Engineered geranyl diphosphate methyltransferase produces 2-methyl-dimethylallyl diphosphate as a noncanonical C6 unit for terpenoid biosynthesis.

Autor: Chen-Yang Xia¹, Bo-Wen Lu¹, Ji-Yun Cui¹, Bai-Yang Wang¹, Yue-Yang Sun¹, Fei Gan^1,2,3 feigan@whu.edu.cn

Publikováno v: Synthetic & Systems Biotechnology. Mar2023, Vol. 8 Issue 1, p107-113. 7p.

The Great Codon Escape: Vacating Codons for Genetic Code Expansion and Ribosome Stalling.

Autor: Hopstaken, Antonius J. P., Große Wichtrup, Enno, Jongkees, Seino A. K.

Publikováno v: Israel Journal of Chemistry; Sep2024, Vol. 64 Issue 8/9, p1-13, 13p

Tethered Ribosomes: Toward the Synthesis of Nonproteinogenic Polymers in Bacteria.

Autor: Stan, Andreea, Mayer, Clemens

Publikováno v: ChemBioChem; Jun2023, Vol. 24 Issue 12, p1-11, 11p

Engineered geranyl diphosphate methyltransferase produces 2-methyl-dimethylallyl diphosphate as a noncanonical C 6 unit for terpenoid biosynthesis.

Autor: Xia CY; Hubei Key Laboratory of Cell Homeostasis, College of Life Science, Wuhan University, Wuhan, China., Lu BW; Hubei Key Laboratory of Cell Homeostasis, College of Life Science, Wuhan University, Wuhan, China., Cui JY; Hubei Key Laboratory of Cell Homeostasis, College of Life Science, Wuhan University, Wuhan, China., Wang BY; Hubei Key Laboratory of Cell Homeostasis, College of Life Science, Wuhan University, Wuhan, China., Sun YY; Hubei Key Laboratory of Cell Homeostasis, College of Life Science, Wuhan University, Wuhan, China., Gan F; Hubei Key Laboratory of Cell Homeostasis, College of Life Science, Wuhan University, Wuhan, China.; TaiKang Center for Life and Medical Science, Wuhan University, Wuhan, China.; Hubei Provincial Cooperative Innovation Center of Industrial Fermentation, Wuhan, China.

Publikováno v: Synthetic and systems biotechnology [Synth Syst Biotechnol] 2022 Dec 19; Vol. 8 (1), pp. 107-113. Date of Electronic Publication: 2022 Dec 19 (Print Publication: 2023).

Synthesis of 11-carbon terpenoids in yeast using protein and metabolic engineering

Autor: Codruta, Ignea, Marianna, Pontini, Mohammed S, Motawia, Massimo E, Maffei, Antonios M, Makris, Sotirios C, Kampranis

Publikováno v: Nature chemical biology. 14(12)

One application of synthetic biology is the redesign of existing biological systems to acquire new functions. In this context, expanding the chemical code underlying key biosynthetic pathways will lead to the synthesis of compounds with new structure

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f21e2aba0a552e424ae0cefccb7897b4
https://pubmed.ncbi.nlm.nih.gov/30429603