Výsledky vyhledávání - "Nonhlanhla Mthembu"

Akademický článek

Role of atrial natriuretic peptide in the dissociation between flow relations with ventricular mass and function in a community with volume-dependent hypertension

Autor: Suraj M. Yusuf, Gavin R. Norton, Vernice R. Peterson, Nonhlanhla Mthembu, Carlos D. Libhaber, Grace Tade, Hamza Bello, Adamu J. Bamaiyi, Keneilwe N. Mmopi, Patrick H. Dessein, Ferande Peters, Pinhas Sareli, Angela J. Woodiwiss

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 10 (2023)

BackgroundWhether differential effects of volume load on left ventricular mass (LVM) and function occur in sustained volume-dependent primary hypertension, and the impact of atrial natriuretic peptide (ANP) on these effects, is unknown.MethodsFrom ao

Externí odkaz: https://doaj.org/article/e53a4cf1f1144bc4be90bbefe3b2786d

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Akademický článek

Proximal aortic stiffness modifies the relationship between heart rate and backward wave and hence central arterial pulse pressure

Autor: Nonhlanhla Mthembu, Vernice R. Peterson, Gavin R. Norton, Eitzaz Sadiq, Andrea Kolkenbeck-Ruh, Ravi Naran, Suraj M. Yusuf, Grace Tade, Hamza Bello, Adamu Bamaiyi, Carlos D. Libhaber, Patrick Dessein, Ferande Peters, Taalib Monareng, Talib Abdool-Carrim, Ismail Cassimjee, Pinhas Sareli, Girish Modi, Angela J. Woodiwiss

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 9 (2022)

AimsA lower heart rate (HR) increases central blood pressure through enhanced backward wave pressures (Pb). We aimed to determine whether these relationships are modified by increases in aortic stiffness.MethodsUsing non-invasive central pressure, ao

Externí odkaz: https://doaj.org/article/e3f3aeee31f94464912d9f093f56c3e0

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Contribution of Increases in Late Systolic Ejection Volume to the Impact of Heart Rate on Central Arterial Pulse Pressure in a Community Sample

Autor: Nonhlanhla Mthembu, Gavin R Norton, Vernice R Peterson, Ravi Naran, Suraj M Yusuf, Grace Tade, Hamza Bello, Adamu Bamaiyi, Carlos D Libhaber, Patrick Dessein, Ferande Peters, Pinhas Sareli, Angela J Woodiwiss

Publikováno v: American Journal of Hypertension. 35:989-997

BACKGROUND A lower heart rate (HR) increases left ventricular (LV) ejection volume. Whether this contributes to the adverse effects of HR on central pulse pressure (PPc) through reservoir volume effects is uncertain. METHODS Using noninvasive central

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::096ae19243e4067d9e07f970a43a625d
https://doi.org/10.1093/ajh/hpac097

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Attenuated Relationships Between Indexes of Volume Overload and Atrial Natriuretic Peptide in Uncontrolled, Sustained Volume-Dependent Primary Hypertension

Autor: Suraj M. Yusuf, Gavin R. Norton, Vernice R. Peterson, Nico Malan, Monica Gomes, Nonhlanhla Mthembu, Carlos D. Libhaber, Grace Tade, Hamza Bello, Adamu J. Bamaiyi, Keneilwe N. Mmopi, Ferande Peters, Pinhas Sareli, Patrick H. Dessein, Angela J. Woodiwiss

Publikováno v: Hypertension (Dallas, Tex. : 1979). 80(1)

Background: Whether systolic blood pressure (SBP) control in sustained volume-dependent primary hypertension is associated with blunted ANP (atrial natriuretic peptide) relationships with indexes of volume load is unknown. Methods: Systemic hemodynam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c7514f5e7762fe6a9494564d97a118
https://pubmed.ncbi.nlm.nih.gov/36330806

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Independent relationships between renal mechanisms and systemic flow, but not resistance to flow in primary hypertension in Africa

Autor: Patrick H Dessein, Gavin R. Norton, Keneilwe N. Mmopi, Vernice R. Peterson, Ferande Peters, Nico Malan, Elena Libhaber, Carlos D. Libhaber, Pinhas Sareli, Angela J. Woodiwiss, Daniel Da Silva Fernandes, Grace Tade, Hamza Bello, Suraj M. Yusuf, Nonhlanhla Mthembu, Mohlabani Masiu

