Innate immune stimulation of whole blood reveals IFN-1 hyper-responsiveness in type 1 diabetes

Autor: Carla J. Greenbaum, Peter S. Linsley, Matthew J. Dufort, Cate Speake, Vincent Bondet, Darragh Duffy, Kameron B. Rodrigues, M. Jubayer Rahman, Alba Llibre, Kristin V. Tarbell, Juan Quiel

Publikováno v: Diabetologia
Diabetologia, Springer Verlag, 2020, ⟨10.1007/s00125-020-05179-4⟩
Diabetologia, 2020, ⟨10.1007/s00125-020-05179-4⟩

Self-antigen-specific T cell responses drive type 1 diabetes pathogenesis, but alterations in innate immune responses are also critical and not as well understood. Innate immunity in human type 1 diabetes has primarily been assessed via gene-expressi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61dc6fa54e0d4c6ff16b6e17cea62de1
https://pubmed.ncbi.nlm.nih.gov/32500289