Engineered geranyl diphosphate methyltransferase produces 2-methyl-dimethylallyl diphosphate as a noncanonical C6 unit for terpenoid biosynthesis

Autor: Chen-Yang Xia, Bo-Wen Lu, Ji-Yun Cui, Bai-Yang Wang, Yue-Yang Sun, Fei Gan

Publikováno v: Synthetic and Systems Biotechnology, Vol 8, Iss 1, Pp 107-113 (2023)

Terpenoids constitute the largest class of natural products with complex structures, essential functions, and versatile applications. Creation of new building blocks beyond the conventional five-carbon (C5) units, dimethylallyl diphosphate (DMAPP) an

Externí odkaz: https://doaj.org/article/99511563f3d7461081564f74075ce490

Engineered geranyl diphosphate methyltransferase produces 2-methyl-dimethylallyl diphosphate as a noncanonical C 6 unit for terpenoid biosynthesis.

Autor: Xia CY; Hubei Key Laboratory of Cell Homeostasis, College of Life Science, Wuhan University, Wuhan, China., Lu BW; Hubei Key Laboratory of Cell Homeostasis, College of Life Science, Wuhan University, Wuhan, China., Cui JY; Hubei Key Laboratory of Cell Homeostasis, College of Life Science, Wuhan University, Wuhan, China., Wang BY; Hubei Key Laboratory of Cell Homeostasis, College of Life Science, Wuhan University, Wuhan, China., Sun YY; Hubei Key Laboratory of Cell Homeostasis, College of Life Science, Wuhan University, Wuhan, China., Gan F; Hubei Key Laboratory of Cell Homeostasis, College of Life Science, Wuhan University, Wuhan, China.; TaiKang Center for Life and Medical Science, Wuhan University, Wuhan, China.; Hubei Provincial Cooperative Innovation Center of Industrial Fermentation, Wuhan, China.

Publikováno v: Synthetic and systems biotechnology [Synth Syst Biotechnol] 2022 Dec 19; Vol. 8 (1), pp. 107-113. Date of Electronic Publication: 2022 Dec 19 (Print Publication: 2023).