen, Masahiko Takahashi, Yoshihiro Tochino, Shinji Kihara, Hiroshi Kuriyama, Ken Kishida, Yuji Matsuzawa, Tadashi Nakamura, Yuko Matsukawa, Tohru Funahashi, Kikuko Hotta, Hitoshi Nishizawa, Noni L. Bodkin

Publikováno v: Journal of Biological Chemistry. 276:34089-34097

Galectins constitute a family of proteins that bind to beta-galactoside residues and have diverse physiological functions. Here we report on the identification of a galectin-like molecule, galectin-12, in a human adipose tissue cDNA library. The prot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b0be5b0ff8d1900c95c65a99b01f694
https://doi.org/10.1074/jbc.m105097200

A Thiazolidinedione Improves In Vivo Insulin Action on Skeletal Muscle Glycogen Synthase in Insulin-Resistant Monkeys

Autor: Shinji Yoshioka, Heidi K. Ortmeyer, Hiroyoshi Horikoshi, Barbara C. Hansen, Joseph Haney, Noni L. Bodkin

Publikováno v: International journal of experimental diabetes research

Thiazolidinediones (TZD) have been shown to have anti-diabetic effects including the ability to decrease fasting hyperglycemia and hyperinsulinemia, increase insulin-mediated glucose disposal rate (M) and decrease hepatic glucose production, but the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e3779dccb288881f2da647a8d4e9e59
http://europepmc.org/articles/PMC2477731