Publikováno v: Journal of Hypertension. 39:2446-2454

AIMS Whether renal mechanisms of hypertension primarily translate into increases in systemic vascular resistance (SVR) in all populations is uncertain. We determined whether renal mechanisms associate with either increases in SVR (and impedance to fl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::355a6dee5de793bd421ef2abfaafd1e9
https://doi.org/10.1097/hjh.0000000000002968

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Distinct Contribution of Systemic Blood Flow to Hypertension in an African Population Across the Adult Lifespan

Autor: Daniel Da Silva Fernandes, Angela J. Woodiwiss, Hamza Bello, Pinhas Sareli, Grace Tade, Nonhlanhla Mthembu, Carlos D. Libhaber, Ferande Peters, Gavin R. Norton, Vernice R. Peterson, Mohlabani Masiu, Keneilwe N. Mmopi

Publikováno v: Hypertension. 76:410-419

Although hypertension in groups of African ancestry is volume-dependent, the relative impact of systemic flow (stroke volume, peak aortic flow [Q]) versus vascular mechanisms (systemic vascular resistance, aortic characteristic impedance [Zc], total

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9922898b3b652dc82f8b356b9a71f212
https://doi.org/10.1161/hypertensionaha.120.14925

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Hemodynamic Determinants of Age Versus Left Ventricular Diastolic Function Relations Across the Full Adult Age Range

Autor: Nonhlanhla Mthembu, Vernice R. Peterson, Hamza Bello, Adamu J. Bamaiyi, Ferande Peters, Angela J. Woodiwiss, Carlos D. Libhaber, Mohlabani Masiu, Keneilwe N. Mmopi, Pinhas Sareli, Gavin R. Norton, Daniel Da Silva Fernandes

Publikováno v: Hypertension. 75:1574-1583

The relative contribution of loading conditions at different ages across the full adult lifespan to decreases in left ventricular (LV) diastolic function is unclear. Using central arterial pressure and aortic velocity and diameter measurements in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c38b0555c0f370dc310090cb706fd61
https://doi.org/10.1161/hypertensionaha.119.14622

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Marked intrafamilial aggregation and heritability of aortic flow in a community with prevalent volume-dependent hypertension in Africa

Autor: Suraj M, Yusuf, Gavin R, Norton, Vernice, Peterson, Carlos D, Libhaber, Keneilwe N, Mmopi, Hamza, Bello, Mohlabani, Masiu, Daniel, Da Silva Fernandes, Grace, Tade, Nonhlanhla, Mthembu, Ferande, Peters, Patrick, Dessein, Pinhas, Sareli, Angela J, Woodiwiss

Publikováno v: Journal of Hypertension.

Although peak aortic flow (Q) is now recognized as a major determinant of hypertension in Africa, current therapy has no proven ability to target this change. The mechanisms of this effect, therefore, require elucidation. We compared the intrafamilia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::756a9607511425d4e0195463e4bbdaf8
https://doi.org/10.1097/hjh.0000000000003057

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Clinical Characteristics and Histopathology of Coronavirus Disease 2019-Related Deaths in African Children

Publikováno v: The Pediatric infectious disease journal. 40(9)

BACKGROUND: Globally, very few childhood deaths have been attributed to coronavirus disease 2019 (COVID-19). We evaluated clinical, microbiologic and postmortem histopathologic findings in childhood deaths in whom severe acute respiratory syndrome co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3deeb9483c044aa632af03b154c1350d
https://pubmed.ncbi.nlm.nih.gov/34397776

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Impact of stroke work on the ability of left ventricular mass to account for pressure effects on function in a community with prevalent systemic flow-dependent hypertension

Autor: Daniel Da Silva Fernandes, Pinhas Sareli, Hamza Bello, Keneilwe N. Mmopi, Mohlabani Masiu, Adamu J. Bamaiyi, Ravi Naran, Angela J. Woodiwiss, Vernice R. Peterson, Carlos D. Libhaber, Gavin R. Norton, Ferande Peters, Nonhlanhla Mthembu

Publikováno v: Journal of hypertension. 39(10)

AIMS To determine whether the confounding influence of stroke work on left ventricular mass (LVM) limits the ability of LVM to detect hypertensive LV dysfunction in systemic flow-dependent hypertension. METHODS In a community with prevalent systemic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fe1c529b426a76d4d0dadb58dcc9d70
https://pubmed.ncbi.nlm.nih.gov/34232159

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