Zobrazeno 1 - 10
of 502
pro vyhledávání: '"Non-ribosomal peptide synthetase"'
Publikováno v:
Shipin gongye ke-ji, Vol 45, Iss 17, Pp 445-453 (2024)
Secondary metabolites (SM) produced by filamentous fungi have been extensively applied in biomedicine, biological control, food, and other fields. The biosynthesis of most SMs is closely associated with the catalysis of non-ribosome peptide synthetas
Externí odkaz:
https://doaj.org/article/f642fb641ad1497ebd703698ae092dd1
Autor:
Lucía Graña-Miraglia, Jorge Luis Geney Higuita, Juan Carlos Salazar, Diana Guaya Iñiguez, Carlos Alcolado León, Víctor A. García-Angulo
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Pyoverdines are high affinity siderophores produced by most Pseudomonas with a wide role in microbial interspecies interactions. They are primarily composed of a conserved chromophore moiety, an acyl side chain and a peptide backbone which may be hig
Externí odkaz:
https://doaj.org/article/72697815a685425aa29367d4af57591c
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-22 (2024)
Abstract Fungal non-ribosomal peptide synthetase (NRPS)-encoding products play a paramount role in new drug discovery. Fusarium, one of the most common filamentous fungi, is well-known for its biosynthetic potential of NRPS-type compounds with divers
Externí odkaz:
https://doaj.org/article/255cb9baf07d4dd78fc4fb03488826bc
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 321-330 (2024)
Several under-explored Aspergillus sp. produce intriguing heptapeptides containing a γ-aminobutyric acid (GABA) residue with as yet unknown biological functions. In this study, a new GABA-containing heptapeptide – unguisin J (1) – along with kno
Externí odkaz:
https://doaj.org/article/46568e21c00244a1b7a147d43b796093
Publikováno v:
Insects, Vol 15, Iss 9, p 710 (2024)
Entomopathogenic bacteria, classified into the genus Xenorhabdus, exhibit a dual lifestyle as mutualistic symbionts to Steinernema nematodes and as pathogens to a broad range of insects. Bacterial virulence depends on toxin proteins that induce toxem
Externí odkaz:
https://doaj.org/article/97f3bd087c11411b82a6b21f60b75305
Autor:
Songya Zhang, Lin Zhang, Anja Greule, Julien Tailhades, Edward Marschall, Panward Prasongpholchai, Daniel J. Leng, Jingfan Zhang, Jing Zhu, Joe A. Kaczmarski, Ralf B. Schittenhelm, Oliver Einsle, Colin J. Jackson, Fabrizio Alberti, Andreas Bechthold, Youming Zhang, Manuela Tosin, Tong Si, Max J. Cryle
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 8, Pp 3561-3574 (2023)
WS9326A is a peptide antibiotic containing a highly unusual N-methyl-E-2-3-dehydrotyrosine (NMet-Dht) residue that is incorporated during peptide assembly on a non-ribosomal peptide synthetase (NRPS). The cytochrome P450 encoded by sas16 (P450Sas) ha
Externí odkaz:
https://doaj.org/article/7d63ec27ecab4b6da2493ecc0f966b70
Publikováno v:
Frontiers in Natural Products, Vol 3 (2024)
Peptide natural products have a wide range of useful applications as pesticides, veterinary agents, pharmaceuticals, and bioproducts. To discover new natural products, manipulate them for analog generation, and to harness the potential of these bioac
Externí odkaz:
https://doaj.org/article/2389086540cc49908e6a3cca38c6a540
Autor:
Natapol Pumipuntu, Thanyaphorn Chamnandee, Kittisak Saengthong, Suvit Pathomthanasarn, Tawatchai Tanee, Pensri Kyes, Penkhae Thamsenanupap, Apichat Karaket, Marilyn C. Roberts, Randall C. Kyes
Publikováno v:
Veterinary World, Vol 15, Iss 11, Pp 2693-2698 (2022)
Background and Aim: In the past, the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) infections in both humans and animals has increased across Thailand. Staphylococcus argenteus has been associated with infections among humans, exot
Externí odkaz:
https://doaj.org/article/e39aea8acb434b339db1c7e73f515c6d
Publikováno v:
Synthetic and Systems Biotechnology, Vol 7, Iss 2, Pp 677-688 (2022)
Non-ribosomal peptide synthetases (NRPSs) are attractive targets for biosynthetic pathway engineering due to their modular architecture and the therapeutic relevance of their products. With catalysis mediated by specific protein-protein interactions
Externí odkaz:
https://doaj.org/article/388ffd2bdbb74001847a74c21c99f500
Autor:
Wahyu Setia Widodo, Sonja Billerbeck
Publikováno v:
Engineering Microbiology, Vol 3, Iss 1, Pp 100067- (2023)
Cyclodipeptides are diverse chemical scaffolds that show a broad range of bioactivities relevant for medicine, agriculture, chemical catalysis, and material sciences. Cyclodipeptides can be synthesized enzymatically through two unrelated enzyme famil
Externí odkaz:
https://doaj.org/article/3620eda73f394099a9d0eefbf454f10a